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| NCT ID | NCT03719690 |
| Title | Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy (AIM-HN/SEQ-HN) |
| Acronym | AIM-HN/SEQ-HN |
| Recruitment | Completed |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Kura Oncology, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NOR | NLD | ITA | GRC | GBR | ESP | DNK | DEU | BEL | AUT | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Southern California Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | United States | Details | |
| UCLA - Jonsson Comprehensive Cancer Center | Los Angeles | California | 90095 | United States | Details | |
| UCSF - Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | United States | Details | |
| The Oncology Institute of Hope and Innovation - Anaheim | Whittier | California | 90603 | United States | Details | |
| Miami Cancer Institute | Miami | Florida | 33176 | United States | Details | |
| University of South Florida H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612 | United States | Details | |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | United States | Details | |
| University of Chicago | Chicago | Illinois | 60637 | United States | Details | |
| University Of Kansas Medical Center | Westwood | Kansas | 66205 | United States | Details | |
| University of Kentucky Markey Cancer Center | Lexington | Kentucky | 40536 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| Greater Baltimore Medical Center | Baltimore | Maryland | 21204 | United States | Details | |
| Marlene and Stewart Greenebaum Cancer Center | Baltimore | Maryland | 21287 | United States | Details | |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | United States | Details | |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
| Mayo Clinic | Rochester | Minnesota | 55905 | United States | Details | |
| Siteman Cancer Center - Washington University Medical Campus | Saint Louis | Missouri | 63129 | United States | Details | |
| New York University Langone Medical Center | New York | New York | 10016 | United States | Details | |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | United States | Details | |
| The Ohio State University | Columbus | Ohio | 43210 | United States | Details | |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | United States | Details | |
| Vanderbilt University Medical Center-Vanderbilt Ingram Cancer Center | Nashville | Tennessee | 37232 | United States | Details | |
| San Antonio Military Medical Center | Fort Sam Houston | Texas | 78234 | United States | Details | |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | United States | Details | |
| University of Texas Health San Antonio - Mays Cancer Center | San Antonio | Texas | 78229 | United States | Details | |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | United States | Details | |
| University of Wisconsin | Madison | Wisconsin | 53705 | United States | Details | |
| Peter MacCallum Cancer Centre | Melbourne | 3000 | Australia | Details | ||
| Royal North Shore Hospital | Saint Leonards | 2065 | Australia | Details | ||
| Allgemeines Krankenhaus der Stadt Wien | Wien | 1090 | Austria | Details | ||
| Hanusch Krankenhaus Wiener Gebietskrankenkasse | Wien | 1140 | Austria | Details | ||
| Centre Hospitalier Universitaire Universite Catholique de Louvain Site Godinne | Yvoir | Namur | 5530 | Belgium | Details | |
| Ziekenhuis Netwerk Antwerpen Middelheim | Antwerpen | 2020 | Belgium | Details | ||
| Cliniques Universitaires Saint-Luc | Brussels | 1200 | Belgium | Details | ||
| Universitair Ziekenhuis Antwerpen | Edegem | 2650 | Belgium | Details | ||
| Universitair Ziekenhuis Leuven | Leuven | 3000 | Belgium | Details | ||
| Rigshospitalet | Copenhagen | 2100 | Denmark | Details | ||
| Herlev Hospital | Herlev | 2730 | Denmark | Details | ||
| Charité Universitätsmedizin Berlin | Berlin | 12203 | Germany | Details | ||
| Universitätsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
| Universitätsmedizin Mannheim | Mannheim | 68167 | Germany | Details | ||
| Universitätsklinikum Würzburg | Würzburg | 97080 | Germany | Details | ||
| University General Hospital of Athens Attikon | Chaidari | 12462 | Greece | Details | ||
| University General Hospital of Larissa | Larissa | 41110 | Greece | Details | ||
| Bioclinic - Thessaloniki | Thessaloniki | 54622 | Greece | Details | ||
| Azienda Ospedaliero Universitaria di Bologna Policlinico Sant'Orsola-Malpighi | Bologna | 40138 | Italy | Details | ||
