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| NCT ID | NCT02075840 |
| Title | A Study Comparing Alectinib With Crizotinib in Treatment-Naive Anaplastic Lymphoma Kinase-Positive Advanced Non-Small Cell Lung Cancer Participants (ALEX) |
| Acronym | ALEX |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | NZL | ITA | ISR | GBR | FRA | ESP | CHE | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| North Valley Hem Onc Med Grp | Northridge | California | 91325 | United States | Details | |
| TMPN/ Cancer Care Associates | Redondo Beach | California | 90277 | United States | Details | |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | United States | Details | |
| University of Miami-Deerfield Beach | Deerfield Beach | Florida | 33442 | United States | Details | |
| Massachusetts General Hospital Cancer Center | Boston | Massachusetts | 02114 | United States | Details | |
| Beth Israel Deaconess Med Ctr | Boston | Massachusetts | 02215 | United States | Details | |
| Dana Farber Can Ins | Boston | Massachusetts | 02215 | United States | Details | |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Washington Uni School of Medicine | Saint Louis | Missouri | 63110 | United States | Details | |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | United States | Details | |
| University of Texas M.D. Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Kinghorn Cancer Centre | Darlinghurst | New South Wales | 2010 | Australia | Details | |
| Royal North Shore Hospital | St Leonards | New South Wales | 2065 | Australia | Details | |
| Calvary Mater Newcastle | Waratah | New South Wales | 2298 | Australia | Details | |
| Queen Elizabeth Hospital | Adelaide | South Australia | 5011 | Australia | Details | |
| Monash Health Translational Precinct | Victoria | 3168 | Australia | Details | ||
| University Clinical Center Sarajevo | Sarajevo | 71000 | Bosnia and Herzegovina | Details | ||
| Instituto do Cancer do Estado de Sao Paulo - ICESP | Sao Paulo | São Paulo | 01246-000 | Brazil | Details | |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Sunnybrook Odette Cancer Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| Mount Sinai Hospital | Toronto | Ontario | M5G 1X5 | Canada | Details | |
| Saskatoon Cancer Centre | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details | |
| Centro Internacional de Estudios Clínicos (CIEC) | Santiago | 8420383 | Chile | Details | ||
| Sun Yet-sen University Cancer Center | Guangzhou | 510060 | China | Details | ||
| Shanghai Pulmonary Hospital | Shanghai | 200433 | China | Details | ||
| Clinica CIMCA | San Jose | 10103 | Costa Rica | Details | ||
| Kasr Eieny Uni Hospital | Cairo | 11555 | Egypt | Details | ||
| Chu Grenoble - Hopital Albert Michallon | Grenoble | 38043 | France | Details | ||
| CHRU de Lille | Lille | 59037 | France | Details | ||
| Centre Leon Berard | Lyon | 69373 | France | Details | ||
| Hopital Haut Leveque | Pessac | 33604 | France | Details | ||
| Grupo Angeles | Guatemala City | 01015 | Guatemala | Details | ||
| Tuen Mun Hospital | Hong Kong | 852 | Hong Kong | Details | ||
| Pamela Youde Nethersole Eastern Hospital | Hong Kong | Hong Kong | Details | |||
| Prince of Wales Hosp | Hong Kong | Hong Kong | Details | |||
| Princess Margaret Hospital | Hong Kong | Hong Kong | Details | |||
| Queen Mary Hospital | Hong Kong | Hong Kong | Details | |||
| Rambam Medical Center | Haifa | 4959381 | Israel | Details | ||
| Meir Medical Center | Kfar Saba | 44281 | Israel | Details | ||
| A.O. Universitaria Di Parma | Parma | Emilia-Romagna | 43100 | Italy | Details | |
| Ospedale Provinciale Santa Maria Delle Croci | Ravenna | Emilia-Romagna | 48100 | Italy | Details | |
| Policlinico Umberto i di Roma | Roma | Lazio | 00161 | Italy | Details | |
| Irccs Istituto Nazionale Dei Tumori (Int) | Milano | Lombardia | 20133 | Italy | Details | |
| Irccs Istituto Europeo Di Oncologia (IEO) | Milano | Lombardia | 20141 | Italy | Details | |
| Az. Osp. S. Luigi Gonzaga | Orbassano | Piemonte | 10043 | Italy | Details | |
| Irccs Ist. Tumori Giovanni Paolo Ii | Bari | Puglia | 70124 | Italy | Details | |
