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| NCT ID | NCT02702388 |
| Title | Phase 2 Trial of Lenvatinib (E7080) in Subjects With Iodine-131 Refractory Differentiated Thyroid Cancer to Evaluate Whether an Oral Starting Dose of 20 mg or 14 mg Daily Will Provide Comparable Efficacy to a 24 mg Starting Dose, But Have a Better Safety Profile |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Eisai Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult |
| Covered Countries | USA | SWE | ROU | POL | ITA | ISR | GBR | FRA | ESP | DNK | DEU | CAN | BEL | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Facility#1 | La Jolla | California | 92093 | United States | Details | |
| Facility #1 | San Diego | California | 92307 | United States | Details | |
| Facility #1 | Torrance | California | 90502 | United States | Details | |
| Facility #1 | Washington | District of Columbia | 20010 | United States | Details | |
| Facility #1 | Boston | Massachusetts | 02114 | United States | Details | |
| Facility #2 | Boston | Massachusetts | 02115 | United States | Details | |
| Facility #1 | Ann Arbor | Michigan | 48109 | United States | Details | |
| Facility #1 | Detroit | Michigan | 48201 | United States | Details | |
| Facility#2 | Morristown | New Jersey | 07962 | United States | Details | |
| Facility#1 | Summit | New Jersey | 07902 | United States | Details | |
| Facility #1 | Bronx | New York | 10461 | United States | Details | |
| Facility #1 | Columbus | Ohio | 43210 | United States | Details | |
| Facility #1 | Portland | Oregon | 97239 | United States | Details | |
| Facility #2 | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Facility #1 | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Facility #1 | Seattle | Washington | 98109 | United States | Details | |
| Facility #1 | Darlinghurst | New South Wales | Australia | Details | ||
| Facility #1 | Saint Leonards | New South Wales | Australia | Details | ||
| Royal Brisbane and Women's Hospital | Brisbane | Queensland | 4006 | Australia | Details | |
| Facility#2 | Chermside | Queensland | Australia | Details | ||
| Facility #1 | Herston | Queensland | Australia | Details | ||
| Facility #1 | Melbourne | Victoria | Australia | Details | ||
| Facility #1 | Nedlands | Western Australia | Australia | Details | ||
| Facility #1 | Melbourne | Australia | Details | |||
| Facility #1 | Saint Leonards | Australia | Details | |||
| Facility #1 | Edegem | Antwerpen | 2650 | Belgium | Details | |
| Facility #1 | Bruxelles | Brussels | 1200 | Belgium | Details | |
| Facility #2 | Namur | 5000 | Belgium | Details | ||
| Facility #1 | Namur | Belgium | Details | |||
| Facility #1 | Calgary | Alberta | Canada | Details | ||
| Facility #1 | Toronto | Ontario | Canada | Details | ||
| Facility #1 | Quebec | Canada | Details | |||
| Facility #1 | Odense | Syddanmark | DK-5000 | Denmark | Details | |
| Facility #1 | Strasbourg | Bas-Rhin | France | Details | ||
| Facility #1 | Caen | Calvados | 14076 | France | Details | |
| Facility #1 | Dijon | Cote-d'Or | 21079 | France | Details | |
| Facility #1 | Bordeaux | Gironde | France | Details | ||
| Facility #1 | Angers | Maine-et-Loire | France | Details | ||
| Facility #2 | Villejuif | Val-de-Marne | 94805 | France | Details | |
| Facility #1 | Villejuif | Val-de-Marne | France | Details | ||
| Facility #2 | Angers | 49933 | France | Details | ||
| Facility #1 | Bordeaux | 33076 | France | Details | ||
| Facility #1 | Caen | France | Details | |||
