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| Profile Treatment Approach Name | CDK4/6 Inhibitor |
| Profile Name | CDKN2A del |
| Drug Class | CDK4/6 Inhibitor 14 |
| Therapy |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (24495407) | Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines. | Full reference... |
| (23898052) | PD-0332991, a potent and selective inhibitor of cyclin-dependent kinase 4/6, demonstrates inhibition of proliferation in renal cell carcinoma at nanomolar concentrations and molecular markers predict for sensitivity. | Full reference... |