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Profile Treatment Approach Name | mTORC1 Inhibitor |
Profile Name | FBXW7 S282* |
Drug Class | mTORC1 Inhibitor 9 |
Therapy |
PubMed Id | Reference Title | Details |
---|---|---|
(18787170) | FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. | Full reference... |
(24586741) | FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors. | Full reference... |