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| NCT ID | NCT02075840 |
| Title | A Study Comparing Alectinib With Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer Participants (ALEX) |
| Acronym | ALEX |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | NZL | ITA | ISR | GBR | FRA | ESP | DEU | CHE | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | United States | Details | |
| Mayo Clinic Arizona | Phoenix | Arizona | 85259 | United States | Details | |
| North Valley Hem Onc Med Grp; Thomas&Dorothy Leavey Can Ctr | Northridge | California | 91328 | United States | Details | |
| Chao Family Comprehensive Cancer Center; UC Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| TMPN/ Cancer Care Associates | Redondo Beach | California | 90277 | United States | Details | |
| UCSF Helen Diller Family CCC | San Francisco | California | 94158 | United States | Details | |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | United States | Details | |
| St. Mary's Hospital Regional Cancer Center | Grand Junction | Colorado | 81501 | United States | Details | |
| University of Miami-Deerfield Beach | Deerfield Beach | Florida | 33442 | United States | Details | |
| Cancer Institute of Florida PA | Orlando | Florida | 32804 | United States | Details | |
| Memorial Health Care System | Pembroke Pines | Florida | 33028 | United States | Details | |
| Emory University Hospital | Atlanta | Georgia | 30322 | United States | Details | |
| Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital | Marietta | Georgia | 30060 | United States | Details | |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | United States | Details | |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | United States | Details | |
| Beth Israel Deaconess Med Ctr; Hem/Onc | Boston | Massachusetts | 02215 | United States | Details | |
| Dana Farber Can Ins | Boston | Massachusetts | 02215 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Henry Ford Health System | Detroit | Michigan | 48202 | United States | Details | |
| Washington Uni School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| Comprehensive Cancer Center - Peak | Las Vegas | Nevada | 89128 | United States | Details | |
| Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | United States | Details | |
| UT Southwestern Medical Center | Dallas | Texas | 75390-8813 | United States | Details | |
| University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Kinghorn Cancer Centre; St Vincents Hospital | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Royal North Shore Hospital; Oncology | St. Leonards | New South Wales | 2065 | Australia | Details | |
| Calvary Mater Newcastle; Medical Oncology | Waratah | New South Wales | 2298 | Australia | Details | |
| Queen Elizabeth Hospital; Medical Oncology | Woodville South | South Australia | 5011 | Australia | Details | |
| Monash Health Translational Precinct; Clinical Trials Centre, Level 3 | Victoria | 3168 | Australia | Details | ||
| University Clinical Centre of the Republic of Srpska; Clinic for Pulmonary Diseases | Banja Luka | 78000 | Bosnia and Herzegovina | Details | ||
| University Clinical Center Sarajevo;Clinic for Pulmonary disease | Sarajevo | 71000 | Bosnia and Herzegovina | Details | ||
| University Clinical Center Sarajevo;Institute of oncology | Sarajevo | 71000 | Bosnia and Herzegovina | Details | ||
| Hospital das Clinicas - UFRGS | Porto Alegre | RS | 90035-903 | Brazil | Details | |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | Sao Paulo | SP | 01246-000 | Brazil | Details | |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Sunnybrook Odette Cancer Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Mount Sinai Hospital; Oncology | Toronto | Ontario | M5G 1X5 | Canada | Details | |
| Saskatoon Cancer Centre; Uni of Saskatoon Campus | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details | |
