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| NCT ID | NCT03652064 |
| Title | A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Janssen Research & Development, LLC |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | POL | NLD | ISR | GBR | FRA | ESP | DEU | CZE | CAN | BRA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Innovative Clinical Research Inc | Cerritos | California | 90703 | United States | Details | |
| Baptist MD Anderson | Jacksonville | Florida | 32207 | United States | Details | |
| Fort Wayne Medical Oncology and Hematology, Inc. | Fort Wayne | Indiana | 46804 | United States | Details | |
| Norton Healthcare | Louisville | Kentucky | 40207 | United States | Details | |
| Tufts Medical Center | Boston | Massachusetts | 02111 | United States | Details | |
| Boston University Medical Center | Boston | Massachusetts | 02118 | United States | Details | |
| Cancer And Hematology Centers of Western Michigan PC | Grand Rapids | Michigan | 49503 | United States | Details | |
| Saint Lukes Hospital Saint Lukes Cancer Specialists | Kansas City | Missouri | 64111 | United States | Details | |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08901 | United States | Details | |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | United States | Details | |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | United States | Details | |
| NYU Winthrop | Mineola | New York | 11501 | United States | Details | |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195 | United States | Details | |
| Good Samaritan Hospital Corvallis | Corvallis | Oregon | 97330 | United States | Details | |
| University Of Pittsburgh Medical Center UPMC Hillman Cancer Center | Pittsburgh | Pennsylvania | 15232 1301 | United States | Details | |
| Gibbs Cancer Center | Spartanburg | South Carolina | 29303 | United States | Details | |
| University of Texas, MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Virginia | Charlottesville | Virginia | 22908 | United States | Details | |
| Universidade Estadual De Campinas | Campinas | 13083-878 | Brazil | Details | ||
| Liga Norte Riograndense Contra O Cancer | Natal | 59062 000 | Brazil | Details | ||
| Uniao Brasileira de Educacao e Assistencia Hospital Sao Lucas da PUCRS | Porto Alegre | 90610-000 | Brazil | Details | ||
| Ministerio da Saude Instituto Nacional do Cancer | Rio de Janeiro | 20230-130 | Brazil | Details | ||
| Instituto de Educacao, Pesquisa e Gestao em Saude Instituto Americas (COI) | Rio de Janeiro | 22775 001 | Brazil | Details | ||
| Instituto de Ensino e Pesquisa São Lucas | Sao Paulo | 01236-030 | Brazil | Details | ||
| Real e Benemerita Associacao Portuguesa de Beneficencia | Sao Paulo | 01323 900 | Brazil | Details | ||
| Instituto Brasileiro de Controle do Cancer - Sao Camilo Oncologia | Sao Paulo | 03102-002 | Brazil | Details | ||
| Clinica Medica Sao Germano S/S LTDA | Sao Paulo | 04537-081 | Brazil | Details | ||
| Hospital Santa Cruz | São Paulo | 04122-000 | Brazil | Details | ||
| Arthur J. E. Child Comprehensive Cancer Centre | Calgary | Alberta | T2N 5G2 | Canada | Details | |
| Cross Cancer Institute | Edmonton | Alberta | T6G 1Z2 | Canada | Details | |
| The Gordon & Leslie Diamond Health Care Center | Vancouver | British Columbia | V5Z 1M9 | Canada | Details | |
| QEII Health Sciences Centre | Halifax | Nova Scotia | B3H 1V7 | Canada | Details | |
| Brampton Civic Hospital | Brampton | Ontario | L6R 3J7 | Canada | Details | |
| Victoria Hospital | London | Ontario | N6A 5W9 | Canada | Details | |
| Lakeridge Health Oshawa | Oshawa | Ontario | L1G-2B9 | Canada | Details | |
| McGill University Health Centre | Montreal | Quebec | H4A 3J1 | Canada | Details | |
| CHU de Quebec L Hotel Dieu de Quebec | Quebec | G1J 1Z4 | Canada | Details | ||
| Fakultni nemocnice Brno | Brno | 625 00 | Czechia | Details | ||
| Fakultni nemocnice Hradec Kralove | Hradec Kralove | 500 05 | Czechia | Details | ||
| Fakultni Nemocnice Ostrava | Ostrava | 708 52 | Czechia | Details | ||
| Fakultni nemocnice Plzen, Hemato-onkologicke oddeleni | Plzen | 323 00 | Czechia | Details | ||
| Vseobecna fakultni nemocnice v Praze | Praha 2 | 128 08 | Czechia | Details | ||
| CHU Henri Mondor | Creteil N/a | 94010 | France | Details | ||
| Centre Hospitalier Départmental La Roche sur Yon | La Roche sur Yon Cedex 9 | 85925 | France | Details | ||
| Hopital Claude Huriez | Lille | 59037 | France | Details | ||
| Institut Paoli Calmettes | Marseille Cedex 9 | 13009 | France | Details | ||
| CHU de Montpellier Hopital Saint Eloi | Montpellier | 34295 | France | Details | ||
| CHU de Bordeaux - Hospital Haut-Leveque | Pessac cedex | 33604 | France | Details | ||
| Strasbourg Oncologie Libérale | Strasbourg | 67000 | France | Details | ||
| Institut Universitaire du cancer de Toulouse-Oncopole | Toulouse cedex 9 | 31059 | France | Details | ||
| phase 3 - Hämatoonkologischer Studienkreis am Klinikum Aschaffenburg | Aschaffenburg | 63739 | Germany | Details | ||
| Universitatsklinikum Freiburg | Freiburg | 79106 | Germany | Details | ||
