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Profile Treatment Approach Name PD-L1/PD-1 antibody
Profile Name MLH1 negative
Drug Class PD-L1/PD-1 antibody 122
Therapy

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PubMed Id Reference Title Details
(28734759) Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study. Full reference...
(33001143) Clinical Activity and Safety of the Anti-Programmed Death 1 Monoclonal Antibody Dostarlimab for Patients With Recurrent or Advanced Mismatch Repair-Deficient Endometrial Cancer: A Nonrandomized Phase 1 Clinical Trial. Full reference...
(30787022) FDA Approval Summary: Pembrolizumab for the Treatment of Microsatellite Instability-High Solid Tumors. Full reference...
(27412392) Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade. Full reference...