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| NCT ID | NCT03125902 |
| Title | A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC) (IMpassion131) |
| Acronym | IMpassion131 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | SVK | ROU | ITA | ISR | HRV | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BRA | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Stanford Cancer Center | Stanford | California | 94305-5820 | United States | Details | |
| Florida Cancer Specialists; Department of Oncology | Fort Myers | Florida | 33901-8101 | United States | Details | |
| Florida Cancer Specialist, North Region | Saint Petersburg | Florida | 33705 | United States | Details | |
| Northwest Georgia Oncology Centers PC - Marietta | Marietta | Georgia | 30060 | United States | Details | |
| HCA Midwest Health | Kansas City | Missouri | 64132 | United States | Details | |
| The Valley Hospital | Paramus | New Jersey | 07652 | United States | Details | |
| Magee-Woman's Hospital | Pittsburgh | Pennsylvania | 15213 | United States | Details | |
| Tennessee Oncology; Sarah Cannon Research Institute | Nashville | Tennessee | 37203 | United States | Details | |
| Centro Oncologico Riojano Integral (CORI) | La Rioja | F5300COE | Argentina | Details | ||
| Santa Casa de Misericordia de Salvador | Salvador | BA | 40050-410 | Brazil | Details | |
| Centro de Pesquisas Clinicas em Oncologia - CPCO | Cachoeiro de Itapemirim | ES | 29308-014 | Brazil | Details | |
| Hospital Araujo Jorge; Departamento de Ginecologia E Mama | Goiania | GO | 74605-070 | Brazil | Details | |
| Hospital Nossa Senhora da Conceicao | Porto Alegre | RS | 90040-373 | Brazil | Details | |
| Hospital Sao Lucas - PUCRS | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Hospital Perola Byington | Sao Paulo | SP | 01317-000 | Brazil | Details | |
| Tom Baker Cancer Centre-Calgary | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| Kingston General Hospital | Kingston | Ontario | K7L 2V7 | Canada | Details | |
| Grand River Hospital | Kitchener | Ontario | N2G 1G3 | Canada | Details | |
| London Regional Cancer Centre | London | Ontario | N6A 4L6 | Canada | Details | |
| Sunnybrook Odette Cancer Centre | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| McGill University; Glen Site; Oncology | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| Hopital du Saint Sacrement | Quebec City | Quebec | G1S 4L8 | Canada | Details | |
| Centre Hospitalier Universitaire de Sherbrooke - Hopital Fleurimont | Sherbrooke | Quebec | J1H 5N4 | Canada | Details | |
| Cancer Hospital Chinese Academy of Medical Sciences. | Beijing | 100021 | China | Details | ||
| Beijing Union Hospital | Beijing | 100730 | China | Details | ||
| West China Hospital, Sichuan University; Department of Breast | Chengdu | 610041 | China | Details | ||
| Sun Yat-sen Memorial Hospital | Guangzhou | 510000 | China | Details | ||
| Harbin Medical University Cancer Hospital | Harbin | 150081 | China | Details | ||
| Shandong Cancer Hospital | Jinan | 250117 | China | Details | ||
| Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University) | Nanjing City | 210029 | China | Details | ||
| Jiangsu Cancer Hospital | Nanjing City | 211100 | China | Details | ||
| Fudan University Shanghai Cancer Center | Shanghai City | 200120 | China | Details | ||
| Shanghai Jiao Tong University School of Medicine (SJTUSM) - Ruijin Hospital (GuangCi Hospital) | Shanghai | 200025 | China | Details | ||
| Liaoning cancer Hospital & Institute | Shenyang | 110042 | China | Details | ||
| Hebei Medical University Fourth Hospital;(Tumor Hospital of Hebei Province) | Shijiazhuang | 050035 | China | Details | ||
| Tianjin Medical University Cancer Institute & Hospital | Tianjin | 3000060 | China | Details | ||
