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| NCT ID | NCT03052608 |
| Title | A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Pfizer |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | NLD | ITA | GBR | FRA | ESP | DEU | CZE | CAN | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Florida Cancer Specialists | Altamonte Springs | Florida | 32701 | United States | Details | |
| Florida Cancer Specialists | Brandon | Florida | 33511 | United States | Details | |
| Florida Cancer Specialists | Clearwater | Florida | 33761 | United States | Details | |
| Florida Cancer Specialists | Gainesville | Florida | 32605 | United States | Details | |
| Florida Cancer Specialists | Largo | Florida | 33770 | United States | Details | |
| Florida Cancer Specialists | Lecanto | Florida | 34461 | United States | Details | |
| Florida Cancer Specialists | Orange City | Florida | 32763 | United States | Details | |
| Florida Cancer Specialists | Orlando | Florida | 32806 | United States | Details | |
| Florida Cancer Specialists | Saint Petersburg | Florida | 33705 | United States | Details | |
| Florida Cancer Specialists | Spring Hill | Florida | 34608 | United States | Details | |
| Florida Cancer Specialists | Tampa | Florida | 33607 | United States | Details | |
| Florida Cancer Specialists | Tavares | Florida | 32778 | United States | Details | |
| Florida Cancer Specialists | The Villages | Florida | 32159 | United States | Details | |
| Florida Cancer Specialists | Winter Park | Florida | 32792 | United States | Details | |
| Massachusetts Eye and Ear Infirmary | Boston | Massachusetts | 02114 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Ophthalmic Consultants of Boston Inc | Boston | Massachusetts | 02114 | United States | Details | |
| The William P. Beetham Eye Institute, Joslin Diabetes Center | Boston | Massachusetts | 02215 | United States | Details | |
| University of Rochester Cancer Center Pharmacy | Rochester | New York | 14642 | United States | Details | |
| University of Rochester Medical Center | Rochester | New York | 14642 | United States | Details | |
| Tennessee Oncology, PLLC | Dickson | Tennessee | 37055 | United States | Details | |
| Tennessee Oncology, PLLC | Franklin | Tennessee | 37067 | United States | Details | |
| Tennessee Oncology, PLLC | Gallatin | Tennessee | 37066 | United States | Details | |
| Tennessee Oncology, PLLC | Hermitage | Tennessee | 37076 | United States | Details | |
| Tennessee Oncology, PLLC | Lebanon | Tennessee | 37090 | United States | Details | |
| Tennessee Oncology, PLLC | Murfreesboro | Tennessee | 37129 | United States | Details | |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | United States | Details | |
| The Sarah Cannon Research Institute. | Nashville | Tennessee | 37203 | United States | Details | |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37205 | United States | Details | |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37207 | United States | Details | |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37211 | United States | Details | |
| Tennessee Oncology, PLLC | Shelbyville | Tennessee | 37160 | United States | Details | |
| Tennessee Oncology, PLLC | Smyrna | Tennessee | 37167 | United States | Details | |
| University of Washington Medical Center | Seattle | Washington | 98195 | United States | Details | |
| Centro de Investigacion Pergamino SA | Pergamino | Buenos Aires | B2700CPM | Argentina | Details | |
| Centro Medico Austral | Caba | C1019ABS | Argentina | Details | ||
| Bendigo Day Surgery Collection Centre and Laboratory | Bendigo | Victoria | 3550 | Australia | Details | |
| Bendigo Medical Imaging, Bendigo Hospital | Bendigo | Victoria | 3550 | Australia | Details | |