| Az Ospedaliera Nuovo Garibaldi Quartiere Nesima | Catania | Sicilia | 95122 | Italy | Details | |
| Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia | Perugia | Umbria | 06156 | Italy | Details | |
| National Cancer Center | Gyeonggi-do | 10408 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Instituto Nacional De Enfermedades Respiratorias | Ciudad de México | Mexico CITY (federal District) | 14080 | Mexico | Details | |
| Uni of Auckland | Auckland | New Zealand | Details | |||
| Uniwersyteckie Centrum Kliniczne | Gda?sk | 80-214 | Poland | Details | ||
| Ms Clinsearch Specjalistyczny Niepubliczny Zaklad Opieki Zdrowotnej | Lublin | 20-064 | Poland | Details | ||
| Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie | Olsztyn | 10-357 | Poland | Details | ||
| Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy | Otwock | 05-400 | Poland | Details | ||
| Centrum Onkologii - Inst.Im. Marii Sklodowskiej-Curie | Warszawa | 02-781 | Poland | Details | ||
| CHUC - Unidade de Pneumologia Oncológica | Coimbra | 3000-075 | Portugal | Details | ||
| IPO de Lisboa | Lisboa | 1099-023 | Portugal | Details | ||
| IPO do Porto | Porto | 4200-072 | Portugal | Details | ||
| Moscow City Oncology Hospital #62 | Moscovskaya Oblast | Moskovskaja Oblast | 143423 | Russian Federation | Details | |
| SPb City Clin Onc Dsp | Sankt-peterburg | Sankt Petersburg | 197022 | Russian Federation | Details | |
| Scientific Research Oncology Institute named after N.N. Petrov | St. Petersburg | Sankt Petersburg | 197758 | Russian Federation | Details | |
| N.N.Burdenko Main Military Clinical Hospital | Moscow | 105229 | Russian Federation | Details | ||
| Clinical Center of Serbia | Belgrade | 11000 | Serbia | Details | ||
| Institute for pulmonary diseases of Vojvodina | Sremska Kamenica | 21204 | Serbia | Details | ||
| National University Hospital | Singapore | 119228 | Singapore | Details | ||
| National Cancer Centre | Singapore | 169610 | Singapore | Details | ||
| Hospital General Univ. de Alicante | Alicante | 3010 | Spain | Details | ||
| Vall d'Hebron Institute of Oncology (VHIO), Barcelona | Barcelona | 08035 | Spain | Details | ||
| Hospital Universitari Germans Trias i Pujol | Barcelona | 08916 | Spain | Details | ||
| Hospital Universitario Puerta de Hierro | Madrid | 28222 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Universitaetsspital Basel | Basel | 4031 | Switzerland | Details | ||
| Inselspital Bern | Bern | 3010 | Switzerland | Details | ||
| CHUV | Lausanne | 1011 | Switzerland | Details | ||
| UniversitätsSpital Zürich | Zürich | 8091 | Switzerland | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| National Cheng Kung Univ Hosp | Tainan | 00704 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 00100 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 00112 | Taiwan | Details | ||
| National Cancer Inst. | Bangkok | 10400 | Thailand | Details | ||
| Chiang Rai Prachanukroh Hospital | Chiang Rai | 57000 | Thailand | Details | ||
| Khonkaen Hospital | Khonkaen | 40000 | Thailand | Details | ||
| King Chulalongkorn Memorial Hospital | Patumwan | 10330 | Thailand | Details | ||
| Songklanagarind Hospital | Songkla | 90110 | Thailand | Details | ||
| Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital | Adana | 01250 | Turkey | Details | ||
| Ankara University Medical Faculty | Ankara | 06100 | Turkey | Details | ||
| Trakya University Medical Faculty Research And Practice Hospital Medical Oncology Department | Edirne | 22770 | Turkey | Details | ||
| Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department | Malatya | 44280 | Turkey | Details | ||
| Kyiv Regional Oncological Dispensary | Kyiv | 04107 | Ukraine | Details | ||
| Lviv State Oncology Regional Treatment and Diagnostic Centre | Lviv | 79031 | Ukraine | Details | ||
| Birmingham Heartlands Hospital | Birmingham | B9 5SS | United Kingdom | Details | ||
| University College London Hospital | London | NW1 - 2PG | United Kingdom | Details | ||
| Guys & St Thomas Hospital | London | SE1 9RT | United Kingdom | Details |