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| NCT ID | NCT03110562 |
| Title | Bortezomib, Selinexor, and Dexamethasone in Patients With Multiple Myeloma (BOSTON) |
| Acronym | BOSTON |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Karyopharm Therapeutics Inc |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ROU | POL | ITA | ISR | HUN | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BGR | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Boca Raton Clinical Research (BRCR) Medical Center | Plantation | Florida | 33324 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| Kaiser Permanente Hawaii | Honolulu | Hawaii | 96817 | United States | Details | |
| McFarland Clinic | Ames | Iowa | 50010 | United States | Details | |
| Stormont Vail Health Care (Cotton O'Neil Cancer Center ) | Topeka | Kansas | 66606 | United States | Details | |
| Commonwealth Hematology | Danville | Kentucky | 40422 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
| Central Care Cancer Center | Bolivar | Missouri | 65613 | United States | Details | |
| The Valley Hospital Luckow Pavilion | Paramus | New Jersey | 07652 | United States | Details | |
| Mount Sinai | New York | New York | 10029 | United States | Details | |
| The Cancer Institute at St. Francis Hospital | Roslyn | New York | 11576 | United States | Details | |
| Novant-Forsyth Memorial Hospital | Winston-Salem | North Carolina | 27103 | United States | Details | |
| University of Cincinnati Health | Cincinnati | Ohio | 45267 | United States | Details | |
| Southwest Cancer Center of Oklahoma | Lawton | Oklahoma | 73505 | United States | Details | |
| Kaiser Permanente Northwest OR | Portland | Oregon | 97210 | United States | Details | |
| SCOR AnMed Health Cancer Center | Anderson | South Carolina | 29621 | United States | Details | |
| Prairie Lakes Healthcare | Watertown | South Dakota | 57201 | United States | Details | |
| Baylor Sammons Cancer Center | Dallas | Texas | 75246 | United States | Details | |
| University of Texas Southwestern | Dallas | Texas | 75390 | United States | Details | |
| Calvary Mater Newcastle | Waratah | New South Wales | 2298 | Australia | Details | |
| Royal Brisbane and Women's Hospital | Herston | Queensland | 4029 | Australia | Details | |
| Mater Misericordiae Limited and Mater Medical Research | South Brisbane | Queensland | 4101 | Australia | Details | |
| Gold Coast University Hospital | Southport | Queensland | 4215 | Australia | Details | |
| Royal Adelaide Hospital | Adelaide | South Australia | 5000 | Australia | Details | |
| Flinders Medical Centre | Bedford Park | South Australia | 5042 | Australia | Details | |
| St. Vincent's Hospital Melbourne | Fitzroy | Victoria | 3065 | Australia | Details | |
| The Alfred Hospital | Melbourne | Victoria | 3004 | Australia | Details | |
| Medical University Innsbruck, Department of Internal Medicine V (Hematology and Oncology) | Innsbruck | Austria | Details | |||
| University Hospital Krems, Department of Internal Medicine II | Krems | Austria | Details | |||
| Medical University of Vienna | Vienna | 1090 | Austria | Details | ||
| General Hospital Hietzing | Vienna | 1130 | Austria | Details | ||
| Wilhelminen Hospital, Department of Internal Medicine I, Center for Oncology & Hematology | Vienna | 1160 | Austria | Details | ||
| Jules Bordet Institute | Brussels | 1000 | Belgium | Details | ||
| UCL Saint-Luc | Brussels | Belgium | Details | |||
| University Hospital Ghent | Ghent | 9000 | Belgium | Details | ||
| General Hospital Delta | Roeselare | 8800 | Belgium | Details | ||
| St. Augustinus Hospital | Wilrijk | 2610 | Belgium | Details | ||
| University Multiprofile Hospital for Active Treatment, Sveti Georgi Clinic of Clinical Hematology | Plovdiv | 4002 | Bulgaria | Details | ||
| University Multiprofile Hospital for Active Treatment, Sveti Ivan Rilski Clinic of Hematology | Sofia | 1431 | Bulgaria | Details | ||
