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| NCT ID | NCT03465722 |
| Title | (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Blueprint Medicines Corporation |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | SWE | POL | NLD | ITA | HUN | GBR | FRA | ESP | DEU | CZE | CAN | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic Cancer Center | Phoenix | Arizona | 85054 | United States | Details | |
| UCLA Hematology/Oncology - Santa Monica | Santa Monica | California | 90404 | United States | Details | |
| University of Colorado Hospital | Aurora | Colorado | 80045 | United States | Details | |
| Rocky Mountain Cancer Centers | Boulder | Colorado | 80303 | United States | Details | |
| Washington Hospital Center - Oncology and Hematology | Washington | District of Columbia | 20010 | United States | Details | |
| Mayo Clinic Cancer Center | Jacksonville | Florida | 32224 | United States | Details | |
| University of Miami | Miami | Florida | 33146 | United States | Details | |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States | Details | |
| Northside Hospital | Atlanta | Georgia | 30341 | United States | Details | |
| Northwestern Medicine | Chicago | Illinois | 60611 | United States | Details | |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | United States | Details | |
| University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | 48109 | United States | Details | |
| Mayo Clinic Cancer Center | Rochester | Minnesota | 55905 | United States | Details | |
| Washington University in Saint Louis | Saint Louis | Missouri | 63130 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Ohio State University | Columbus | Ohio | 43210 | United States | Details | |
| OHSU - Knight Cancer Institute | Portland | Oregon | 97239 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
| Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| USO - Texas Oncology | Dallas | Texas | 75246 | United States | Details | |
| Texas Oncology - Denton South | Denton | Texas | 76210 | United States | Details | |
| University of Texas MD Anderson | Houston | Texas | 77030 | United States | Details | |
| Texas Oncology - Waco | Waco | Texas | 76712 | United States | Details | |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | United States | Details | |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | United States | Details | |
| Summit Cancer Centers | Spokane | Washington | 99216 | United States | Details | |
| Medical College of Wisconsin - Froedtert Hospital | Milwaukee | Wisconsin | 53226 | United States | Details | |
| Flinders Medical Center | Adelaide | Australia | Details | |||
| Monash Health | Clayton | Australia | Details | |||
| The Canberra Hospital | Garran | Australia | Details | |||
| AKH, Klinik f. Innere Med. I, Onkologie | Wien | Austria | Details | |||
| Institut Jules Bordet | Brussels | Belgium | Details | |||
| Leuven Cancer Institute | Leuven | Belgium | Details | |||
| Cross Cancer Institute | Edmonton | Alberta | Canada | Details | ||
| University Health Network | Toronto | Ontario | M5G 1L7 | Canada | Details | |
| Jewish General Hospital | Montréal | Canada | Details | |||
| Beijing Cancer Hospital | Beijing | China | Details | |||
| Chinese PLA General Hospital | Beijing | China | Details | |||
| West China Hospital Sichuan University | Chengdu | China | Details | |||
| The First Affiliated Hospital of Chongqing Medical University | Chongqing | China | Details | |||
| Fujian Medical University Union Hospital | Fuzhou | China | Details | |||
| The First Affiliated Hospital of Sun Yat-sen University | Guangzhou | China | Details | |||
| The Sixth Affiliated Hospital of Sun Yat-Sen University | Guangzhou | China | Details | |||
| The First Affiliated Hospital, Zhejiang University | Hangzhou | China | Details | |||
| Harbin Medical University Cancer Hospital | Harbin | China | Details | |||
| The First Affiliated Hospital of Nanchang Medical University | Nanchang | China | Details | |||
| Guangxi Medical University Affiliated Tumor Hospital & Oncology Medical College | Nanning | China | Details | |||
| The Affiliated Hospital of Qingdao University | Qingdao | China | Details | |||
| Fudan University Shanghai Cancer Center | Shanghai | China | Details | |||
| Fudan University Zhongshan Hospital | Shanghai | China | Details | |||
| Shanghai Jiaotong University School of Medicine, Renji Hospital | Shanghai | China | Details | |||
| Liaoning Cancer Hospital & Institute | Shenyang | China | Details | |||
