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| NCT ID | NCT02017717 |
| Title | A Randomized Study of Nivolumab Versus Bevacizumab and a Safety Study of Nivolumab in Adult Subjects With Recurrent Glioblastoma (GBM) (CheckMate 143) |
| Acronym | CheckMate 143 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Bristol-Myers Squibb |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | POL | NLD | ITA | GBR | FRA | ESP | DNK | DEU | CHE | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Aarhus University Hospital | Aarhus C | 8000 | Denmark | Details | ||
| Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | United States | Details | |
| Azienda Ospedaliera Citta della Salute e della Scienza | Torino | 10126 | Italy | Details | ||
| Beth Israel Deaconess Med Ctr | Boston | Massachusetts | 02215 | United States | Details | |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | United States | Details | |
| Centre hospitalier universitaire Vaudois (CHUV) | Lausanne | BT 02252 | Switzerland | Details | ||
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| Georgetown University | Washington | District of Columbia | 20007 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202-2608 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Johns Hopkins University School Of Medicine | Baltimore | Maryland | 21287 | United States | Details | |
| Klinikum Der J. W. Goethe-Universitaet Frankfurt/Main | Frankfurt Am Main | 60528 | Germany | Details | ||
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | United States | Details | |
| Local Institution | Liverpool | New South Wales | 2170 | Australia | Details | |
| Local Institution | East Bentleigh | Victoria | 3165 | Australia | Details | |
| Local Institution | Heidelberg | Victoria | 3084 | Australia | Details | |
| Local Institution | Nedlands | Western Australia | 6009 | Australia | Details | |
| Local Institution | Brussels | 1090 | Belgium | Details | ||
| Local Institution | Bruxelles | 1200 | Belgium | Details | ||
| Local Institution | Bron cedex | 69677 | France | Details | ||
| Local Institution | Marseille Cedex 5 | 13385 | France | Details | ||
| Local Institution | Paris cedex 13 | 75651 | France | Details | ||
| Local Institution | Paris | 75010 | France | Details | ||
| Local Institution | Heidelberg | 69120 | Germany | Details | ||
| Local Institution | Bologna | 40139 | Italy | Details | ||
| Local Institution | Milano | 20133 | Italy | Details | ||
| Local Institution | Siena | 53100 | Italy | Details | ||
| Local Institution | Amsterdam | 1066CX | Netherlands | Details | ||
| Local Institution | Groningen | 9713 AP | Netherlands | Details | ||
| Local Institution | Gdansk | 80-952 | Poland | Details | ||
| Local Institution | Warszawa | 02-781 | Poland | Details | ||
| Local Institution | Barcelona | 08035 | Spain | Details | ||
| Local Institution | Madrid | 28009 | Spain | Details | ||
| Local Institution | Madrid | 28041 | Spain | Details | ||
| Local Institution | Pamplona | 31008 | Spain | Details | ||
| Local Institution | London | Greater London | NW1 2PG | United Kingdom | Details | |
| Local Institution | Manchester | Greater Manchester | M20 4BX | United Kingdom | Details | |
| Local Institution | Liverpool | L7 8YA | United Kingdom | Details | ||
| Local Institution - 0001 | New Haven | Connecticut | 06520 | United States | Details | |
| Local Institution - 0002 | Atlanta | Georgia | 30322 | United States | Details | |
| Local Institution - 0003 | New York | New York | 10065 | United States | Details | |
| Local Institution - 0005 | Nashville | Tennessee | 37232 | United States | Details | |
| Local Institution - 0006 | Boston | Massachusetts | 02215 | United States | Details | |
| Local Institution - 0007 | Durham | North Carolina | 27710 | United States | Details | |
| Local Institution - 0008 | Baltimore | Maryland | 21287 | United States | Details | |
| Local Institution - 0009 | Los Angeles | California | 90095-1769 | United States | Details | |
| Local Institution - 0010 | Bologna | 40139 | Italy | Details | ||
| Local Institution - 0011 | Milano | 20133 | Italy | Details | ||
| Local Institution - 0012 | Siena | 53100 | Italy | Details | ||
| Local Institution - 0013 | Torino | 10126 | Italy | Details | ||
| Local Institution - 0014 | San Francisco | California | 94143-0372 | United States | Details | |
| Local Institution - 0015 | Manchester | Greater Manchester | M20 4BX | United Kingdom | Details | |
| Local Institution - 0017 | Liverpool | L7 8YA | United Kingdom | Details | ||
