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| NCT ID | NCT03742895 |
| Title | Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | ROU | ITA | ISR | IRL | GBR | FRA | ESP | DNK | CHE | CAN | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The University of Arizona Cancer Center - North Campus ( Site 0011) | COMPLETED | Tucson | Arizona | 85719 | United States | Details |
| St Joseph Heritage Healthcare-Oncology ( Site 0056) | COMPLETED | Fullerton | California | 92835 | United States | Details |
| Cedars Sinai Medical Center ( Site 0002) | COMPLETED | Los Angeles | California | 90048 | United States | Details |
| UCSF Helen Diller Family Comprehensive Cancer Center ( Site 0007) | COMPLETED | San Francisco | California | 94158 | United States | Details |
| Rocky Mountain Regional Veterans Affairs Medical Center ( Site 0092) | COMPLETED | Aurora | Colorado | 80045 | United States | Details |
| Winship Cancer Institute of Emory University ( Site 0025) | COMPLETED | Atlanta | Georgia | 30322-1013 | United States | Details |
| Augusta University ( Site 0028) | COMPLETED | Augusta | Georgia | 30912 | United States | Details |
| Markey Cancer Center ( Site 0018) | COMPLETED | Lexington | Kentucky | 40536 | United States | Details |
| University of Maryland ( Site 0050) | COMPLETED | Baltimore | Maryland | 21201 | United States | Details |
| Weinberg Cancer Institute at Franklin Square ( Site 0054) | COMPLETED | Baltimore | Maryland | 21237 | United States | Details |
| University of Massachusetts ( Site 0017) | COMPLETED | Worcester | Massachusetts | 01655 | United States | Details |
| Henry Ford Health System ( Site 0060) | COMPLETED | Detroit | Michigan | 48202 | United States | Details |
| Cancer Partners of Nebraska ( Site 0051) | COMPLETED | Lincoln | Nebraska | 68510 | United States | Details |
| Memorial Sloan Kettering Cancer Center- Monmouth ( Site 0116) | RECRUITING | Middletown | New Jersey | 07748 | United States | Details |
| Memorial Sloan-Kettering Cancer Center at West Harrison ( Site 0126) | RECRUITING | Harrison | New York | 10604 | United States | Details |
| VA New York Harbor Healthcare System Manhattan ( Site 0094) | COMPLETED | New York | New York | 10010 | United States | Details |
| Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0057) | COMPLETED | New York | New York | 10016 | United States | Details |
| Memorial Sloan Kettering Cancer Center ( Site 0026) | RECRUITING | New York | New York | 10065 | United States | Details |
| Southwestern Regional Medical Center, Inc. ( Site 0079) | COMPLETED | Tulsa | Oklahoma | 74133 | United States | Details |
| Eastern Regional Medical Center, Inc. ( Site 0077) | COMPLETED | Philadelphia | Pennsylvania | 19124 | United States | Details |
| Sanford Hematology Oncology-Sioux Falls SD ( Site 0012) | COMPLETED | Sioux Falls | South Dakota | 57104 | United States | Details |
| Intermountain Healthcare ( Site 0043) | COMPLETED | Saint George | Utah | 84790 | United States | Details |
| Virginia Mason Medical Center ( Site 0052) | COMPLETED | Seattle | Washington | 98101 | United States | Details |
| Veterans Affairs Puget Sound Health Care System [Seattle, WA] ( Site 0093) | COMPLETED | Seattle | Washington | 98108 | United States | Details |
| Centro de Oncologia e Investigacion Buenos Aires COIBA ( Site 2703) | COMPLETED | Berazategui | Buenos Aires | B1884BBF | Argentina | Details |
| Hospital Britanico de Buenos Aires ( Site 2704) | COMPLETED | Ciudad de Buenos Aires | Caba | C1280AEB | Argentina | Details |
| Instituto de Investigaciones Metabolicas ( Site 2700) | COMPLETED | Buenos Aires | C1012AAR | Argentina | Details | |
| Hospital Aleman ( Site 2702) | ACTIVE_NOT_RECRUITING | Buenos Aires | C1118AAT | Argentina | Details | |
| Kinghorn Cancer Centre ( Site 2200) | RECRUITING | Darlinghurst | New South Wales | 2010 | Australia | Details |