| Specialized Hospital for Active Treatment of Hematological Diseases, Clinic of Hematology, Dept. of Clinical Hematology | Sofia | 1756 | Bulgaria | Details | ||
| Tom Baker Cancer Center/ Alberta Health Services | Calgary | Alberta | T2N 4Z6 | Canada | Details | |
| Cross Cancer Institute / University of Alberta | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Vancouver General Hospital | Vancouver | British Columbia | V5Z 1M9 | Canada | Details | |
| Queen Elizabeth II Health Sciences Center | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details | |
| North East Cancer Centre Sudbury | Sudbury | Ontario | P3E 5J1 | Canada | Details | |
| Princess Margaret Cancer Research | Toronto | Ontario | M5G 1X5 | Canada | Details | |
| Maisonneuve-Rosemont Hospital | Montreal | Quebec | H1T 2M4 | Canada | Details | |
| Royal Victoria Hospital / McGill University | Montreal | Quebec | H3A 1A1 | Canada | Details | |
| L'Hôtel-Dieu de Québec | Quebec City | Quebec | G1R 2J6 | Canada | Details | |
| Saskatchewan Cancer Agency-Allan Blair Cancer Centre | Regina | Saskatchewan | S4T 7TI | Canada | Details | |
| Saskatoon Cancer Center | Saskatoon | Saskatchewan | S7N 4H4 | Canada | Details | |
| General University Hospital in Prague | Praha 2 | Prague | 128 08 | Czechia | Details | |
| University Hopsital Brno | Brno | 625 00 | Czechia | Details | ||
| University Hospital Hradec Kralove | Hradec Kralove | 500 05 | Czechia | Details | ||
| University Hospital Olomouc | Olomouc | 775 20 | Czechia | Details | ||
| University Hospital Ostrava, Dept. of Hematooncology | Ostrava | 708 52 | Czechia | Details | ||
| University Hospital Kralovske Vinohrady, Clinic of Internal Hematology | Prague | 100 34 | Czechia | Details | ||
| Necker Children's Hospital, Department of Adult Hematology | Paris | Ile De France | 75015 | France | Details | |
| Hospital Center Departmental La Roche-Sur-Yon | La Roche-sur-Yon | 85925 | France | Details | ||
| Claude Huriez Hospital | Lille | 59037 | France | Details | ||
| South Lyon Hospital Center | Lyon | 69002 | France | Details | ||
| Brabois Adults Hospital, University Hospital Center of Nancy | Nancy | 54511 | France | Details | ||
| Nantes University Hospital Center | Nantes | 44093 | France | Details | ||
| Saint-Louis Hospital | Paris | 75475 | France | Details | ||
| Miletrie Hospital, University Hospital Center of Poitiers | Poitiers | 86021 | France | Details | ||
| University Hospital Freiburg, Department of Internal Medicine I | Freiburg | Baden-Wuerttemberg | D-79106 | Germany | Details | |
| Klinikum Leverkusen gGmbH Medizinisxhe Klinik 3 | Leverkusen | North Rhine Westfalia | 51375 | Germany | Details | |
| Group Practice for Hematology and Oncology | Dresden | Saxony | 1307 | Germany | Details | |
| Alexandra General Hospital, Therapeutic Clinic | Athens | 11528 | Greece | Details | ||
| General Hospital of Athens "Evangelismos", Department of Hematology and Lymphoma | Athens | Greece | Details | |||
| University General Hospital of Patra | Pátra | Greece | Details | |||
| Theageneion Cancer Hospital, Hematology Department | Thessaloníki | 54639 | Greece | Details | ||
| Semmelweis University, 1st Department of Internal Medicine | Budapest | H-1083 | Hungary | Details | ||
| Integrated Szent Istvan and Szent laszlo Hospital, Department of Hematology and Stem Cell Transplantation | Budapest | H-1097 | Hungary | Details | ||
| Semmelweis University, 3rd Department of Internal Medicine | Budapest | H-1125 | Hungary | Details | ||
| Kaposi Mor Teaching Hospital, 2nd Department of Internal Medicine | Kaposvar | 7400 | Hungary | Details | ||
| Medical Center of the University of Pecs, Department of Hematology | Pecs | 7624 | Hungary | Details | ||
| Regional Cancer Centre | Patna | Bihar | 800014 | India | Details | |
| Regional Cancer Centre | Thiruvananthapuram | Kerala | 695011 | India | Details | |
| Prince Aly Khan Hospital | Mumbai | Maharashta | 400010 | India | Details | |