| Tianjin Cancer Hospital | Tianjin | China | Details | |||
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | Wuhan | China | Details | |||
| Affiliated Cancer Hospital of Xinjiang Medical University | Ürümqi | China | Details | |||
| Onkologická klinika Fakultní nemocnice Olomouc | Olomouc | Czechia | Details | |||
| Fackultni Nemocnice v Motole | Praha | Czechia | Details | |||
| Institut Bergonié | Bordeaux | France | Details | |||
| Centre Oscar Lambret | Lille | France | Details | |||
| UNICANCER - Lyon, Centre Léon-Bérard | Lyon | 69008 | France | Details | ||
| Institute Paoli Calmettes | Marseille | France | Details | |||
| La Timone University Hospital | Marseille | France | Details | |||
| Institut Curie | Paris | France | Details | |||
| Centre Rene Gauducheau | Saint-Herblain | France | Details | |||
| Gustave Roussy Cancer Campus | Villejuif | France | Details | |||
| HELIOS Klinikum Bad Saarow | Bad Saarow | Germany | Details | |||
| HELIOS Klinikum Berlin-Buch | Berlin | Germany | Details | |||
| Medizinische Fakultät Carl Gustav Carus | Dresden | Germany | Details | |||
| Universitaetsklindum Essen | Essen | Germany | Details | |||
| Universitätsklinikum Frankfurt | Frankfurt | Germany | Details | |||
| Studienzentrale GbR Lübecker Onkologische Schwerpunktpraxis Dres. med. Uthgenannt | Lubeck | Germany | Details | |||
| Rupercht-Karls-Universitaet Heidelberg | Mannheim | Germany | Details | |||
| Fovarosi Onkormanyzat Szent Laszlo Korhaz | Budapest | Hungary | Details | |||
| Magyar Honvédség Egészségügyi Központ Onkológiai Osztály | Budapest | Hungary | Details | |||
| Medical Oncology University Debrecen | Debrecen | Hungary | Details | |||
| University of Pécs | Pécs | Hungary | Details | |||
| Azienda Ospedaliero Universitaria Sant'Orsola Malpighi | Bologna | Italy | Details | |||
| Candiolo Cancer Institute - FPO, IRCCS | Candiolo | Italy | Details | |||
| AOUC Azienda Ospedaliero - Universitaria Careggi | Firenze | Italy | Details | |||
| Fondazione IRCCS Istituto Nazionale dei Tumori Milano | Milano | Italy | Details | |||
| Istituto Europeo di Oncologia | Milano | Italy | Details | |||
| Universita degli Studi di Palermo - Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone | Palermo | Italy | Details | |||
| Campus Bio-Medico - Oncology Medica | Roma | Italy | Details | |||
| Ajou University Hospital | Suwon-si | Gyeong Gi-do | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | Korea, Republic of | Details | |||
| Samsung Medical Center | Seoul | Korea, Republic of | Details | |||
| Seoul National University Hospital | Seoul | Korea, Republic of | Details | |||
| Severance Hospital | Seoul | Korea, Republic of | Details | |||
| Nederlands Kanker Instituut - Antoni Van Leeuwenhoek Ziekenhuis | Amsterdam | Netherlands | Details | |||
| Radboud University Medical Center | Nijmegen | Netherlands | Details | |||
| Erasmus Medical Center | Rotterdam | Netherlands | Details | |||
| Sanodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwesytecki w Krakowie, Oddzial Kliniczny Onkologii | Kraków | Poland | Details | |||
| Samodzielny Publiczny Zaklad Opieki Zdrowotnej MSWiA z W-MCO | Olsztyn | Poland | Details | |||
| Maria Skodowska Curie Memorial Cancer Centre and Institute of Oncology | Warszawa | Poland | Details | |||
| Dolnoslaskie Centrum Onkologii we Wrocawiu | Wrocław | Poland | Details | |||
| National Cancer Centre Singapore | Singapore | Singapore | Details | |||
| Hospital de la Santa Creu i Sant Pau | Barcelona | Spain | Details | |||
| Institut Català d'Oncologia - Hospital Duran i Reynals | Barcelona | Spain | Details | |||
| Vall d'Hebron | Barcelona | Spain | Details | |||
| Hospital La Paz | Madrid | Spain | Details | |||
| Hospital Universitario Gregorio Marañón | Madrid | Spain | Details | |||
| Hospital Universitario Puerta de Hierro | Madrid | Spain | Details | |||
| Hospital Virgen del Rocio | Sevilla | Spain | Details | |||
| Fundacion Instituto Valenciano de Oncologia, Servicio de Oncologia | Valencia | Spain | Details | |||
| Hospital Universitario Miguel Servet | Zaragoza | Spain | Details | |||
| Skanes University Hospital | Lund | Sweden | Details | |||
| Beatson West of Scotland Cancer Centre | Glasgow | United Kingdom | Details | |||
| The Royal Marsden Hospital | London | SW3 6JJ | United Kingdom | Details | ||
| Guy's Hospital | London | United Kingdom | Details | |||
| The Christie NHS Foundation Trust | Manchester | United Kingdom | Details | |||
| Sheffield Teaching Hospitals NHS Foundation Trust | Sheffield | United Kingdom | Details |