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| NCT ID | NCT03337724 |
| Title | A Study of Ipatasertib in Combination With Paclitaxel as a Treatment for Participants With PIK3CA/AKT1/PTEN-Altered, Locally Advanced or Metastatic, Triple-Negative Breast Cancer or Hormone Receptor-Positive, HER2-Negative Breast Cancer (IPATunity130) |
| Acronym | IPATunity130 |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SVN | POL | ITA | HUN | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| UCSD Moores Cancer Center | La Jolla | California | 92093 | United States | Details | |
| USC Norris Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| USC Norris Cancer Center; USC Oncology Hematology Newport Beach | Newport Beach | California | 92663 | United States | Details | |
| Kaiser Permanente - Oakland | Oakland | California | 94611 | United States | Details | |
| Kaiser Permanente - Roseville | Roseville | California | 95661 | United States | Details | |
| UC Davis; Comprehensive Cancer Center | Sacramento | California | 95817 | United States | Details | |
| Kaiser Permanente Sacramento Medical Center | Sacramento | California | 95825 | United States | Details | |
| Kaiser Permanente - San Francisco (2238 Geary) | San Francisco | California | 94115 | United States | Details | |
| UCSF Comprehensive Cancer Ctr | San Francisco | California | 94158 | United States | Details | |
| K. Permanente - San Jose | San Jose | California | 95119 | United States | Details | |
| Kaiser Permanente - San Leandro | San Leandro | California | 94577 | United States | Details | |
| K. Permanente - Santa Clara | Santa Clara | California | 95051 | United States | Details | |
| Kaiser Permanente - South San Francisco | South San Francisco | California | 94080 | United States | Details | |
| Kaiser Permanente - Vallejo | Vallejo | California | 94589 | United States | Details | |
| K. Permanente - Walnut Creek | Walnut Creek | California | 94596 | United States | Details | |
| Memorial Regional Hospital | Hollywood | Florida | 33021 | United States | Details | |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | United States | Details | |
| UF Health Cancer Center at Orlando Health | Orlando | Florida | 32824 | United States | Details | |
| Memorial Hospital West | Pembroke Pines | Florida | 33028 | United States | Details | |
| University of Maryland | Baltimore | Maryland | 21201 | United States | Details | |
| Mercy Medical Center | Baltimore | Maryland | 21202 | United States | Details | |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| Memorial Sloan Kettering Cancer Center at Westchester | Harrison | New York | 10604 | United States | Details | |
| Memorial Sloan Kettering | New York | New York | 10065 | United States | Details | |
| West Clinic | Germantown | Tennessee | 38138 | United States | Details | |
| Texas Oncology, P.A. | Dallas | Texas | 75246 | United States | Details | |
| UT Southwestern Medical Center; Simmons Comprehensive Cancer Center, Simmons Pharmacy | Dallas | Texas | 75390 | United States | Details | |
| Oncology Consultants PA | Houston | Texas | 77030 | United States | Details | |
| Fundación CENIT para la Investigación en Neurociencias | Buenos Aires | C1125ABD | Argentina | Details | ||
| Hosp Provincial D. Centenarios; Oncology Dept | Rosario | S2002KDS | Argentina | Details | ||
| Chris O'Brien Lifehouse | Camperdown | New South Wales | 2050 | Australia | Details | |
