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| NCT ID | NCT02124772 |
| Title | Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | Yes |
| Sponsors | GlaxoSmithKline |
| Indications | |
| Therapies | |
| Age Groups: | child |
| Covered Countries | USA | GBR | FRA | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Novartis Investigative Site | Phoenix | Arizona | 85016-7710 | United States | Details | |
| Novartis Investigative Site | San Francisco | California | United States | Details | ||
| Novartis Investigative Site | Washington | District of Columbia | 20010 | United States | Details | |
| Novartis Investigative Site | Baltimore | Maryland | 21287 | United States | Details | |
| Novartis Investigative Site | Boston | Massachusetts | 02115 | United States | Details | |
| Novartis Investigative Site | Minneapolis | Minnesota | 55455 | United States | Details | |
| Novartis Investigative Site | New York | New York | 10065 | United States | Details | |
| Novartis Investigative Site | Cincinnati | Ohio | 45229 | United States | Details | |
| Novartis Investigative Site | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Novartis Investigative Site | Memphis | Tennessee | 38105-3678 | United States | Details | |
| Novartis Investigative Site | Westmead | New South Wales | 2145 | Australia | Details | |
| Novartis Investigative Site | Toronto | Ontario | M5G 1X8 | Canada | Details | |
| Novartis Investigative Site | Paris Cedex 05 | 75248 | France | Details | ||
| Novartis Investigative Site | Villejuif Cedex | 94805 | France | Details | ||
| Novartis Investigative Site | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Novartis Investigative Site | London | WC1N 3JH | United Kingdom | Details |