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| Molecular Profile | FGFR2 over exp |
| Therapy | Fexagratinib |
| Indication/Tumor Type | endometrial cancer |
| Response Type | resistant |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 over exp | endometrial cancer | resistant | Fexagratinib | Preclinical - Cell culture | Actionable | In a preclinical study, endometrial cells with Fgfr2 overexpression were resistant to the anti-proliferative effects of Fexagratinib (AZD4547) (PMID: 26294741). | 26294741 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (26294741) | Antitumor Effects and Mechanisms of AZD4547 on FGFR2-Deregulated Endometrial Cancer Cells. | Full reference... |