| The Second Affiliated Hospital of Xi'an Jiao Tong University | Xi'an City | 710004 | China | Details | ||
| First Affiliated Hospital of Medical College of Xi'an Jiaotong University | Xi'an | 710061 | China | Details | ||
| Zhejiang Cancer Hospital | Zhejiang | 310022 | China | Details | ||
| Henan Cancer Hospital | Zhengzhou | 450008 | China | Details | ||
| Clinical Hospital Centre Zagreb | Zagreb | 10000 | Croatia | Details | ||
| Fakultni Nemocnice Hradec Kralove; Dept of Radiotherapy & Oncology | Hradec Kralove | 500 05 | Czechia | Details | ||
| Fakultni nemocnice Olomouc; Onkologicka klinika | Olomouc | 779 00 | Czechia | Details | ||
| Fakultni nemocnice Ostrava; Klinika onkologicka FNO a LF OU | Ostrava-Poruba | 70852 | Czechia | Details | ||
| Fakultni Poliklinika Vseobecne Fakultni Niemocnice; Onkologicka Klinika | Praha 2 | 128 08 | Czechia | Details | ||
| Clinique Sainte Catherine; Hopital De Semaine | Avignon | 84918 | France | Details | ||
| HOPITAL JEAN MINJOZ; Oncologie | Besancon | 25030 | France | Details | ||
| Polyclinique Bordeaux Nord Aquitaine | Bordeaux | 33300 | France | Details | ||
| Hopital Morvan | Brest | 29200 | France | Details | ||
| CHD Les Oudairies | La Roche Sur Yon | 85925 | France | Details | ||
| Centre Oscar Lambret; Senologie | Lille | 59020 | France | Details | ||
| Centre Leon Berard; Departement Oncologie Medicale | Lyon | 69373 | France | Details | ||
| Centre D'Oncologie de Gentilly; Oncology | Nancy | 54100 | France | Details | ||
| Hopital Caremeau; Hematologie Oncologie | Nimes | 30029 | France | Details | ||
| Hopital Tenon | Paris | 75020 | France | Details | ||
| Institut Curie; Oncologie Medicale | Paris | 75231 | France | Details | ||
| Hopital Saint Louis, Service D Oncologie Medicale | Paris | 75475 | France | Details | ||
| Ch Pitie Salpetriere; Oncologie Medicale | Paris | 75651 | France | Details | ||
| Centre Eugene Marquis; Service d'oncologie | Rennes | 35042 | France | Details | ||
| Centre Paul Strauss; Oncologie Medicale | Strasbourg | 67065 | France | Details | ||
| Institut Claudius Regaud; Departement Oncologie Medicale | Toulouse | 31059 | France | Details | ||
| Institut Gustave Roussy; Sitep | VILLEJUIF Cedex | 94805 | France | Details | ||
| Ambulantes Tumorzentrum Spandau; Dres. Benno Mohr und Uwe Peters | Berlin | 13581 | Germany | Details | ||
| Onkologische Schwerpunktpraxis Bielefeld | Bielefeld | 33604 | Germany | Details | ||
| Klinikum Essen-Mitte Ev. Huyssens-Stiftung / Knappschafts GmbH; Klinik für Senologie / Brustzentrum | Essen | 45136 | Germany | Details | ||
| HOPA im Struensee-Haus, Dres. Erik Engel, Wiebke Hollburg | Hamburg | 22767 | Germany | Details | ||
| Nationales Centrum für Tumorerkrankungen (NCT) ; Gyn. Onk. Frauenklinik; Uniklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
| St. Elisabeth Krankenhaus Köln GmbH; Gynäkologie und Geburtshilfe | Koeln | 50935 | Germany | Details | ||
| Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde | Mainz | 55131 | Germany | Details | ||
| OnkoNet Marburg GmbH | Marburg | 35037 | Germany | Details | ||
| Klinik & Poliklinik für Frauenheilkunde und Geburtshilfe, Campus Innenstadt | München | 80336 | Germany | Details | ||
| Gemeinschaftspraxis für Hämatologie und Onkologie | Münster | 48153 | Germany | Details | ||
| Klinikum Ernst von Bergmann; Frauenklinik | Potsdam | 14467 | Germany | Details | ||
| Dres. Helmut Forstbauer, Carsten Ziske und Kollegen; Onkologische Schwerpunktpraxis | Troisdorf | 53840 | Germany | Details | ||
| Universitätsklinik Tübingen; Frauenklinik | Tübingen | 72076 | Germany | Details | ||
| Anticancer Hospital Ag. Savas ; 2Nd Dept. of Oncology - Internal Medicine | Athens | 115 22 | Greece | Details | ||
