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PMID (38429896)
Authors Inoue T, Kunimasa K, Tamiya M, Kawamura T, Minami T, Nishino K
Title Exceptionally long-lasting response to dabrafenib plus trametinib treatment in a patient with lung adenocarcinoma harboring the BRAF V600E mutation with high expression of PD-L1: A case report.
Journal Vol Issue Date Pages Journal Short Title
Thoracic cancer 2024 Mar 01 Thorac Cancer
URL
Abstract Text We present a patient with lung adenocarcinoma showing high PD-L1 expression and BRAF V600E mutation, who achieved a remarkable long-term response to the combination therapy of dabrafenib and trametinib (DT treatment) after disease progression on immunotherapy. This case may provide an opportunity for clinicians to consider the order of administration of immunotherapy and molecular targeted therapy for BRAF V600E-positive lung cancer.

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