| Facility #1 | Dijon | 21079 | France | Details | ||
| Facility #2 | Lyon | 69373 | France | Details | ||
| Facility #1 | Paris | 75013 | France | Details | ||
| Facility #1 | Tubingen | Baden-Wurttemberg | 72076 | Germany | Details | |
| Facility #1 | Wurzburg | Bayern | 97080 | Germany | Details | |
| Facility #1 | Hannover | Niedersachsen | 30625 | Germany | Details | |
| Facility #1 | Essen | Nordrhein-Westfalen | Germany | Details | ||
| Facility #2 | Essen | Nordrhein-Westfalen | Germany | Details | ||
| Facility #1 | Essen | 45147 | Germany | Details | ||
| Facility #1 | Leipzig | Germany | Details | |||
| Facility #1 | Petach Tikva | Israel | Details | |||
| Facility #6 | Roma | Lazio | 144 | Italy | Details | |
| Facility #1 | Roma | Lazio | Italy | Details | ||
| Facility #2 | Roma | Lazio | Italy | Details | ||
| Facility #3 | Roma | Lazio | Italy | Details | ||
| Facility #2 | Milano | Lombardia | Italy | Details | ||
| Facility #3 | Milano | Lombardia | Italy | Details | ||
| Facility #4 | Milano | Lombardia | Italy | Details | ||
| Facility #5 | Milano | Lombardia | Italy | Details | ||
| Facility #1 | Livorno | Toscana | 57100 | Italy | Details | |
| Facility #1 | Pisa | Toscana | Italy | Details | ||
| Facility #6 | Milano | 20122 | Italy | Details | ||
| Facility #7 | Milano | 20149 | Italy | Details | ||
| Facility #2 | Pisa | 56124 | Italy | Details | ||
| Facility #4 | Roma | Italy | Details | |||
| Facility #2 | Rozzano | Italy | Details | |||
| Facility #1 | Torino | Italy | Details | |||
| Facility #1 | Viagrande | Italy | Details | |||
| Facility#1 | Busan | 49241 | Korea, Republic of | Details | ||
| Facility #1 | Goyang-si | Korea, Republic of | Details | |||
| Facility #3 | Seoul | 135-710 | Korea, Republic of | Details | ||
| Facility #4 | Seoul | 137-701 | Korea, Republic of | Details | ||
| Facility #1 | Seoul | Korea, Republic of | Details | |||
| Facility #2 | Seoul | Korea, Republic of | Details | |||
| Facility #2 | Kielce | Poland | Details | |||
| Facility #1 | Cluj-Napoca | Cluj | 400058 | Romania | Details | |
| Facility #1 | Bucharest | 11863 | Romania | Details | ||
| Facility #4 | Saint Petersburg | Leningradskaya O | 197758 | Russian Federation | Details | |
| Facility #3 | Moscow | 115478 | Russian Federation | Details | ||
| Facility #4 | Moscow | 117036 | Russian Federation | Details | ||
| Facility #1 | Moscow | Russian Federation | Details | |||
| Facility #2 | Moscow | Russian Federation | Details | |||
| Facility #1 | Obninsk | 249036 | Russian Federation | Details | ||
| Facility #3 | Saint Petersburg | 197758 | Russian Federation | Details | ||
| Facility #1 | Saint Petersburg | Russian Federation | Details | |||
| Facility #2 | Saint Petersburg | Russian Federation | Details | |||
| Facility #1 | Barcelona | Cataluna | Spain | Details | ||
| Facility #2 | Madrid | Madrid, Communidad Delaware | Spain | Details | ||
| Facility #1 | Badalona | 8035 | Spain | Details | ||
| Facility #2 | Barcelona | 8036 | Spain | Details | ||
| Facility #1 | Madrid | 28034 | Spain | Details | ||
| Facility #2 | Madrid | Spain | Details | |||
| Facility #3 | Madrid | Spain | Details | |||
| Facility #1 | Malaga | 29010 | Spain | Details | ||
| Facility #1 | Goteborg | SE-41345 | Sweden | Details | ||
| Facility #1 | Lund | SE-22185 | Sweden | Details | ||
| Facility #1 | London | City Of London | United Kingdom | Details | ||
| Facility #1 | Glasgow | Glasgow City | United Kingdom | Details |