| Local Institution - 0018 | London | Greater London | NW1 2PG | United Kingdom | Details | |
| Local Institution - 0020 | Seattle | Washington | 98122 | United States | Details | |
| Local Institution - 0021 | Aurora | Colorado | 80045 | United States | Details | |
| Local Institution - 0023 | Charleston | South Carolina | 29425 | United States | Details | |
| Local Institution - 0024 | Houston | Texas | 77030-4009 | United States | Details | |
| Local Institution - 0032 | Nedlands | Western Australia | 6009 | Australia | Details | |
| Local Institution - 0033 | Heidelberg | Victoria | 3084 | Australia | Details | |
| Local Institution - 0034 | East Bentleigh | Victoria | 3165 | Australia | Details | |
| Local Institution - 0035 | Liverpool | New South Wales | 2170 | Australia | Details | |
| Local Institution - 0036 | Frankfurt Am Main | 60528 | Germany | Details | ||
| Local Institution - 0037 | Bonn | 53127 | Germany | Details | ||
| Local Institution - 0038 | Heidelberg | 69120 | Germany | Details | ||
| Local Institution - 0039 | Lausanne | BT 02252 | Switzerland | Details | ||
| Local Institution - 0040 | Zuerich | 8091 | Switzerland | Details | ||
| Local Institution - 0041 | Muenster | 48149 | Germany | Details | ||
| Local Institution - 0043 | Boston | Massachusetts | 02215 | United States | Details | |
| Local Institution - 0045 | Madrid | 28009 | Spain | Details | ||
| Local Institution - 0046 | Madrid | 28041 | Spain | Details | ||
| Local Institution - 0047 | Barcelona | 08035 | Spain | Details | ||
| Local Institution - 0049 | Cleveland | Ohio | 44106 | United States | Details | |
| Local Institution - 0050 | Brussels | 1090 | Belgium | Details | ||
| Local Institution - 0051 | Bruxelles | 1200 | Belgium | Details | ||
| Local Institution - 0055 | Los Angeles | California | 90048 | United States | Details | |
| Local Institution - 0056 | Boston | Massachusetts | 02215 | United States | Details | |
| Local Institution - 0057 | Odense C | 5000 | Denmark | Details | ||
| Local Institution - 0058 | Aarhus C | 8000 | Denmark | Details | ||
| Local Institution - 0059 | Warszawa | 02-781 | Poland | Details | ||
| Local Institution - 0060 | Gdansk | 80-952 | Poland | Details | ||
| Local Institution - 0062 | Bron cedex | 69677 | France | Details | ||
| Local Institution - 0063 | Marseille Cedex 5 | 13385 | France | Details | ||
| Local Institution - 0064 | Paris cedex 13 | 75651 | France | Details | ||
| Local Institution - 0066 | Groningen | 9713 AP | Netherlands | Details | ||
| Local Institution - 0067 | Amsterdam | 1066CX | Netherlands | Details | ||
| Local Institution - 0068 | Paris | 75010 | France | Details | ||
| Local Institution - 0070 | Pamplona | 31008 | Spain | Details | ||
| Massachusetts General Hospital | Boston | Massachusetts | 02215 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Medical University Of South Carolina | Charleston | South Carolina | 29425 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Odense University Hospital | Odense C | 5000 | Denmark | Details | ||
| Preston Robert Tisch Brain Tumor Center at Duke University | Durham | North Carolina | 27710 | United States | Details | |
| Swedish Neuroscience Institute | Seattle | Washington | 98122 | United States | Details | |
| The Regents of the University of California, San Francisco | San Francisco | California | 94143-0372 | United States | Details | |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| Thomas Jefferson University - Clinical Research Institute | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| UCLA Neuro-Oncology Program | Los Angeles | California | 90095-1769 | United States | Details | |
| Universitaetsklinikum Bonn | Bonn | 53127 | Germany | Details | ||
| Universitaetsklinikum Muenster | Muenster | 48149 | Germany | Details | ||
| UniversitaetsSpital Zurich | Zuerich | 8091 | Switzerland | Details | ||
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | United States | Details | |
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-3410 | United States | Details | |
| University Of Texas Md Anderson Cancer Ctr | Houston | Texas | 77030-4009 | United States | Details | |
| University Of Virginia Health System | Charlottesville | Virginia | 22908 | United States | Details | |
| University of Washington - Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | United States | Details | |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| Yale University School Of Medicine | New Haven | Connecticut | 06520 | United States | Details |
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