| Melbourne Pathology | Bendigo | Victoria | 3550 | Australia | Details | |
| Peter MacCallum Cancer Centre | Melbourne | Victoria | 3000 | Australia | Details | |
| Grand Hopital de Charleroi - Site Notre Dame | Charleroi | 6000 | Belgium | Details | ||
| Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| McGill University Health Centre | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| The Affiliated Hospital of Military Medical Sciences | Beijing | Beijing | 100071 | China | Details | |
| Jilin Provincial Cancer Hospital | Changchun | Jilin | 130012 | China | Details | |
| Shanghai Chest Hospital | Shanghai | Shanghai | 200030 | China | Details | |
| Department of Respiratory,the First Affiliated Hospital of College of Medicine, Zhejiang University | Hangzhou | Zhejiang | 310003 | China | Details | |
| The Second Affiliated Hospital of Zhejiang University School of Medicine | Hangzhou | Zhejiang | 310009 | China | Details | |
| Zhejiang Cancer Hospital | Hangzhou | Zhejiang | 310022 | China | Details | |
| Beijing Cancer Hospital | Beijing | 100142 | China | Details | ||
| Guangdong General Hospital | Guangzhou | 510000 | China | Details | ||
| Fakultni nemocnice Olomouc, Klinika plicnich nemoci a tuberkulozy | Olomouc | 779 00 | Czechia | Details | ||
| Vseobecna fakultni nemocnice v Praze | Praha 2 | 128 08 | Czechia | Details | ||
| Hopital Haut-Léveque-Centre François Magendie | Pessac | Aquitaine | 33604 | France | Details | |
| Hopital de Chevilly Larue | Chevilly Larue | 94550 | France | Details | ||
| Centre Hospitalier du Mans | Le Mans | 72000 | France | Details | ||
| Institut Paoli-Calmettes | Marseille cedex 09 | 13273 | France | Details | ||
| Département d'Imagerie Médicale | Marseille cedex 20 | 13915 | France | Details | ||
| Hôpital Nord | Marseille cedex 20 | 13915 | France | Details | ||
| Service Ophtalmologie | Marseille cedex 20 | 13915 | France | Details | ||
| Groupe Hospitalier Bichat Claude Bernard, AP-HP | Paris | 75018 | France | Details | ||
| CHU de Rennes Hopital Pontchaillou | Rennes cedex 9 | 35033 | France | Details | ||
| CHU de Rennes, Hopital Pontchaillou | Rennes cedex 9 | 35033 | France | Details | ||
| Hopital Foch | Suresnes | 92150 | France | Details | ||
| Hopital Larrey | Toulouse Cedex 9 | 31059 | France | Details | ||
| Hopital Pierre Paul Riquet | Toulouse cedex 9 | 31059 | France | Details | ||
| Hôpital Larrey | Toulouse Cedex 9 | 31059 | France | Details | ||
| Department d'imagerie medicale | Villejuif | 94805 | France | Details | ||
| Institut Gustave Roussy | Villejuif | 94805 | France | Details | ||
| Uberortliche Radiologische Gemeinschaftspraxis Dr. med. Marc Amler | Dresden | 01309 | Germany | Details | ||
| Technische Universitat Dresden , Medizinische Fakultat Carl Gustav Carus | Dresden | D-01307 | Germany | Details | ||
| Thoraxklinik Heidelberg gGmbH | Heidelberg | D-69126 | Germany | Details | ||
| Universitatsklinikum Heidelberg | Heidelberg | D-69126 | Germany | Details | ||
| Universitätsklinikum des Saarlandes, Innere Medizin V | Homburg - Saar | 66421 | Germany | Details | ||
| Universitätsklinikum des Saarlandes | Homburg - Saar | 66421 | Germany | Details | ||
| Universitatsklinikum Regensburg, Institut fur Rontgendiagnostik | Regensburg | 93053 | Germany | Details | ||
| Universitatsklinikum Regensburg, Klinik und Poliklinik fur Innere Medizin II | Regensburg | 93053 | Germany | Details | ||
| The University of Hong Kong, Department of Clinical Oncology | Hong Kong | Hong Kong | Details | |||
| The University of Hong Kong, Department of Medicine | Hong Kong | Hong Kong | Details | |||
| Tuen Mun Hospital | Hong Kong | Hong Kong | Details | |||