| MNCCI Port Macquarie Base Hospital ( Site 2201) | COMPLETED | Port Macquarie | New South Wales | 2444 | Australia | Details |
| Linear Clinical Research Ltd ( Site 2202) | COMPLETED | Nedlands | Western Australia | 6009 | Australia | Details |
| Sunnybrook Research Institute ( Site 0210) | COMPLETED | Toronto | Ontario | M4N 3M5 | Canada | Details |
| Hopital Maisonneuve-Rosemont CIUSSS de l Est de L Ile de Montreal ( Site 0203) | RECRUITING | Montreal | Quebec | H1T 2M4 | Canada | Details |
| Jewish General Hospital ( Site 0209) | COMPLETED | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0 | COMPLETED | Quebec | G1J 1Z4 | Canada | Details | |
| Fundacion Centro de Investigacion Clinica CIC ( Site 2812) | COMPLETED | Medellin | Antioquia | 050021 | Colombia | Details |
| Rodrigo Botero SAS ( Site 2801) | COMPLETED | Medellin | Antioquia | 050030 | Colombia | Details |
| Biomelab S A S ( Site 2800) | COMPLETED | Barranquilla | Atlantico | 080001 | Colombia | Details |
| Sociedad de Oncología Y Hematología del Cesar S.A.S. ( Site 2808) | COMPLETED | Valledupar | Cesar | 200001 | Colombia | Details |
| Oncomedica S.A. ( Site 2806) | COMPLETED | Monteria | Cordoba | 230002 | Colombia | Details |
| Administradora Country SA - Clinica del Country ( Site 2802) | COMPLETED | Bogota | Distrito Capital De Bogota | 110221 | Colombia | Details |
| Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 2807) | COMPLETED | Bogota | Distrito Capital De Bogota | 110311 | Colombia | Details |
| Instituto Nacional de Cancerologia E.S.E ( Site 2809) | COMPLETED | Bogota | Distrito Capital De Bogota | 111511 | Colombia | Details |
| C. Medico Imbanaco Cali S.A. ( Site 2810) | COMPLETED | Cali | Valle Del Cauca | 760042 | Colombia | Details |
| Rigshospitalet ( Site 0402) | COMPLETED | Copenhagen | Hovedstaden | 2100 | Denmark | Details |
| Herlev og Gentofte Hospital. ( Site 0401) | RECRUITING | Herlev | Hovedstaden | 2730 | Denmark | Details |
| Odense Universitetshospital ( Site 0400) | COMPLETED | Odense | Syddanmark | 5000 | Denmark | Details |
| CHU Poitiers ( Site 0612) | COMPLETED | Poitiers | Ain | 86021 | France | Details |
| Centre Antoine Lacassagne ( Site 0610) | COMPLETED | Nice | Alpes-Maritimes | 06189 | France | Details |
| Institut de Cancerologie Strasbourg Europe ( Site 0613) | COMPLETED | Strasbourg | Alsace | 67033 | France | Details |
| Centre Georges Francois Leclerc ( Site 0608) | COMPLETED | Dijon | Bourgogne | 21000 | France | Details |
| Institut Bergonie ( Site 0603) | COMPLETED | Bordeaux | Gironde | 33076 | France | Details |
| Institut Gustave Roussy ( Site 0601) | ACTIVE_NOT_RECRUITING | Villejuif | Val-de-Marne | 94805 | France | Details |
| Centro Regional de Sub Especialidades Medicas SA ( Site 3003) | RECRUITING | Guatemala | Quetzaltenango | 09001 | Guatemala | Details |
| Centro de Investigaciones Clinicas de Latinoamerica S.A. - CELAN ( Site 3004) | RECRUITING | Guatemala | 01010 | Guatemala | Details | |
| Integra Cancer Institute ( Site 3006) | RECRUITING | Guatemala | 01010 | Guatemala | Details | |
| Grupo Angeles SA ( Site 3001) | RECRUITING | Guatemala | 01015 | Guatemala | Details | |
| Mater Misericordiae University Hospital ( Site 1654) | COMPLETED | Dublin | Carlow | D07 WKW8 | Ireland | Details |
| Bon Secours Hospital ( Site 1656) | COMPLETED | Cork | T12 DV56 | Ireland | Details | |
| St. Vincent's University Hospital ( Site 1653) | RECRUITING | Dublin | 00004 | Ireland | Details | |
| Tallaght University Hospital ( Site 1652) | COMPLETED | Dublin | D24 NROA | Ireland | Details | |
| Soroka Medical Center ( Site 0800) | COMPLETED | Beer-Sheva | 8457108 | Israel | Details | |
| Rambam Health Care Campus-Oncology Division ( Site 0801) | COMPLETED | Haifa | 3109601 | Israel | Details | |
| Hadassah Ein Kerem Medical Center ( Site 0802) | COMPLETED | Jerusalem | 9112001 | Israel | Details | |