| Centro Internacional de Estudios Clínicos (CIEC) | Recoleta | 8420000 | Chile | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou City | 510663 | China | Details | ||
| Shanghai Pulmonary Hospital | Shanghai | 200433 | China | Details | ||
| Clinica CIMCA | San José | 10103 | Costa Rica | Details | ||
| Kasr Eieny Uni Hospital; Oncology (Nemrock) | Cairo | 11555 | Egypt | Details | ||
| Chu Grenoble - Hopital Albert Michallon; Departement de Cancero-Hematologie | Grenoble | 38043 | France | Details | ||
| CHRU de Lille | Lille | 59037 | France | Details | ||
| Centre Leon Berard; Departement Oncologie Medicale | Lyon | 69373 | France | Details | ||
| Hopital Haut Leveque | Pessac | 33600 | France | Details | ||
| Hopital Pontchaillou | Rennes | 35033 | France | Details | ||
| St. Vincentius Kliniken Karlsruhe; Abteilung Hämatologie / Onkologie | Karlsruhe | 76137 | Germany | Details | ||
| Klinik Löwenstein gGmbH Medizinische Klinik II | Löwenstein | 74245 | Germany | Details | ||
| Grupo Angeles | Guatemala City | 01015 | Guatemala | Details | ||
| Pamela Youde Nethersole Eastern Hospital; Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| Princess Margaret Hospital; Oncology | Hong Kong | Hong Kong | Details | |||
| Queen Mary Hospital; Medicine & Respiratory | Hong Kong | Hong Kong | Details | |||
| Tuen Mun Hospital; Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hosp; Dept. Of Clinical Onc | Shatin | Hong Kong | Details | |||
| Rambam Medical Center; Oncology | Haifa | 3109601 | Israel | Details | ||
| Meir Medical Center; Oncology | Kfar-Saba | 4428164 | Israel | Details | ||
| Seconda Universita' Degli Studi; Divsione Di Oncologia Medica | Napoli | Campania | 80131 | Italy | Details | |
| A.O. Universitaria Di Parma; Oncologia Medica | Parma | Emilia-Romagna | 43100 | Italy | Details | |
| Ospedale Provinciale Santa Maria Delle Croci; Oncologia Medica | Ravenna | Emilia-Romagna | 48100 | Italy | Details | |
| Policlinico Umberto i di Roma; dip. Scienze Radiologiche, Oncologiche, Anatomopatologiche | Roma | Lazio | 00161 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1 | Milano | Lombardia | 20133 | Italy | Details | |
| Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica | Milano | Lombardia | 20141 | Italy | Details | |
| Az. Osp. S. Luigi Gonzaga; Malattie Apparato Respiratorio 5 Ad Indirizzo Oncologico | Orbassano | Piemonte | 10043 | Italy | Details | |
| Irccs Ist. Tumori Giovanni Paolo Ii; Dipartimento Oncologia Medica | Bari | Puglia | 70124 | Italy | Details | |
| Az Ospedaliera Nuovo Garibaldi Quartiere Nesima; Oncologia Medica | Catania | Sicilia | 95122 | Italy | Details | |
| Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia; Oncologia Medica | Sant'Andrea Delle Fratte (PG) | Umbria | 06132 | Italy | Details | |
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 463-707 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Instituto Nacional De Enfermedades Respiratorias;Unidad de Investigación | Ciudad de México | Mexico CITY (federal District) | 14080 | Mexico | Details | |
| Uni of Auckland; Medical School | Auckland | New Zealand | Details | |||
| Uniwersyteckie Centrum Kliniczne; Klinika Onkologii i Radioterapii | Gdansk | 80-214 | Poland | Details | ||
| Ms Clinsearch Specjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej | Lublin | 20-064 | Poland | Details | ||
| Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie; Oddzial onkologii z pododdzialem chemioterapii | Olsztyn | 10-357 | Poland | Details | ||
| Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy; Oddzial Iii | Otwock | 05-400 | Poland | Details | ||
| Centrum Onkologii - Inst.Im. Marii Sklodowskiej-Curie; Oncology | Warszawa | 02-781 | Poland | Details | ||
| CHUC - Unidade de Pneumologia Oncológica; Hospital de Dia de Oncologia Edificio Sao Jeronimo | Coimbra | 3000-075 | Portugal | Details | ||
| IPO de Lisboa; Servico de Pneumologia | Lisboa | 1099-023 | Portugal | Details | ||