| ARETAIEION UNIVERSITY HOSPITAL; oncology unit | Athens | 115 28 | Greece | Details | ||
| Agioi Anargyroi Cancer Hospital; 2Nd Oncology Dept. | Kifisia | 145 64 | Greece | Details | ||
| Papageorgiou General Hospital; Medical Oncology | Thessaloniki | 564 29 | Greece | Details | ||
| Yashoda Hospital | Hyderabad | Andhra Pradesh | 500082 | India | Details | |
| Dr. B L Kapur Memorial Hospital; BLK Cancer Centre | New Delhi | Delhi | 110005 | India | Details | |
| Indraprastha Apollo Hospitals | New Delhi | Delhi | 110076 | India | Details | |
| Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology | New Delhi | Delhi | 110085 | India | Details | |
| Max Super Speciality Hospital; Medical Oncology | North WEST Delhi | Delhi | 110088 | India | Details | |
| Manipal Hospital; Department of Oncology | Bangalore | Karnataka | 560017 | India | Details | |
| Tata Memorial Hospital; Dept of Medical Oncology | Mumbai | Maharashtra | 400012 | India | Details | |
| Jehangir Hospital | Pune | Maharashtra | 411001 | India | Details | |
| Apollo Speciality Hospital | Chennai | Tamil NADU | 600035 | India | Details | |
| Apollo Gleneagles Hospitals | Kolkata | WEST Bengal | 700054 | India | Details | |
| TATA Medical Centre; Medical Oncology | Kolkata | WEST Bengal | 700156 | India | Details | |
| MAX Balaji Hospital | Delhi | 1100092 | India | Details | ||
| Hadassah Ein Karem Hospital; Oncology Dept | Jerusalem | 9112000 | Israel | Details | ||
| Rabin MC; Davidof Center - Oncology Institute | Petach Tikva | 4941492 | Israel | Details | ||
| Sheba Medical Center | Ramat Gan | 5262100 | Israel | Details | ||
| Rambam Health Corporation; Oncology Institute | Rambam | 3525408 | Israel | Details | ||
| Kaplan Medical Center | Rehovot | 7610001 | Israel | Details | ||
| Tel Aviv Sourasky Medical Ctr; Oncology | Tel Aviv | 6423906 | Israel | Details | ||
| Assaf Harofeh; Oncology | Zerifin | 6093000 | Israel | Details | ||
| Fondazione Università G. D'Annunzio; Clinical Research Center (CRC); Centro Studi (CESI) | Chieti | Abruzzo | 66103 | Italy | Details | |
| Presidio Ospedaliero S. Giovanni Di Dio; U.O. Di Oncologia | Frattamaggiore | Campania | 80027 | Italy | Details | |
| Azienda Ospedaliera Universitaria Federico II | Napoli | Campania | 80131 | Italy | Details | |
| Istituto Nazionale Tumori Fondazione G. Pascale | Napoli | Campania | 80131 | Italy | Details | |
| Azienda Ospedaliero - Universitaria di Modena Policlinico | Modena | Emilia-Romagna | 41110 | Italy | Details | |
| Universita Campus Bio-Medico di Roma (UCBM) | Roma | Lazio | 00128 | Italy | Details | |
| IRCCS Istituto Regina Elena (IFO); Oncologia Medica B | Roma | Lazio | 00144 | Italy | Details | |
| Azienda Policlinico Umberto I | Roma | Lazio | 00161 | Italy | Details | |
| A.O. Universitaria S. Martino Di Genova | Genova | Liguria | 16132 | Italy | Details | |
| Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII) | Bergamo | Lombardia | 24127 | Italy | Details | |
| Asst Degli Spedali Civili Di Brescia | Brescia | Lombardia | 25123 | Italy | Details | |
| Hospital San Raffaele | Milano | Lombardia | 20132 | Italy | Details | |
| Fondazione IRCCS Istituto Nazionale dei Tumori | Milano | Lombardia | 20133 | Italy | Details | |
| IEO Istituto Europeo di Oncologia;Divisione Oncologia Medica | Milano | Lombardia | 20141 | Italy | Details | |
| IRCCS Istituto Clinico Humanitas; Oncologia | Rozzano (MI) | Lombardia | 20089 | Italy | Details | |
| Fondazione Del Piemonte Per L'oncologia IRCC Di Candiolo | Candiolo | Piemonte | 10060 | Italy | Details | |
| Ospedale S. Vincenzo; Oncologia Medica | Taormina | Sicilia | 98030 | Italy | Details | |
| Azienda Ospedaliero-Universitaria Careggi; SOD Radioterapia | Firenze | Toscana | 50134 | Italy | Details | |