| Calvary Mater Newcastle; Medical Oncology | Waratah | New South Wales | 2298 | Australia | Details | |
| Westmead Hospital; Medical Oncology | Wentworthville | New South Wales | 2145 | Australia | Details | |
| Mater Hospital; Cancer Services | South Brisbane | Queensland | 4101 | Australia | Details | |
| Cabrini Medical Centre; Oncology | Malvern | Victoria | 3144 | Australia | Details | |
| Fiona Stanley Hospital; FSH Cancer Centre Clinical Trials Unit | Bull Creek | Western Australia | 6149 | Australia | Details | |
| Cliniques Universitaires St-Luc | Bruxelles | 1200 | Belgium | Details | ||
| GHdC Site Notre Dame | Charleroi | 6000 | Belgium | Details | ||
| UZ Leuven Gasthuisberg | Leuven | 3000 | Belgium | Details | ||
| Santa Casa de Misericordia de Salvador | Salvador | BA | 40050-410 | Brazil | Details | |
| Hospital Araujo Jorge; Departamento de Ginecologia E Mama | Goiania | GO | 74605-070 | Brazil | Details | |
| Hospital do Câncer de Londrina | Londrina | PR | 86015-520 | Brazil | Details | |
| Instituto Nacional de Cancer - INCa; Oncologia | Rio de Janeiro | RJ | 20560-120 | Brazil | Details | |
| Hospital Sao Lucas - PUCRS | Porto Alegre | RS | 90610-000 | Brazil | Details | |
| Hospital Nossa Senhora da Conceicao | Porto Alegre | RS | 91350-200 | Brazil | Details | |
| Faculdade de Medicina do ABC - FMABC | Santo Andre | SP | 09060-650 | Brazil | Details | |
| Hospital Perola Byington | Sao Paulo | SP | 01317-000 | Brazil | Details | |
| British Columbia Cancer Agency (Bcca) - Vancouver Cancer Centre | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Jewish General Hospital | Montreal | Quebec | H3T 1E2 | Canada | Details | |
| Sociedad de Investigaciones Medicas Ltda (SIM) | Temuco | 4800827 | Chile | Details | ||
| Clinica CIMCA | San José | 10103 | Costa Rica | Details | ||
| ICIMED Instituto de Investigación en Ciencias Médicas | San José | 10108 | Costa Rica | Details | ||
| Masaryk?v onkologický ústav; Klinika komplexní onkologické pé?e | Brno | 656 53 | Czechia | Details | ||
| Fakultni nemocnice Olomouc; Onkologicka klinika | Olomouc | 779 00 | Czechia | Details | ||
| CHU Besançon - Hôpital Jean Minjoz | Besançon Cedex | 25030 | France | Details | ||
| Polyclinique Bordeaux Nord Aquitaine | Bordeaux | 33300 | France | Details | ||
| Centre Georges Francois Leclerc; Oncologie 3 | Dijon | 21079 | France | Details | ||
| ICM; Medecine B3 | Montpellier cedex 5 | 34298 | France | Details | ||
| Centre Catherine De Sienne | Nantes | 44202 | France | Details | ||
| APHP - Hospital Saint Louis | Paris | 75475 | France | Details | ||
| Institut Jean Godinot; Oncologie Medicale | Reims CEDEX | 51056 | France | Details | ||
| Onkologische Schwerpunktpraxis Kurfürstendamm | Berlin | 10707 | Germany | Details | ||
| Praxis für Interdisziplinäre Onkologie und Hämatologie GbR | Freiburg | 79110 | Germany | Details | ||
| Universitätsklinikum Hamburg-Eppendorf; Frauenklinik | Hamburg | 20246 | Germany | Details | ||
| Universitätsklinikum des Saarlandes; Klinik f. Frauenheilkunden und Geburtshilfe | Homburg/Saar | 66424 | Germany | Details | ||
| Praxis Dr.med. Katja Ziegler-Löhr | Köln | 50679 | Germany | Details | ||
| Dres. Andreas Köhler und Roswitha Fuchs | Langen | 63225 | Germany | Details | ||
| Mühlenkreiskliniken; Johannes Wesling Klinikum Minden; Klinik für Frauenheilkunde und Geburtshilfe | Minden | 32429 | Germany | Details | ||
| Oncologianova GmbH - Gesellschaft für Innovationen in der Onkologie | Recklinghausen | 45659 | Germany | Details | ||