| Jaslok Hospital and Research Centre | Mumbai | Maharashta | 400026 | India | Details | |
| Bhaktivedanta Hospital | Thane | Maharashtra | 401107 | India | Details | |
| IMS & SUM Hospital | Bhubaneswar | Odisha | 751003 | India | Details | |
| Postgraduate Institute of Medical Education & Research (PGIMER) | Chandigarh | Punjab | 160012 | India | Details | |
| Dayanand Medical College & Hospital | Ludhiana | Punjab | 141001 | India | Details | |
| Cancer Institute | Chennai | Tamil Nadu | 600020 | India | Details | |
| SRM Institute of Medical Sciences | Chennai | Tamil Nadu | 600026 | India | Details | |
| Saveetha Medical College Hospital | Chennai | Tamil Nadu | 602105 | India | Details | |
| G. Kuppuswamy Naidu Hospital | Coimbatore | Tamil Nadu | 641037 | India | Details | |
| Asviratham Speciality Hospital | Madurai | Tamil Nadu | 625020 | India | Details | |
| Meenakshi Mission Hospital | Madurai | Tamil Nadu | 625107 | India | Details | |
| Yashoda Hospital | Hyderabad | Telengana | 500082 | India | Details | |
| King George's Medical University | Lucknow | Uttar Pradesh | 226003 | India | Details | |
| Netaji Subhash Chandra Bose Cancer Research Institute | Kolkata | West Bengal | 700094 | India | Details | |
| Nil Ratan Sircar (NRS) Medical College | Kolkata | West Bengal | 700120 | India | Details | |
| TATA Memorial Centre | Kolkata | West Bengal | 700160 | India | Details | |
| Rajiv Gandhi Cancer Hospital | New Delhi | 110085 | India | Details | ||
| Barzilai Medical Center | Ashkelon | 7830604 | Israel | Details | ||
| Rambam Health Care Campus | Haifa | 3109601 | Israel | Details | ||
| Hadassah Medical Center | Jerusalem | Israel | Details | |||
| Rabin Medical Center | Petaẖ Tiqwa | 49100 | Israel | Details | ||
| Hospital Santa Maria of Terni | Terni | Umbria | 05100 | Italy | Details | |
| Azienda Ospedaliero-Universitaria Ospedali Riuniti | Ancona | 60131 | Italy | Details | ||
| ASST Papa Giovanni XXIII | Bergamo | 24127 | Italy | Details | ||
| Polyclinic S. Orsola-Malpighi, Department of Hematology, Oncology and Laboratory Medicine, Operative Unit of Hematology - Cavo | Bologna | 40138 | Italy | Details | ||
| University Hospital Careggi, Department of Hematology | Florence | 50134 | Italy | Details | ||
| University Hospital San Martino, IRCCA, Dept. of Integrative Cancer Therapies, Operative Unit of Clinical Hematology | Genoa | 16132 | Italy | Details | ||
| Hospital Niguerda Ca Granda, Department of Hematology and Oncology, Hematology Unit | Milan | 20162 | Italy | Details | ||
| Umberto I Polyclinic of Rome, Department of Cellular Biotechnology and Hematology, Hematology Center | Rome | 00161 | Italy | Details | ||
| University Hospital San Giovanni Battista of Turin | Turin | 10126 | Italy | Details | ||
| Jan Biziel University Hospital #2 in Bydgoszcz, Department of Hematology | Bydgoszcz | 85-168 | Poland | Details | ||
| Independent Public Healthcare Facility Municipal Hospital Group in Chorzow, Department of Hematology | Chorzow | 41-500 | Poland | Details | ||
| University Hospital in Krakow, Teaching Unit of the Hematology Department | Krakow | 31-501 | Poland | Details | ||
| Independent Public Teaching Hospital No.1 in Lublin, Department of Hematology-Oncology and Bone Marrow Transplantation | Lublin | 20-081 | Poland | Details | ||
| St. John of Dukla Oncology Center of Lublin, Department of Hematology | Lublin | 20-090 | Poland | Details | ||
| Military Institute of Medicine, Department of Internal Medicine and Hematology | Warsaw | 04-141 | Poland | Details | ||
| Nicolaus Copernicus Memorial Provincial Specialist Hospital in Lodz, Department of Hematology | Łódź | 93-513 | Poland | Details | ||
| Hyperclnical MedLife PDR Vulturului Brasov, Hematology Department | Braşov | 500366 | Romania | Details | ||
| Colentina Clinical Hospital, Department of Hematology | Bucharest | 020125 | Romania | Details | ||
| Bucharest University Emergency Hospital, Department of Hematology | Bucharest | 050098 | Romania | Details | ||