| St. Josef-Krankenhaus Hamm-Bockum-Hövel | Hamm | 59075 | Germany | Details | ||
| Institut für Versorgungsforschung | Koblenz | 56068 | Germany | Details | ||
| Universitatsmedizin Leipzig | Leipzig | 4103 | Germany | Details | ||
| Klinikum Großhadern der Ludwig-Maximilians-Universität | München | 81377 | Germany | Details | ||
| Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II, | Tuebingen | 72076 | Germany | Details | ||
| Barzilai Medical Center | Ashkelon | 78741 | Israel | Details | ||
| Hillel Yaffe Medical Center | Hadera | 38100 | Israel | Details | ||
| Rambam Med.Center - Hematology Institute | Haifa | 3109601 | Israel | Details | ||
| Carmel Medical Center | Haifa | 3436212 | Israel | Details | ||
| Meir Hospital | Kfar Saba | 44281 | Israel | Details | ||
| Rabin Medical Center | Petah-Tiqva | 49100 | Israel | Details | ||
| Sheba Medical Center | Ramat Gan | 52621 | Israel | Details | ||
| Sourasky (Ichilov) Medical Center | Tel Aviv | 64239 | Israel | Details | ||
| Fukuoka University Hospital | Fukuoka | 814-0180 | Japan | Details | ||
| Ogaki Municipal Hospital | Gifu | 503-8502 | Japan | Details | ||
| Kanazawa University Hospital | Kanazawa | 920-8641 | Japan | Details | ||
| Kobe City Medical Center General Hospital | Kobe City | 650 0047 | Japan | Details | ||
| National Hospital Organization Kumamoto Medical Center | Kumamoto-shi | 860-0008 | Japan | Details | ||
| University Hospital Kyoto Prefectural University of Medicine | Kyoto | 602-8566 | Japan | Details | ||
| National Hospital Organization Matsumoto Medical Center | Matsumoto | 399-8701 | Japan | Details | ||
| Matsuyama Red Cross Hospital | Matsuyama | 790-8524 | Japan | Details | ||
| Nagoya City University Hospital | Nagoya | 467 8602 | Japan | Details | ||
| National Hospital Organization Okayama Medical Center | Okayama | 701-1192 | Japan | Details | ||
| Japanese Red Cross Osaka Hospital | Osaka | 543-8555 | Japan | Details | ||
| National Hospital Organization Shibukawa Medical Center | Shibukawa | 377-0280 | Japan | Details | ||
| Japanese Red Cross Medical Center | Shibuya | 150-8935 | Japan | Details | ||
| VU Medisch Centrum | Amsterdam | 1081 HV | Netherlands | Details | ||
| Albert Schweitzer ziekenhuis-lokatie Dordwijk | Dordrecht | 3318 AT | Netherlands | Details | ||
| Erasmus MC | Rotterdam | 3015CE | Netherlands | Details | ||
| Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza | Brzozow | 36-200 | Poland | Details | ||
| Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich | Chorzów | 41-500 | Poland | Details | ||
| Uniwersyteckie Centrum Kliniczne | Gdansk | 80-214 | Poland | Details | ||
| Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach | Kielce | 25-734 | Poland | Details | ||
| NSSU Szpital Uniwersytecki w Krakowie | Krakow | 30 688 | Poland | Details | ||
| Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli | Lublin | 20090 | Poland | Details | ||
| Uniwersytecki Szpital Kliniczny w Poznaniu | Poznan | 60-569 | Poland | Details | ||
| Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka | Slupsk | 76-200 | Poland | Details | ||
| Instytut Hematologii i Transfuzjologii | Warszawa | 02-776 | Poland | Details | ||
| Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
| Hosp. Univ. Fundacion Alcorcon | Alcorcon | 28922 | Spain | Details | ||
| Hosp. Del Mar | Barcelona | 08003 | Spain | Details | ||
| Hosp. Univ. de Guadalajara | Guadalajara | 19002 | Spain | Details | ||
| Hosp. Univ. Pta. de Hierro Majadahonda | Majadahonda | 28222 | Spain | Details | ||
| Hosp. Quiron Madrid Pozuelo | Pozuelo De Alarcon, Madrid | 28223 | Spain | Details | ||
| Hosp. Mutua Terrassa | Terrassa | 08221 | Spain | Details | ||
| Gulhane Egitim ve Arastirma Hastanesi | Ankara | 06010 | Turkey | Details | ||
| Hacettepe University Medical Faculty | Ankara | 06100 | Turkey | Details | ||
| Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital | Ankara | 06200 | Turkey | Details | ||
| Ankara University School of Medicine Cebeci Hospital | Ankara | 06590 | Turkey | Details | ||
| Istanbul University Istanbul Medical Faculty | Istanbul | 34093 | Turkey | Details | ||
| Dokuz Eylul University Medical Faculty | Izmir | 35340 | Turkey | Details | ||
| Ondokuz Mayis University | Samsun | 55280 | Turkey | Details | ||
| Monklands District General Hospital | Airdrie | ML6 0JS | United Kingdom | Details | ||
| Blackpool Victoria Hospital | Blackpool | FY3 8NR | United Kingdom | Details | ||
| University Hospital Wales | Cardiff | CF14 4XN | United Kingdom | Details | ||
| Colchester Hospital University NHS | Colchester | CO4 5JL | United Kingdom | Details | ||
| Leicester Royal Infirmary - Haematology | Leicester | LE1 5WW | United Kingdom | Details | ||
| Altnagelvin Hospital | Londonderry | BT47 6SB | United Kingdom | Details | ||
| The Royal Oldham Hospital | Oldham | OL1 2JH | United Kingdom | Details | ||
| Derriford Hospital | Plymouth | PL6 8DH | United Kingdom | Details | ||
| New Cross Hospital | Wolverhampton | WV10 0QP | United Kingdom | Details |