| Chaim Sheba Medical Center ( Site 0803) | ACTIVE_NOT_RECRUITING | Ramat Gan | 5262000 | Israel | Details | |
| Sourasky Medical Center ( Site 0804) | COMPLETED | Tel Aviv | 6423906 | Israel | Details | |
| Istituto Nazionale Tumori Fondazione Pascale ( Site 0700) | COMPLETED | Napoli | Campania | 80131 | Italy | Details |
| Istituto Clinico Humanitas Research Hospital ( Site 0703) | COMPLETED | Rozzano | Lombardia | 20089 | Italy | Details |
| Policlinico Le Scotte di Siena ( Site 0704) | COMPLETED | Siena | Toscana | 53100 | Italy | Details |
| Aichi Cancer Center Hospital ( Site 2602) | ACTIVE_NOT_RECRUITING | Nagoya | Aichi | 464-8681 | Japan | Details |
| National Cancer Center Hospital East ( Site 2600) | ACTIVE_NOT_RECRUITING | Kashiwa | Chiba | 2778577 | Japan | Details |
| Kyoto University Hospital ( Site 2603) | COMPLETED | Kyoto-shi | Kyoto | 606-8507 | Japan | Details |
| Osaka University Hospital ( Site 2604) | COMPLETED | Suita | Osaka | 565-0871 | Japan | Details |
| National Cancer Center Hospital ( Site 2601) | ACTIVE_NOT_RECRUITING | Tokyo | 104-0045 | Japan | Details | |
| The Cancer Institute Hospital of JFCR ( Site 2605) | COMPLETED | Tokyo | 135-8550 | Japan | Details | |
| Seoul National University Bundang Hospital ( Site 2402) | RECRUITING | Seongnam-si | Kyonggi-do | 13620 | Korea, Republic of | Details |
| Seoul National University Hospital ( Site 2401) | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Severance Hospital Yonsei University Health System ( Site 2400) | COMPLETED | Seoul | 03722 | Korea, Republic of | Details | |
| Actualidad Basada en la Investigacion del Cancer ( Site 2903) | COMPLETED | Guadalajara | Jalisco | 44680 | Mexico | Details |
| Unidad Biomedica Avanzada Monterrey S. A. ( Site 2902) | COMPLETED | Monterrey | Nuevo Leon | 64460 | Mexico | Details |
| Cuidados Oncologicos ( Site 2908) | COMPLETED | Santiago De Quetaro | Queretaro | 76000 | Mexico | Details |
| Centro de Estudios de Investigacion Metabolicos y Cardiovasculares ( Site 2901) | COMPLETED | Madero | Tamaulipas | 89440 | Mexico | Details |
| Centro Estatal de Cancerologia de Chihuahua ( Site 2907) | COMPLETED | Chihuahua | 31000 | Mexico | Details | |
| CRYPTEX Investigacion Clinica S.A. de C.V. ( Site 2900) | RECRUITING | Mexico City | 06100 | Mexico | Details | |
| CENEIT Oncologicos ( Site 2904) | RECRUITING | Mexico | 03100 | Mexico | Details | |
| Oaxaca Site Management Organization S.C. ( Site 2905) | COMPLETED | Oaxaca | 68000 | Mexico | Details | |
| Hospital de Alta Complejidad de La Libertad Virgen de La Puerta ( Site 3102) | RECRUITING | Trujillo | La Libertad | 13006 | Peru | Details |
| Instituto Nacional de Enfermedades Neoplasicas ( Site 3106) | COMPLETED | Lima | Muni Metro De Lima | 15038 | Peru | Details |
| Hospital Nacional Guillermo Almenara Irigoyen ( Site 3107) | COMPLETED | Lima | 15033 | Peru | Details | |
| Clinica Internacional Sede San Borja ( Site 3100) | RECRUITING | Lima | 15036 | Peru | Details | |
| Instituto de Oncologia y Radioterapia Clinica Ricardo Palma ( Site 3101) | RECRUITING | Lima | 15036 | Peru | Details | |
| Oncosalud-Clinical Research ( Site 3108) | COMPLETED | Lima | 15036 | Peru | Details | |
| Hospital Central de la Fuerza Aerea del Peru ( Site 3104) | COMPLETED | Lima | 15046 | Peru | Details | |
| Hospital Militar Central Coronel Luis Arias Schereiber ( Site 3105) | RECRUITING | Lima | 15076 | Peru | Details | |
| Hospital Arzobispo Loayza ( Site 3103) | COMPLETED | Lima | 15082 | Peru | Details | |
| S.C. Pelican Impex S.R.L Spitalul Clinic Pelican Oradea ( Site 1102) | COMPLETED | Oradea | Bihor | 410469 | Romania | Details |
| Medisprof ( Site 1107) | COMPLETED | Cluj Napoca | Cluj | 400641 | Romania | Details |
| SC Radiotherapy Center Cluj SRL ( Site 1105) | COMPLETED | Comuna Floresti | Cluj | 407280 | Romania | Details |