| S.P. Botkin City Clinical Hospital | Moscow | 125284 | Russian Federation | Details | ||
| N.A. Semashko Central Clinical Hospital #2 under OJSC Russian Railways | Moscow | 129128 | Russian Federation | Details | ||
| First I.P. Pavlov State Medical University of St. Petersburg | Saint Petersburg | 197022 | Russian Federation | Details | ||
| V.A. Almazov North-West Federal Medical Research Center, Chemotherapy of Oncohematology Diseases and Bone Marrow Transplantation Department #1 | Saint Petersburg | 197341 | Russian Federation | Details | ||
| Clinical Center of Serbia, Clinic of Hematology | Belgrade | 11000 | Serbia | Details | ||
| Institute of Oncology and Radiology of Serbia, Clinic of Medical Oncology | Belgrade | 11000 | Serbia | Details | ||
| Clinical Center Kragujevac, Clinic of Hematology | Kragujevac | 34 000 | Serbia | Details | ||
| Clinical Center Nis, Clinic of Hematology and Clinical Immunology | Nis | 18 000 | Serbia | Details | ||
| Clinical Center of Vojvodina, Clinic of Hematology | Novi Sad | 21 000 | Serbia | Details | ||
| University Hospital of the Canary Islands | La Laguna | Santa Cruz De Tenerife | 38320 | Spain | Details | |
| Catalan Institute of Oncology (ICO) Badalona | Badalona | 08916 | Spain | Details | ||
| University Hospital of Vall d'Hebron | Barcelona | 08035 | Spain | Details | ||
| University Hospital Infanta Leonor, Department of Hematology | Madrid | 28301 | Spain | Details | ||
| University Clinical Hospital of Salamanca, Department of Hematology | Salamanca | 37007 | Spain | Details | ||
| University Hospital Virgen del Rocio (HUVR) | Seville | 41013 | Spain | Details | ||
| Cherkasy Regional Oncology Center, Regional Treatment and Diagnostic Hematology Center, Department of Hematology | Cherkasy | 18009 | Ukraine | Details | ||
| City Clinical Hospital No.4 of Dnipro City Council, City hematology center | Dnipropetrovsk | Ukraine | Details | |||
| BMT Kiev Center | Kiev | Ukraine | Details | |||
| Kiev Cancer Institute | Kiev | Ukraine | Details | |||
| Institute of Blood Pathology and Transfusion Medicine, Department of Hematology with Laboratory Group | Lviv | 79044 | Ukraine | Details | ||
| Vinnytsia M.I. Pyrohov Regional Clinical Hospital, Department of Hematology | Vinnytsia | 21018 | Ukraine | Details | ||
| O.F. Herbachevskyi Regional Clinical Hospital, Hematology Department with Intensive Therapy Wards | Zhytomyr | 10008 | Ukraine | Details | ||
| Belfast Heatlh & Social Care Trust Belfast City Hospital | Belfast | Northern Ireland | BT9 7AB | United Kingdom | Details | |
| NHS Tayside Ninewells Hospital | Dundee | Scotland | DD1 9SY | United Kingdom | Details | |
| Cardiff & Vale University Health Board University Hospital of Wales | Cardiff | Wales | CF14 4XW | United Kingdom | Details | |
| University Hospitals Birmingham NHS Foundation Trust Queen Elizabeth Hospital | Birmingham | B15 2TH | United Kingdom | Details | ||
| The Leeds Teaching Hospitals NHS Trust St. James University Hospital | Leeds | LS9 7TF | United Kingdom | Details | ||
| University Hospitals of Leicester NHS Trust Royal Leicester Infirmary | Leicester | LE1 5WW | United Kingdom | Details | ||
| Royal Liverpool & Broadgreen University Hospital NHS Trust Royal Liverpool University Hospital | Liverpool | L7 8XP | United Kingdom | Details | ||
| London North West Healthcare NHS Trust Northwick Park Hospital | London | HA1 3UJ | United Kingdom | Details | ||
| University College London | London | NW3 2PF | United Kingdom | Details | ||
| King's College Hospital NHS Foundation Trust | London | SE5 9RS | United Kingdom | Details | ||
| Imperial College Healthcare NHS Trust Hammersmith Hospital | London | W12 0HS | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| Freeman Hospital | Newcastle Upon Tyne | NE7 7DN | United Kingdom | Details | ||
| The Royal Wolverhampton NHS Trust New Cross Hospital | Wolverhampton | WV10 0QP | United Kingdom | Details |