| IPO do Porto; Servico de Oncologia Medica | Porto | 4200-072 | Portugal | Details | ||
| Medical Radiological Research Centre Rams; Dept. of Radiotherapy & Chemotherapy of Hemoblastosis | Obninsk | Kaluga | 249036 | Russian Federation | Details | |
| Moscow City Oncology Hospital #62 | Moscovskaya Oblast | Moskovskaja Oblast | 143423 | Russian Federation | Details | |
| N.N.Burdenko Main Military Clinical Hospital; Oncology Dept | Moscow | Moskovskaja Oblast | 105229 | Russian Federation | Details | |
| SPb City Clin Onc Dsp; Chemotherapy | Sankt-peterburg | Sankt Petersburg | 197022 | Russian Federation | Details | |
| Scientific Research Oncology Institute named after N.N. Petrov; Oncology | St. Petersburg | Sankt Petersburg | 197758 | Russian Federation | Details | |
| City Clinical Hospital No. 1 | Novosibirsk | 630047 | Russian Federation | Details | ||
| Clinical Center of Serbia | Belgrade | 11000 | Serbia | Details | ||
| Institute for pulmonary diseases of Vojvodina | Sremska Kamenica | 21204 | Serbia | Details | ||
| National University Hospital; National University Cancer Institute, Singapore (NCIS) | Singapore | 119228 | Singapore | Details | ||
| National Cancer Centre; Medical Oncology | Singapore | 168583 | Singapore | Details | ||
| Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Univ Vall d'Hebron; Servicio de Oncologia | Sant Andreu de La Barca | Barcelona | 08740 | Spain | Details | |
| Hospital Universitario Puerta de Hierro; Servicio de Oncologia | Majadahonda | Madrid | 28222 | Spain | Details | |
| Hospital General Univ. de Alicante; Servicio de Oncologia | Alicante | 3010 | Spain | Details | ||
| Hospital Universitario Quiron Dexeus | Barcelona | 08028 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Universitaetsspital Basel; Onkologie | Basel | 4031 | Switzerland | Details | ||
| Inselspital Bern; Universitätsklinik für Medizinische Onkologie, Klinische Forschungseinheit | Bern | 3010 | Switzerland | Details | ||
| CHUV; Departement d'Oncologie | Lausanne | 1011 | Switzerland | Details | ||
| UniversitätsSpital Zürich; Zentrum für Hämatologie und Onkologie, Klinik für Onkologie | Zürich | 8091 | Switzerland | Details | ||
| National Cheng Kung Univ Hosp | Tainan | 00704 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei City | 112 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Xitun Dist. | 40705 | Taiwan | Details | ||
| National Cancer Inst. | Bangkok | 10400 | Thailand | Details | ||
| Chiang Rai Prachanukroh Hospital; Department Of Medicine | Chiang Rai | 57000 | Thailand | Details | ||
| Khonkaen Hospital | Khonkaen | 40000 | Thailand | Details | ||
| King Chulalongkorn Memorial Hospital; Faculty of Medicine Chulalongkorn University | Patumwan | 10330 | Thailand | Details | ||
| Songklanagarind Hospital; Department of Internal Medicine, Division of Respiratory | Songkhla | 90110 | Thailand | Details | ||
| Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology | Adana | 01230 | Turkey | Details | ||
| Ankara University Medical Faculty; Medikal Onkoloji | Ankara | 06100 | Turkey | Details | ||
| Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department | Edirne | 22770 | Turkey | Details | ||
| Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department | Malatya | 44280 | Turkey | Details | ||
| Dnipropetrovsk State Medical Academy; Chemotherapy Department | Dnipropetrovsk | 49102 | Ukraine | Details | ||
| Karkiv Regional Oncology Center | Kharkiv | 61070 | Ukraine | Details | ||
| Kyiv Regional Oncological Dispensary | Kyiv | 04107 | Ukraine | Details | ||
| Lviv State Oncology Regional Treatment and Diagnostic Centre; Department of hemotherapy | Lviv | 79031 | Ukraine | Details | ||
| Birmingham Heartlands Hospital; Dept of Oncology | Birmingham | B9 5SS | United Kingdom | Details | ||
| University College London Hospital | London | N7 9NH | United Kingdom | Details | ||
| Guys & St Thomas Hospital; Department of Oncology | London | SE1 9RT | United Kingdom | Details |