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Profile Treatment Approach Name | FGFR Inhibitor (Pan) |
Profile Name | FGFR2 rearrange |
Drug Class | FGFR Inhibitor (Pan) 26 |
Therapy |
PubMed Id | Reference Title | Details |
---|---|---|
(28416604) | Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib. | Full reference... |
(31088831) | Multicenter Phase I Study of Erdafitinib (JNJ-42756493), Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients with Advanced or Refractory Solid Tumors. | Full reference... |
Final results from a phase II study of infigratinib (BGJ398), an FGFR-selective tyrosine kinase inhibitor, in patients with previously treated advanced cholangiocarcinoma harboring an FGFR2 gene fusion or rearrangement. | Full reference... |