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Ref Type | Journal Article | ||||||||||||
PMID | (23630205) | ||||||||||||
Authors | Rumi E, Milosevic JD, Casetti I, Dambruoso I, Pietra D, Boveri E, Boni M, Bernasconi P, Passamonti F, Kralovics R, Cazzola M | ||||||||||||
Title | Efficacy of ruxolitinib in chronic eosinophilic leukemia associated with a PCM1-JAK2 fusion gene. | ||||||||||||
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Abstract Text |
Molecular Profile | Treatment Approach |
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JAK2 fusion | JAK2 Inhibitor - ATP competitive |
JAK2 rearrange | JAK2 Inhibitor - ATP competitive |
Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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