| Artemis Hospital | Gurugram | Haryana | 122001 | India | Details | |
| Manipal Hospital | Bangalore | Karnataka | 560017 | India | Details | |
| Srinivasam Cancer Care Multispeciality Hospitals India Pvt Ltd | Bangalore | Karnataka | 560072 | India | Details | |
| Sahyadri Clinical Research and Development Centre | Pune | Maharashtra | 411004 | India | Details | |
| Sahyadri Specialty Hospital | Pune | Maharashtra | 411004 | India | Details | |
| AOU Policlinico Vittorio Emanuele-P.O.G. Rodolico | Catania | CT | 95123 | Italy | Details | |
| ASST Monza - A.O. San Gerardo | Monza | MB | 20900 | Italy | Details | |
| IRCCS Ospedale San Raffaele | Milano | MI | 20132 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | MI | 20133 | Italy | Details | |
| Istituto Europeo di Oncologia | Milano | MI | 20141 | Italy | Details | |
| Istituto Clinico Humanitas | Rozzano | MI | 20089 | Italy | Details | |
| Azienda Ospedaliera di Perugia - Ospedale S. M. Misericordia | Perugia | PG | 06132 | Italy | Details | |
| Centro di Riferimento Oncologico-IRCCS | Pordenone | PN | 33081 | Italy | Details | |
| Azienda Ospedaliero-Universitaria di Parma | Parma | PR | 43126 | Italy | Details | |
| Istituto Nazionale Tumori Regina Elena | Roma | RM | 00144 | Italy | Details | |
| Az.Osp.San Camillo-Forlanini | Roma | RM | 00152 | Italy | Details | |
| Azienda Ospedaliera Dei Colli Ospedale Monaldi | Napoli | 80131 | Italy | Details | ||
| Istituto Nazionale Tumori di Napoli | Napoli | 80131 | Italy | Details | ||
| Ausl della Romagna- Ravenna | Ravenna | 48121 | Italy | Details | ||
| Aichi cancer center central hospital | Nagoya | Aichi | 464-8681 | Japan | Details | |
| Nagoya University Hospital | Nagoya | Aichi | 466-8560 | Japan | Details | |
| National Hospital Organization Shikoku Cancer Center | Matsuyama | Ehime | 791-0280 | Japan | Details | |
| Kurume University Hospital | Kurume | Fukuoka | 830-0011 | Japan | Details | |
| National Hospital Organization Hokkaido Cancer Center | Sapporo | Hokkaido | 003-0804 | Japan | Details | |
| Kanazawa University Hospital | Kanazawa | Ishikawa | 920-8641 | Japan | Details | |
| Kanagawa Cancer Center | Yokohama | Kanagawa | 241-8515 | Japan | Details | |
| Sendai Kousei Hospital | Sendai | Miyagi | 980-0873 | Japan | Details | |
| Sendai Kousei Hospital | Sendai | Miyagi | 981-0914 | Japan | Details | |
| Osaka International Cancer Institute | Osaka-shi | Osaka | 541-8567 | Japan | Details | |
| Kindai University Hospital | Osakasayama | Osaka | 589-8511 | Japan | Details | |
| Shizuoka Cancer Center | Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| National Cancer Center Hospital | Chuo-Ku | Tokyo | 104-0045 | Japan | Details | |
| National Hospital Organization, Yamaguchi-Ube Medical Center | Ube | Yamaguchi | 755-0241 | Japan | Details | |
| The Cancer Institute Hospital of JFCR | Koto-ku, Tokyo | 135-8550 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| Osaka City General Hospital | Osaka | 534-0021 | Japan | Details | ||
| Tokushima University Hospital | Tokushima | 770-8503 | Japan | Details | ||
| Wakayama Medical University Department of Pulmonary Medicine and Oncology | Wakayama | 641-8509 | Japan | Details | ||
| The Catholic University of Korea, St. Vincents Hospital | Suwon | Gyeonggi-do | 16247 | Korea, Republic of | Details | |
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Division of Medical Oncology, Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Ulsan University Hospital | Ulsan | 44033 | Korea, Republic of | Details | ||
| Médicos Especialistas en Cancer S.C. / San Peregrino. | Aguascalientes | 20230 | Mexico | Details | ||
| Instituto Nacional de Cancerologia | Distrito Federal | 14080 | Mexico | Details | ||
| Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas | Distrito Federal | 14080 | Mexico | Details | ||
| University Medical Center Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Klinika Onkologii i Radioterapii Uniwersyteckie Centrum Kliniczne | Gdansk | 80-214 | Poland | Details | ||
| Med-Polonia Sp. z o.o. | Poznan | 60-693 | Poland | Details | ||
| Centrum Medyczne Dom Lekarski S.A. | Szczecin | 70-784 | Poland | Details | ||
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie-Panstwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
| RBHI Kursk Regional Clinical Oncology Dispensary | Kislino, Ryshkovsky Rural Council | Kursk Region | 305 524 | Russian Federation | Details | |
| Budgetary Healthcare Institution Omsk Region "Clinical Oncological Dispensary" | Omsk | OMSK Region | 644013 | Russian Federation | Details | |
| LEC at SBIH "Saint-Petersburg Clinical Research Practical Center of specialized types of | Pesochniy Poselok | Saint-petersburg | 197758 | Russian Federation | Details | |
| Private Medical Institution "Euromedservice" | Pushkin | Saint-petersburg | 196603 | Russian Federation | Details | |
| RBHI Kursk Regional Clinical Oncology Dispensary | Kursk | 305 035 | Russian Federation | Details | ||
| FSBI "N.N.Blokhin Medical Research Center of Oncology" | Moscow | 115478 | Russian Federation | Details | ||
| National University Hospital | Singapore | 119074 | Singapore | Details | ||
| Raffles Hospital | Singapore | 188770 | Singapore | Details | ||
| Institut Catala d'Oncologia L'Hospitalet | L'Hospitalet de Llobregat | Barcelona | 08908 | Spain | Details | |
| Hospital Universitario Insular de Gran Canaria | Las Palmas de Gran Canaria | Canarias | 35016 | Spain | Details | |
| Hospital Universitario Puerta de Hierro Majadahonda | Majadahonda | Madrid | 28222 | Spain | Details | |
| Complejo Hospitalario De Navarra | Pamplona | Navarra | 31008 | Spain | Details | |
| Hospital Teresa Herrera C.H.U.A.C. | A Coruna | 15006 | Spain | Details | ||
| Hospital De La Santa Creu I Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Hospital Universitari Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic i Provincial de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital De La Santa Creu I Sant Pau | Barcelona | 08041 | Spain | Details | ||
| Institut Catala d'Oncologia Girona | Girona | 17007 | Spain | Details | ||
| Hospital Universitario Ramon y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Clinico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario Fundacion Jimenez Diaz | Madrid | 28040 | Spain | Details | ||
| Hospital Universitario La Fe | Valencia | 46026 | Spain | Details | ||
| National Taiwan University Hospital | Taipei | Taiwan ROC | 10002 | Taiwan | Details | |
| Chang Gung Memorial Hospital - Kaohsiung Branch | Kaohsiung | 83301 | Taiwan | Details | ||
| Chung Shan Medical University Hospital | Taichung | 402 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 40705 | Taiwan | Details | ||
| Taipei Veterans General Hospital | Taipei | 112 | Taiwan | Details | ||
| Cukurova University Medical Faculty | Adana | 01330 | Turkey | Details | ||
| Istanbul University Oncology Institute | Istanbul | 34093 | Turkey | Details | ||
| Marmara Univ Pendik Training and Research Hospital | Istanbul | 34899 | Turkey | Details | ||
| Ege University Medical Faculty | Izmir | 35100 | Turkey | Details | ||
| The Ipswich Hospital NHS Trust | Ipswich | Suffolk | IP4 5PD | United Kingdom | Details | |
| Heart of England NHS Foundation Trust, Birmingham Heartlands Hospital | Birmingham | WEST Midlands | B9 5SS | United Kingdom | Details | |
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details |