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| NCT ID | NCT03940703 |
| Title | A Study of Tepotinib Plus Osimertinib in Osimertinib Relapsed MET Amplified NSCLC (INSIGHT 2) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | EMD Serono Research & Development Institute, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | FRA | ESP | DEU | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Yuma Regional Medical Center | Yuma | Arizona | 85364 | United States | Details | |
| Compassionate Care Research Group Inc - Edinger Medical Group, Inc. | Fountain Valley | California | 92708 | United States | Details | |
| Memorial Care | Long Beach | California | 90806 | United States | Details | |
| Ventura County Hematology Oncology Specialists | Oxnard | California | 93030 | United States | Details | |
| Innovative Clinical Research Institute | Whittier | California | 92801 | United States | Details | |
| Eastern Connecticut Hematology & Oncology Associates | Norwich | Connecticut | 06360 | United States | Details | |
| Holy Cross | Fort Lauderdale | Florida | 33308 | United States | Details | |
| Memorial Healthcare System | Hollywood | Florida | 33021 | United States | Details | |
| Cancer Specialists of North Florida | Jacksonville | Florida | 32256 | United States | Details | |
| Ocala Oncology | Ocala | Florida | 34474 | United States | Details | |
| University Cancer and Blood Center | Athens | Georgia | 30607 | United States | Details | |
| Hawaii Cancer Care | Honolulu | Hawaii | 96813 | United States | Details | |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | United States | Details | |
| Fort Wayne Medical Oncology and Hematology | Fort Wayne | Indiana | 46845 | United States | Details | |
| Community Health Network | Indianapolis | Indiana | 46250 | United States | Details | |
| Beacon Health | South Bend | Indiana | 46601 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40202 | United States | Details | |
| Pontchartrain | Hammond | Louisiana | 70433 | United States | Details | |
| Medstar Franklin Square Clinical Research Center | Baltimore | Maryland | 21237 | United States | Details | |
| The Center for Cancer & Blood Disorders - Maryland | Bethesda | Maryland | 20817 | United States | Details | |
| Frederick Health- James M Stockman Cancer Institute | Frederick | Maryland | 21702 | United States | Details | |
| Boston Medical Center - Dept. Hematology/Oncology | Boston | Massachusetts | 02118 | United States | Details | |
| Southcoast Center for Cancer Care | Fairhaven | Massachusetts | 02719 | United States | Details | |
| Sparrow Hospital Herbert - Herman Cancer Center | Lansing | Michigan | 48912 | United States | Details | |
| Central Care Cancer Center (CCCC) | Bolivar | Missouri | 65613 | United States | Details | |
| St. Louis Cancer Care, LLP | Bridgeton | Missouri | 63044 | United States | Details | |
| Mosaic Life Care | Saint Joseph | Missouri | 64507 | United States | Details | |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | United States | Details | |
| New Jersey Cancer Care and Blood Disorders | Belleville | New Jersey | 07109 | United States | Details | |
| Summit Medical Group | Florham Park | New Jersey | 07932 | United States | Details | |
| NYU Langone Clinical Cancer Center - NYU Langone Medical Center | New York | New York | 10016 | United States | Details | |
| NYU Langone Clinical Cancer Center - NYU Langone Medical Cente | New York | New York | 10016 | United States | Details | |
| Weill Cornell Medical College - Gastroenterology | New York | New York | 10021 | United States | Details | |
| Southeastern Medical Oncology Center | Goldsboro | North Carolina | 27534 | United States | Details | |
| University Hospitals Seidman | Cleveland | Ohio | 44106 | United States | Details | |
| OhioHealth | Columbus | Ohio | 43214 | United States | Details | |
| Oklahoma Cancer Specialists and Research Institute | Tulsa | Oklahoma | 74146 | United States | Details | |
| Oregon Oncology Specialists | Salem | Oregon | 97301 | United States | Details | |
| Gettysburg Cancer Center | Gettysburg | Pennsylvania | 17325 | United States | Details | |
| Sanford Health | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57108 | United States | Details | |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | United States | Details | |
| Tennessee Oncology | Nashville | Tennessee | 37201 | United States | Details | |
| Mary Crowley Cancer Research | Dallas | Texas | 75230 | United States | Details | |
| University of Texas MD Anderson Cancer Center - Unit 432 Thoracic Head and Neck Medical Oncology | Houston | Texas | 77030 | United States | Details | |
| Community Cancer Trials of Utah | Ogden | Utah | 84405 | United States | Details | |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | United States | Details | |