| Universitätsfrauen- und Poliklinik am Klinikum Suedstadt | Rostock | 18059 | Germany | Details | ||
| Universitätsklinikum Würzburg; Frauenklinik | Würzburg | 97080 | Germany | Details | ||
| Anticancer Hospital Ag Savas; 1St Dept of Internal Medicine | Athens | 115 22 | Greece | Details | ||
| Agioi Anargyroi; 3Rd Dept. of Medical Oncology | Athens | 145 64 | Greece | Details | ||
| Euromedical General Clinic of Thessaloniki; Oncology Department | Thessaloniki | 546 45 | Greece | Details | ||
| Orszagos Onkologial Intezet; Onkologiai Osztaly X | Budapest | 1122 | Hungary | Details | ||
| Borsod-Abauj-Zemplen Megyei Korhaz Es Egyetemi Oktato Korhaz; Onkologiai Osztaly | Miskolc | 3501 | Hungary | Details | ||
| Szegedi Tudomanyegyetem, AOK, Szent-Gyorgyi Albert Klinikai Kozpont, Onkoterapias Klinika | Szeged | 6720 | Hungary | Details | ||
| Hetenyi Geza County Hospital; Onkologiai Kozpont | Szolnok | 5004 | Hungary | Details | ||
| Zala County Hospital ICU | Zalaegerszeg | 8900 | Hungary | Details | ||
| Indraprastha Apollo Hospitals | New Delhi | Delhi | 110076 | India | Details | |
| Rajiv Gandhi Cancer Inst.&Research Center; Medical Oncology | New Delhi | Delhi | 110085 | India | Details | |
| Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica | Napoli | Campania | 80131 | Italy | Details | |
| Azienda Ospedaliero-Universitaria S.Orsola-Malpighi; Unità Operativa Oncologia Medica | Bologna | Emilia-Romagna | 40138 | Italy | Details | |
| Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica | Aviano | Friuli-Venezia Giulia | 33081 | Italy | Details | |
| Ospedale Santa Maria Annunziata; Oncologia | Bagno a Ripoli | Toscana | 50012 | Italy | Details | |
| IOV - Istituto Oncologico Veneto - IRCCS; Oncologia Medica II | Padova | Veneto | 35128 | Italy | Details | |
| Aichi Cancer Center Hospital | Aichi | 464-8681 | Japan | Details | ||
| National Cancer Center Hospital East | Chiba | 277-8577 | Japan | Details | ||
| National Hospital Organization Kyushu Cancer Center;Breast Oncology | Fukuoka | 811-1395 | Japan | Details | ||
| Fukushima Medical University Hospital | Fukushima | 960-1295 | Japan | Details | ||
| Hyogo Medical University Hospital | Hyogo | 663-8501 | Japan | Details | ||
| St. Marianna University Hospital | Kanagawa | 216-8511 | Japan | Details | ||
| Kanagawa Cancer Center | Kanagawa | 241-8515 | Japan | Details | ||
| Tokai University Hospital | Kanagawa | 259-1193 | Japan | Details | ||
| Kumamoto Shinto General Hospital | Kumamoto | 862-8655 | Japan | Details | ||
| Niigata Cancer Center Hospital | Niigata | 951-8566 | Japan | Details | ||
| Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
| National Hospital Organization Osaka National Hospital | Osaka | 540-0006 | Japan | Details | ||
| Kinki University Hospital, Faculty of Medicine; Surgery | Osaka | 589-8511 | Japan | Details | ||
| Saitama Cancer Center, Breast Oncology | Saitama | 362-0806 | Japan | Details | ||
| Shizuoka Cancer Center | Shizuoka | 411-8777 | Japan | Details | ||
| National Cancer Center Hospital | Tokyo | 104-0045 | Japan | Details | ||
| St. Luke's International Hospital | Tokyo | 104-8560 | Japan | Details | ||
| The Cancer Institute Hospital of JFCR | Tokyo | 135-8550 | Japan | Details | ||
| Showa University Hospital; Breast Surgery | Tokyo | 142-8666 | Japan | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Inha University Hospital | Incheon | 22332 | Korea, Republic of | Details | ||
