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| NCT ID | NCT03850574 |
| Title | Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia (APTIVATE) |
| Acronym | APTIVATE |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Aptose Biosciences Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NZL | ESP | DEU | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The Kirklin Clinic of UAB Hospital | RECRUITING | Birmingham | Alabama | 35233 | United States | Details |
| City of Hope Comprehensive Cancer Center | ACTIVE_NOT_RECRUITING | Duarte | California | 91010 | United States | Details |
| University of California Irvine | RECRUITING | Irvine | California | 92697 | United States | Details |
| UCSD Moores Cancer Center | RECRUITING | La Jolla | California | 92093 | United States | Details |
| USC/Norris Comprehensive Cancer Center | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| Stanford Cancer Center | RECRUITING | Palo Alto | California | 94304 | United States | Details |
| University of California, Davis | RECRUITING | Sacramento | California | 95817 | United States | Details |
| Yale University | RECRUITING | New Haven | Connecticut | 06520 | United States | Details |
| University of Miami - Miller School of Medicine | RECRUITING | Miami | Florida | 33136 | United States | Details |
| Emory University | ACTIVE_NOT_RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Massachusetts General Hospital | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Duke University Medical Center | RECRUITING | Durham | North Carolina | 27705 | United States | Details |
| Cleveland Clinic - Taussig Cancer Center | ACTIVE_NOT_RECRUITING | Cleveland | Ohio | 44106 | United States | Details |
| The Ohio State University Wexner Medical Center | RECRUITING | Columbus | Ohio | 43210 | United States | Details |
| MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Border Medical Oncology | ACTIVE_NOT_RECRUITING | Albury | New South Wales | 2640 | Australia | Details |
| Royal Brisbane and Women's Hospital | ACTIVE_NOT_RECRUITING | Herston | Queensland | 4006 | Australia | Details |
| Townsville University Hospital | ACTIVE_NOT_RECRUITING | Townsville | Queensland | 4812 | Australia | Details |
| St Vincent's Hospital Melbourne | ACTIVE_NOT_RECRUITING | Fitzroy | Victoria | 3065 | Australia | Details |
| Sir Charles Gairdner Hospital | ACTIVE_NOT_RECRUITING | Nedlands | Western Australia | 6009 | Australia | Details |
| Universitätsklinikum Leipzig | ACTIVE_NOT_RECRUITING | Leipzig | Saxony | 04103 | Germany | Details |
| Charité Universitätsmedizin Berlin | ACTIVE_NOT_RECRUITING | Berlin | 13353 | Germany | Details | |
| Kyungpook National University Hospital | ACTIVE_NOT_RECRUITING | Daegu | 41944 | Korea, Republic of | Details | |
| Pusan National University Hospital | ACTIVE_NOT_RECRUITING | Pusan | 49241 | Korea, Republic of | Details | |
| Seoul National University Bundang Hospital | ACTIVE_NOT_RECRUITING | Seongnam | 13620 | Korea, Republic of | Details | |
| Seoul National University Hospital | COMPLETED | Seoul | 03080 | Korea, Republic of | Details | |
| Asan Medical Center | ACTIVE_NOT_RECRUITING | Seoul | 05505 | Korea, Republic of | Details | |
| Samsung Medical Center | ACTIVE_NOT_RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Auckland City Hospital | ACTIVE_NOT_RECRUITING | Grafton | Auckland | 1023 | New Zealand | Details |
| Hospital Universitario Central de Asturias | ACTIVE_NOT_RECRUITING | Oviedo | Asturias | 33011 | Spain | Details |
| Hospital Quirón Madrid | ACTIVE_NOT_RECRUITING | Pozuelo De Alarcón | Madrid | 28223 | Spain | Details |
| Hospital Universitario Vall d'Hebron | ACTIVE_NOT_RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Clinico Universitario de Valencia | ACTIVE_NOT_RECRUITING | Valencia | 46010 | Spain | Details | |
| Hospital Universitari i Politècnic La Fe | ACTIVE_NOT_RECRUITING | Valencia | 46026 | Spain | Details |