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| NCT ID | NCT03157128 |
| Title | A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001) |
| Acronym | LIBRETTO-001 |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | Yes |
| Sponsors | Loxo Oncology, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | child | senior |
| Covered Countries | USA | ITA | ISR | GBR | FRA | ESP | DNK | DEU | CHE | CAN | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic of Scottsdale | Scottsdale | Arizona | 85259 | United States | Details | |
| City of Hope National Medical Center | Duarte | California | 91010-0269 | United States | Details | |
| University of California - San Diego | La Jolla | California | 92161 | United States | Details | |
| UCLA Medical Center | Los Angeles | California | 90095 | United States | Details | |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | United States | Details | |
| Irvine Medical Center | Orange | California | 92868 | United States | Details | |
| UCSF Medical Center at Mission Bay | San Francisco | California | 94115 | United States | Details | |
| Kaiser Permanente | Santa Clara | California | 95051 | United States | Details | |
| Kaiser Permanente Medical Center | Vallejo | California | 94589 | United States | Details | |
| Sarah Cannon Research Institute at HealthOne | Denver | Colorado | 80218 | United States | Details | |
| Yale Cancer Center | New Haven | Connecticut | 06510 | United States | Details | |
| Johns Hopkins University | Washington | District of Columbia | 20016 | United States | Details | |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | United States | Details | |
| Memorial Hospital Pembroke | Pembroke | Florida | 33028 | United States | Details | |
| Emory University | Atlanta | Georgia | 30322 | United States | Details | |
| University of Chicago Medicine-Comprehensive Cancer Center | Chicago | Illinois | 60637 | United States | Details | |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | United States | Details | |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | United States | Details | |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | United States | Details | |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Michigan | Ann Arbor | Michigan | 48109 | United States | Details | |
| START Midwest | Grand Rapids | Michigan | 49546 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University Medical School | Saint Louis | Missouri | 63110 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263-0002 | United States | Details | |
| NYU Langone | New York | New York | 10016 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| University of North Carolina | Chapel Hill | North Carolina | 27599-7305 | United States | Details | |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | United States | Details | |
| Ohio State University Hospital | Columbus | Ohio | 43210 | United States | Details | |
| Oregon Health and Science University | Portland | Oregon | 97201 | United States | Details | |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | United States | Details | |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | United States | Details | |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-6307 | United States | Details | |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-9063 | United States | Details | |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| USO-Virginia Cancer Specialists, PC | Fairfax | Virginia | 22031 | United States | Details | |
| University of Wisconsin-Madison Hospital and Health Clinic | Madison | Wisconsin | 53792 | United States | Details | |
| Royal North Shore Hospital | St. Leonards | New South Wales | 2065 | Australia | Details | |
| Peter MacCallum Cancer Centre | Melbourne | Victoria | 3000 | Australia | Details | |
| BC Cancer Vancouver | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Rigshospitalet | Copenhagen | København Ø | 2100 | Denmark | Details | |
| Hôpital Européen Georges Pompidou | Paris | Cedex 15 | 75908 | France | Details | |
| Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest | Bordeaux | 33076 | France | Details | ||
| Centre Leon Berard | Lyon Cedex 08 | 69373 | France | Details | ||
| APHM Hôpital de la Timone | Marseille | 13385 | France | Details | ||
| Institut du Cancer de Montpellier - Val d'aurelle | Montpellier Cedex 5 | 34298 | France | Details | ||
| Gustave Roussy | Villejuif Cedex | 94805 | France | Details | ||
| Universitätsklinikum Würzburg A. ö. R. | Würzburg | Bayern | 97080 | Germany | Details | |
| Universitätsklinikum Köln | Köln | Nordrhein-Westfalen | 50937 | Germany | Details | |
| Prince of Wales Hospital | Hong Kong | Shatin, New Territories | Hong Kong | Details | ||
| Sheba Medical Center | Tel Hashomer | Ramat Gan | 5265601 | Israel | Details | |
| Shaare Zedek Medical Center | Jerusalem | Yerushalayim | 9103102 | Israel | Details | |
| Soroka Medical Center - Pediatric Outpatient Clinic | Beer-Sheva | 8410101 | Israel | Details | ||
| Hadassah Medical Center | Jerusalem | 91120 | Israel | Details | ||
| Istituto Nazionale dei Tumori | Milano | Lombardie | 20133 | Italy | Details | |
| Nagoya University Hospital | Nagoya | Aichi | 466-8560 | Japan | Details | |
| National Cancer Center Hospital East | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| Hokkaido University Hospital | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Hyogo Cancer Center | Akashi | Hyogo | 673-8558 | Japan | Details | |
| Kanazawa University Hospital | Kanazawa | Ishikawa | 920-8641 | Japan | Details | |
| Kindai University Hospital | Osaka Sayama-shi | Osaka | 589 8511 | Japan | Details | |
| Tominaga Hospital | Nagaizumi-cho,Sunto-gun | Shizuoka | 411-8777 | Japan | Details | |
| National Cancer Center Hospital | Chuo-ku | Tokyo | 104-0045 | Japan | Details | |
| Japanese Foundation for Cancer Research | Koto | Tokyo | 135-8550 | Japan | Details | |
| Tottori University Hospital | Yonago | Tottori | 683-8504 | Japan | Details | |
| National Hospital Organization Kyushu Cancer Center | Fukuoka | 811-1395 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| Osaka City General Hospital | Osaka | 534-0021 | Japan | Details | ||
| National Cancer Center | Goyang-si | Gyeonggi-do | 10408 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | Seongnam | Kyǒnggi-do | 13620 | Korea, Republic of | Details | |
| Asan Medical Center | Seoul | Seoul-teukbyeolsi [Seoul] | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center | Seoul | Seoul-teukbyeolsi [Seoul] | 06351 | Korea, Republic of | Details | |
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| National Cancer Centre Singapore | Singapore | 169610 | Singapore | Details | ||
| Hospital Universitari Vall d'Hebron | Barcelona | Barcelona [Barcelona] | 8035 | Spain | Details | |
| Hospital Universitario Fundación Jiménez Díaz | Madrid | 28040 | Spain | Details | ||
| Hospital Madrid Norte Sanchinarro | Madrid | 28050 | Spain | Details | ||
| Kantonsspital Luzern | Luzern 16 | Luzern | 6000 | Switzerland | Details | |
| Taichung Veterans General Hospital | Taichung | 40705, ROC | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 10002 | Taiwan | Details | ||
| Royal Marsden Hospital | Sutton | Surrey | SM2 5PT | United Kingdom | Details |