| Seoul National University Bundang Hospital | Seongnam-si | 463-707 | Korea, Republic of | Details | ||
| Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital, Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| Centro Medico Dalinde | Cdmx | Mexico CITY (federal District) | 06760 | Mexico | Details | |
| Centro Médico Zambrano Hellion | Monterrey | Nuevo LEON | 66278 | Mexico | Details | |
| Merida | Investigacion Clinica | Mérida | Yucatan | 97125 | Mexico | Details | |
| CENEIT Oncologicos; DENTRO DE CONDOMINIO SAN FRANCISCO | Mexico City | 03100 | Mexico | Details | ||
| Clinical Hospital; Oncology Department | Bitola | 7000 | North Macedonia | Details | ||
| PHI University Clinic of Radiotherapy and Oncology; Breast malignancy | Skopje | 1000 | North Macedonia | Details | ||
| PHI University Clinic of Radiotherapy and Oncology; Malignant diseases of thorax | Skopje | 1000 | North Macedonia | Details | ||
| Centro Medico Monte Carmelo | Arequipa | 04001 | Peru | Details | ||
| Hospital Daniel Alcides Carrion | Callao | 07021 | Peru | Details | ||
| Clínica San Gabriel; Unidad de Investigación Oncológica de la Clínica San Gabriel | Lima | 15088 | Peru | Details | ||
| Hospital Nacional Cayetano Heredia; Ocología; Servicio de Hematología Oncología Médica | Lima | 15102 | Peru | Details | ||
| Oncosalud Sac; Oncología | Lima | 41 | Peru | Details | ||
| Instituto Nacional de Enfermedades Neoplasicas | Lima | Lima 34 | Peru | Details | ||
| Clinica Ricardo Palma | San Isidro | Lima 27 | Peru | Details | ||
| Instituto Regional de Enfermedades Neoplasicas - IREN Norte | Trujillo | 13014 | Peru | Details | ||
| Instyt. Centrum Zdrowia Matki Polki; Klinika Chirurgii Onk. Chorób Piersi z Podod. Onko Klinicznej | ?ód? | 93-338 | Poland | Details | ||
| Narodowy Inst.Onkol.im.Sklodowskiej-Curie Panstw.Inst.Bad Gliwice; III Klin. Radioter. i Chemioter. | Gliwice | 44-101 | Poland | Details | ||
| Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie; Klinika Nowotworow Piersi i Chirurgii Rekonstr | Warszawa | 02-781 | Poland | Details | ||
| Arkhangelsk Regional Clinical Oncology Dispensary | Arkhangelsk | Arhangelsk | 163045 | Russian Federation | Details | |
| Moscow City Oncology Hospital #62 | Moscovskaya Oblast | Moskovskaja Oblast | 143423 | Russian Federation | Details | |
| Federal State Institution, Moscow Research Oncology Institute n.a. P.A. Hertzen; Oncourology | Moscow | Moskovskaja Oblast | 125284 | Russian Federation | Details | |
| Blokhin Cancer Research Center; Combined Treatment | Moskva | Moskovskaja Oblast | 115478 | Russian Federation | Details | |
| FSI Rostov research oncological institute of MoH and SD of RF; PAD | Rostov-on-Don | Rostov | 344037 | Russian Federation | Details | |
| S-Pb clinical scientific practical center of specialized kinds of medical care (oncological) | Saint-Petersburg | Sankt Petersburg | 197758 | Russian Federation | Details | |
| Clinical Oncology Dispensary of Ministry of Health of Tatarstan | Kazan | Tatarstan | 420029 | Russian Federation | Details | |
| Ivanovo Regional Oncology Dispensary | Ivanovo | 153040 | Russian Federation | Details | ||
| SBIH Kaluga Region Clinical Oncology Dispensary | Kaluga | 248007 | Russian Federation | Details | ||
| National University Hospital; National University Cancer Institute, Singapore (NCIS) | Singapore | 119228 | Singapore | Details | ||
| National Cancer Centre; Medical Oncology | Singapore | 168583 | Singapore | Details | ||