| Ospedale Civile; Unita Operativa Di Oncologia Medica | Livorno | Toscana | 57100 | Italy | Details | |
| IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II | Padova | Veneto | 35128 | Italy | Details | |
| Gunma Prefectural Cancer Center | Gunma | 373-8550 | Japan | Details | ||
| Hiroshima City Hiroshima Citizens Hospital | Hiroshima | 730-8518 | Japan | Details | ||
| Sagara Hospital | Kagoshima | 892-0833 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Tokai University Hospital | Kanagawa | 259-1193 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Naha-nishi Clinic | Okinawa | 901-0154 | Japan | Details | ||
| Osaka International Cancer Institute | Osaka | 541-8567 | Japan | Details | ||
| Saitama Cancer Center | Saitama | 362-0806 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Tokyo | 135-8550 | Japan | Details | ||
| Centre Hospitalier Universitaire Mohamed VI; Oncologie-Hématologie | Marrakech | 40000 | Morocco | Details | ||
| Institut National D'oncologie Sidi Mohammed Ben Abdellah; Anatomopathologie | Rabat | 10000 | Morocco | Details | ||
| Prof. Dr. I. Chiricuta Institute of Oncology | Cluj Napoca | 400015 | Romania | Details | ||
| Centrul de Oncologie Sfantul Nectarie | Craiova | 200347 | Romania | Details | ||
| Russian Oncology Research Center n.a. N.N. Blokhin | Moscow | Moskovskaja Oblast | 115478 | Russian Federation | Details | |
| Petrov Research Inst. of Oncology | Sankt Petersburg | 197758 | Russian Federation | Details | ||
| King Fahad Specialist Hospital; Oncology | Dammam | 31444 | Saudi Arabia | Details | ||
| International Medical Center (IMC) | Jeddah | 21451 | Saudi Arabia | Details | ||
| King Fahad Medical City; Gastroentrology | Riyadh | 11525 | Saudi Arabia | Details | ||
| Narodny Onkologicky Ustav; Oddelenie klinickej onkologie A | Bratislava | 833 10 | Slovakia | Details | ||
| POKO Poprad; Department of Oncology | Poprad | 058 01 | Slovakia | Details | ||
| Wilgers Oncology Centre | Pretoria | 0001 | South Africa | Details | ||
| Private Oncology Centre | Pretoria | 0081 | South Africa | Details | ||
| Sandton Oncology Medical Group | Sandton | 2196 | South Africa | Details | ||
| Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia | A Coruña | LA Coruña | 15006 | Spain | Details | |
| Hospital Clínic i Provincial; Servicio de Hematología y Oncología | Barcelona | 08036 | Spain | Details | ||
| Hospital Universitario de Fuenlabrada; Servicio de Oncologia | Madrid | 28943 | Spain | Details | ||
| Hospital Universitario Virgen Macarena; Servicio de Oncologia | Sevilla | 41009 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Adana Baskent University Medical Faculty; Oncology | Adana | 01220 | Turkey | Details | ||
| Ankara Bilkent City Hospital | Ankara | 06490 | Turkey | Details | ||
| Uludag University Medical Faculty; Internal Medicine | Bursa | 16059 | Turkey | Details | ||
| Dicle Uni Medical Faculty; Internal Medicine | Diyarbakir | 10000 | Turkey | Details | ||
| Trakya Universitesi Tip Fakultesi, Medikal Onkoloji Bilim Dali, Balkan Yerleskesi | Edirne | 22030 | Turkey | Details | ||
| Izmir Ataturk Training and Research Hospital | Izmir | 35965 | Turkey | Details | ||
| Kocaeli University Faculty of Medicine; Medical oncology | Izmit | 31380 | Turkey | Details | ||
| Goztepe Prof.Dr. Suleyman Yalcin City Hospital; Clinical Oncology | Kadiköy | 34722 | Turkey | Details | ||
| Guys and St Thomas NHS Foundation Trust, Guys Hospital | London | SE1 9RT | United Kingdom | Details | ||
| Christie Hospital | Manchester | M20 3BG | United Kingdom | Details | ||
| Mount Vernon Cancer Centre | Northwood | HA6 2RN | United Kingdom | Details | ||
| K hospital | Hanoi | 100000 | Vietnam | Details | ||
| Hochiminh city oncology hospital | Hochiminh city | 700000 | Vietnam | Details |