| S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1103) | COMPLETED | Craiova | Dolj | 200542 | Romania | Details |
| Spitalul PDR Medlife ( Site 1106) | COMPLETED | Brasov | 500152 | Romania | Details | |
| S.C.Focus Lab Plus S.R.L ( Site 1101) | COMPLETED | Bucuresti | 022548 | Romania | Details | |
| S.C.Gral Medical S.R.L ( Site 1104) | COMPLETED | Bucuresti | 031422 | Romania | Details | |
| Arkhangelsk Clinical Oncological Dispensary ( Site 1204) | COMPLETED | Arkhangelsk | Arkhangel Skaya Oblast | 163045 | Russian Federation | Details |
| Chelyabinsk Regional Clinical Oncological Dispensary ( Site 1212) | SUSPENDED | Chelyabinsk | Chelyabinskaya Oblast | 454087 | Russian Federation | Details |
| MEDSI Clinical Hospital on Pyatnitsky Highway-Departmentof Antitumor Drug therapy ( Site 1216) | COMPLETED | Krasnogorsk | Moskovskaya Oblast | 143442 | Russian Federation | Details |
| N.N. Blokhin NMRCO ( Site 1201) | COMPLETED | Moscow | Moskva | 115477 | Russian Federation | Details |
| MSROI named after P.A. Hertsen branch of FSBI NMRC Radiology ( Site 1213) | SUSPENDED | Moscow | Moskva | 125284 | Russian Federation | Details |
| Ryazan Regional Clinical Oncology dispensary ( Site 1202) | COMPLETED | Ryazan | Ryazanskaya Oblast | 390011 | Russian Federation | Details |
| SBHI Samara Regional Clinical Oncology Dispensary ( Site 1211) | COMPLETED | Samara | Samarskaya Oblast | 443031 | Russian Federation | Details |
| Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 1208) | COMPLETED | Saint Petersburg | Sankt-Peterburg | 197758 | Russian Federation | Details |
| Clinical Hospital Saint Luka ( Site 1205) | COMPLETED | Saint-Petersburg | Sankt-Peterburg | 194044 | Russian Federation | Details |
| SBHI Leningrad Regional Clinical Hospital ( Site 1206) | COMPLETED | St.Petersburg | Sankt-Peterburg | 194291 | Russian Federation | Details |
| Republican Clinical Oncology Dispensary of Tatarstan MoH named after professor M.Z. Sigal ( Site 120 | SUSPENDED | Kazan | Tatarstan, Respublika | 420029 | Russian Federation | Details |
| Hospital Universitario Quiron Madrid ( Site 1352) | RECRUITING | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details |
| Hospital Universitari Vall d Hebron ( Site 1350) | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Universitaetsspital Zuerich ( Site 1400) | COMPLETED | Zuerich | Aargau | 8091 | Switzerland | Details |
| Hopitaux Universitaires de Geneve HUG. ( Site 1406) | COMPLETED | Geneva | Geneve | 1211 | Switzerland | Details |
| Ospedale Regionale di Bellinzona e Valli ( Site 1407) | ACTIVE_NOT_RECRUITING | Bellinzona | Ticino | 6500 | Switzerland | Details |
| Necmettin Erbakan Universitesi Meram Tip Fakultesi ( Site 1507) | RECRUITING | Konya | Adana | 42080 | Turkey | Details |
| Baskent University Adana Training Hospital ( Site 1508) | RECRUITING | Adana | 01250 | Turkey | Details | |
| Hacettepe Universitesi Tıp Fakultesi ( Site 1503) | COMPLETED | Ankara | 06100 | Turkey | Details | |
| Akdeniz Universitesi Tip Fakultesi ( Site 1504) | RECRUITING | Antalya | 07070 | Turkey | Details | |
| Trakya Universitesi Tip Fakultesi ( Site 1500) | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 1505) | RECRUITING | Istanbul | 34098 | Turkey | Details | |
| Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 1506) | RECRUITING | Istanbul | 34722 | Turkey | Details | |
| Ege Universitesi Tip Fakultesi ( Site 1502) | RECRUITING | Izmir | 35100 | Turkey | Details | |
| Churchill Hospital ( Site 1606) | COMPLETED | Oxford | Worcestershire | OX3 7LE | United Kingdom | Details |
| Christie NHS Foundation Trust ( Site 1601) | COMPLETED | Manchester | M20 4BX | United Kingdom | Details | |
| Northern Centre for Cancer Care ( Site 1602) | ACTIVE_NOT_RECRUITING | Newcastle Upon Tyne | NE7 7DN | United Kingdom | Details | |
| Weston Park Hospital ( Site 1607) | COMPLETED | Sheffield | S10 2SJ | United Kingdom | Details |