| Azienda Ospedaliera S. Croce e Carle Cuneo | Cuneo | 12100 | Italy | Details | ||
| Ospedale Mater Salutis di Legnago | Legnago | 37045 | Italy | Details | ||
| Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori | Meldola | 47014 | Italy | Details | ||
| Fondazione IRCCS - Istituto Nazionale dei Tumori - Milano | Milano | 20133 | Italy | Details | ||
| Istituto Nazionale Tumori IRCCS Fondazione Pascale | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Senese-L'ospedale Santa Maria alle Scotte | Siena | 53100 | Italy | Details | ||
| National Cancer Center | Goyang-si | 10408 | Korea, Republic of | Details | ||
| Chonbuk National University Hospital | Jeonju | 54907 | Korea, Republic of | Details | ||
| Korea University Anam Hospital | Seoul | 02841 | Korea, Republic of | Details | ||
| Yonsei University Health System Severance Hospital | Seoul | 03722 | Korea, Republic of | Details | ||
| Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
| Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
| The Catholic University of Korea - Seoul St. Mary's Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
| The Catholic University of Korea St. Vincent's Hospital | Suwon | 16247 | Korea, Republic of | Details | ||
| University Malaya Medical Centre | Kuala Lumpur | 59100 | Malaysia | Details | ||
| Institut Kanser Negara | Putrajaya | 62250 | Malaysia | Details | ||
| Universitair Medisch Centrum Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
| Maastricht University Medical Centre | Maastricht | 6229 HX | Netherlands | Details | ||
| Universitair Medisch Centrum Utrecht | Utrecht | 3584 CX | Netherlands | Details | ||
| Haukeland Universitetssjukehus | Bergen | 1521 | Norway | Details | ||
| Radiumhospitalet | Oslo | 0379 | Norway | Details | ||
| Hospital del Mar - Parc de Salut Mar | Barcelona | 08003 | Spain | Details | ||
| Hospital de la Santa Creu i de Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Hospital Universitari Vall d'Hebrón | Barcelona | 08035 | Spain | Details | ||
| Hospital Clinic i Provincial de Barcelona | Barcelona | 08036 | Spain | Details | ||
| Hospital Duran i Reynals | Barcelona | 08908 | Spain | Details | ||
| Hospital Universitario 12 de Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| HM Centro Integral Oncológico Clara Campal | Madrid | 28050 | Spain | Details | ||
| Hospital Costa Del Sol | Marbella | 29603 | Spain | Details | ||
| Hospital Universitario Virgen de la Victoria | Málaga | 29010 | Spain | Details | ||
| Complejo Hospitalario de Navarra | Pamplona | 31008 | Spain | Details | ||
| Hospital Clínico Universitario de Santiago de Compostela | Santiago De Compostela | 15707 | Spain | Details | ||
| Hospital Universitario Virgen del Rocio | Sevilla | 41013 | Spain | Details | ||
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | 46026 | Spain | Details | ||
| Hospital Universitario Miguel Servet | Zaragoza | 50009 | Spain | Details | ||
| Changhua Christian Hospital | Changhua | 500 | Taiwan | Details | ||
| Kaohsiung Chang Gung Memorial Hospital | Kaohsiung | 83301 | Taiwan | Details | ||
| Chang Gung Medical Foundation Keelung Chang Gung Memorial Hospital | Keelung | 20442 | Taiwan | Details | ||
| China Medical University Hospital | Taichung | 40447 | Taiwan | Details | ||
| Taichung Veterans General Hospital | Taichung | 407 | Taiwan | Details | ||
| National Cheng Kung University Hospital | Tainan | 70403 | Taiwan | Details | ||
| Mackay Memorial Hospital | Taipei | 10099 | Taiwan | Details | ||
| National Taiwan University Hospital | Taipei | 100 | Taiwan | Details | ||
| Chang Gung Memorial Hospital | Taoyuan | 33305 | Taiwan | Details | ||
| King Chulalongkorn Memorial Hospital | Bangkok | 10330 | Thailand | Details | ||
| Maharaj Nakorn Chiang Mai Hospital | Chiang Mai | 50200 | Thailand | Details | ||
| Songklanagarind Hospital | Hat Yai | 90110 | Thailand | Details | ||
| Guy's and Saint Thomas' NHS Foundation Trust | London | England | SE1 9RT | United Kingdom | Details | |
| NHS Greater Glasgow and Clyde | Glasgow | G12 0XH | United Kingdom | Details | ||
| University College London Hospitals NHS Foundation Trust | London | NW1 2BU | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust | London | SW3 6JJ | United Kingdom | Details | ||
| The Christie NHS Foundation Trust | Manchester | M20 4BX | United Kingdom | Details | ||
| The Royal Marsden NHS Foundation Trust | Sutton | SM2 5PT | United Kingdom | Details |