| Institute of Oncology Ljubljana | Ljubljana | 1000 | Slovenia | Details | ||
| Medical Oncology Centre of Rosebank; Oncology | Johannesburg | 2196 | South Africa | Details | ||
| Hospital Provincial de Castellon; Servicio de Oncologia | Castellon de La Plana | Castellon | 12002 | Spain | Details | |
| Hospital Universitario Reina Sofia; Servicio de Oncologia | Córdoba | Cordoba | 14004 | Spain | Details | |
| Complejo Hospitalario Universitario de Santiago (CHUS) ; Servicio de Oncologia | Santiago de Compostela | LA Coruña | 15706 | Spain | Details | |
| Hospital Universitario Puerta de Hierro; Servicio de Oncologia | Majadahonda | Madrid | 28222 | Spain | Details | |
| Hospital del Mar; Servicio de Oncologia | Barcelona | 08003 | Spain | Details | ||
| Vall d?Hebron Institute of Oncology (VHIO), Barcelona | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic Barcelona; Servicio de oncologia | Barcelona | 08036 | Spain | Details | ||
| Hospital de Donostia; Servicio de Oncologia | Guipuzcoa | 20014 | Spain | Details | ||
| Hospital Ramon y Cajal; Servicio de Oncologia | Madrid | 28034 | Spain | Details | ||
| HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia | Madrid | 28050 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio; Servicio de Oncologia | Sevilla | 41013 | Spain | Details | ||
| Hospital Clinico Universitario; Oncologia | Valencia | 46010 | Spain | Details | ||
| Chi Mei Medical Center Liou Ying Campus | Liuying Township | 736 | Taiwan | Details | ||
| Koo Foundation Sun Yat-Sen Cancer Center; Hemato-Oncology | Taipei City | 11259 | Taiwan | Details | ||
| VETERANS GENERAL HOSPITAL; Department of General Surgery | Taipei | 00112 | Taiwan | Details | ||
| National Taiwan Uni Hospital; General Surgery | Taipei | 100 | Taiwan | Details | ||
| Ankara Bilkent City Hospital | Ankara | 06490 | Turkey | Details | ||
| Dicle Uni Medical Faculty; Internal Medicine | Diyarbakir | 10000 | Turkey | Details | ||
| Medipol University Medical Faculty; Oncology Department | Istanbul | 34214 | Turkey | Details | ||
| Prof. Dr. Cemil Tascioglu City Hospital; Med Onc | Istanbul | 34384 | Turkey | Details | ||
| Katip Celebi University Ataturk Training and Research Hospital; Oncology | Izmir | 35360 | Turkey | Details | ||
| Sakarya University Medical School; Medical Oncology | Sakarya | 54100 | Turkey | Details | ||
| Chemotherapy SI Dnipropetrovsk MA of MOHU | Dnipropetrovsk | 49102 | Ukraine | Details | ||
| Kyiv City Clinical Oncological Center, Day Hospital Department for Oncological patients | Kiev | 03115 | Ukraine | Details | ||
| National Cancer Institute MOH of Ukraine | Kiev | 36022 | Ukraine | Details | ||
| Lviv State Oncological Regional Treatment and Diagnostic Center | Lviv | 79031 | Ukraine | Details | ||
| Velindre Cancer Centre | Cardiff | CF14 2TL | United Kingdom | Details | ||
| University Hospital coventry; Oncology Department | Coventry | CV2 2DX | United Kingdom | Details | ||
| The Beatson West of Scotland Cancer Centre; Cancer Clinical Trials Unit | Glasgow | G12 0YN | United Kingdom | Details | ||
| Royal Marsden Hospital - London | London | SW3 6JJ | United Kingdom | Details | ||
| Derriford Hospital | Plymouth | PL6 8BT | United Kingdom | Details | ||
| Royal Stoke University Hospital | Stoke-on-Trent | ST4 6QG | United Kingdom | Details | ||
| Royal Marsden Hospital; Dept of Medical Oncology | Sutton | SM2 5PT | United Kingdom | Details |