| Hematology Oncology Associates of Fredericksburg | Fredericksburg | Virginia | 22408 | United States | Details | |
| Northwest Medical Specialties | Tacoma | Washington | 98405 | United States | Details | |
| UZ Antwerpen - Department of Oncology | Edegem | Belgium | Details | |||
| UZ Leuven | Gasthuisberg | Belgium | Details | |||
| AZ Delta | Roeselare | Belgium | Details | |||
| Beijing Hospital | Beijing | China | Details | |||
| Peking Union Medical College Hospital | Beijing | China | Details | |||
| Peking University Cancer Hospital | Beijing | China | Details | |||
| Jilin Cancer Hospital - Oncology | Changchun | China | Details | |||
| The First Hospital of Jilin University | Changchun | China | Details | |||
| Hunan Cancer Hospital | Changsha | China | Details | |||
| West China Hospital, Sichuan University | Chengdu | China | Details | |||
| Fujian Cancer Hospital | Fuzhou | China | Details | |||
| Guangdong General Hospital | Guangzhou | China | Details | |||
| The First Affiliated Hospital, Zhejiang University | Hangzhou | China | Details | |||
| Zhejiang Cancer Hospital | Hangzhou | China | Details | |||
| Affiliated Tumor Hospital of Harbin Medical University | Harbin | China | Details | |||
| Anhui Chest Hospital | Hefei | China | Details | |||
| Linyi Tumor Hospital | Linyi | China | Details | |||
| Jiangsu Province Hospital | Nanjing | China | Details | |||
| Shanghai Cancer Hospital, Fudan University | Shanghai | China | Details | |||
| Shanghai Chest Hospital | Shanghai | China | Details | |||
| Liaoning Cancer Hospital & Institute | Shenyang | China | Details | |||
| The Affiliated Cancer Hospital of Xinjiang Medical university | Urumqi | China | Details | |||
| Hubei Cancer Hospital | Wuhan | China | Details | |||
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | Wuhan | China | Details | |||
| Centre Francois Baclesse - Service d'Oncologie Medicale | Caen Cedex 05 | France | Details | |||
| Centre Hospitalier Intercommunal de Créteil - Service de Pneumologie | Creteil Cedex | France | Details | |||
| CHU Limoges - Hôpital Dupuytren - Unite d'Oncologie Thoracique et Cutanée | Limoges | France | Details | |||
| Centre Léon Bérard | Lyon | France | Details | |||
| Hopital Albert Calmette - CHU Lille - service de pneumologie et immuno allergologie | Nord | France | Details | |||
| Hospital Cochin Service, Service de Pneumologie et Mucoviscidose | Paris cedex 14 | France | Details | |||
| Hopital Tenon - service pneumologie | Paris | France | Details | |||
| Groupe Hospitalier Sud - Hôpital Haut-Lévêque - Maison du Ha | Pessac | France | Details | |||
| CHU de Toulouse - Hôpital Larrey - Service de Pneumologie et Oncologie Pneumologique | Toulouse | France | Details | |||
| Universitaetsklinikum Carl Gustav Carus TU Dresden | Dresden | Germany | Details | |||
| Asklepios Fachkliniken Muenchen-Gauting - Abteilung internistische Onkologie | Gauting | Germany | Details | |||
| Universitaetsklinikum Giessen und Marburg GmbH Standort Giessen | Giessen | Germany | Details | |||
| Universitaetsmedizin Goettingen | Göttingen | Germany | Details | |||
| Evangelisches Krankenhaus Hamm gGmbH | Hamm | Germany | Details | |||
| Evangelisches Krankenhaus Hamm GmbH | Hamm | Germany | Details | |||
| Thoraxklinik-Heidelberg gGmbH | Heidelberg | Germany | Details | |||
| Staedtisches Krankenhaus Kiel | Kiel | Germany | Details | |||
| Universitaetsklinikum Koeln - Innere Medizin I, Onkologie, Haematologie | Koeln | Germany | Details | |||
| POIS Leipzig GbR | Leipzig | Germany | Details | |||
| Universitaetsklinikum Schleswig-Holstein - Campus Luebeck | Luebeck | Germany | Details | |||
| Pius-Hospital Oldenburg - Klinik f. Haematologie und Onkologie | Oldenburg | Germany | Details | |||
| Missionsärztliche Klinik | Wuerzburg | Germany | Details | |||
| Queen Elizabeth Hospital - Department of Medicine | Hong Kong | Hong Kong | Details | |||
| The University of Hong Kong | Hong Kong | Hong Kong | Details | |||
| The Chinese University of Hong Kong - Emergency Medicine | Shatin | Hong Kong | Details | |||
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Oncologia Medica | Lazio | Italy | Details | |||
| IEO Istituto Europeo di Oncologia | Milano | Italy | Details | |||
| Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo) - U.O Oncologia Medica | Monza | Italy | Details | |||
| Ospedale Monaldi | Napoli | Italy | Details | |||
| IOV - Istituto Oncologico Veneto IRCCS - Oncologia Medica 2 | Padova | Italy | Details | |||
| AO Ospedali Riuniti Cervello - Presidio Villa Sofia - U.O.S. di Neuroimmunologia | Palermo | Italy | Details | |||
| Azienda Ospedaliero Universitaria Pisana - U.O. Pneumologia II | Pisa | Italy | Details | |||
| Istituto Nazionale Tumori Regina Elena IRCCS - S.C. Oncologia Medica B | Roma | Italy | Details | |||
| Istituto Clinico Humanitas | Rozzano | Italy | Details | |||
| Azienda Socio Sanitaria Territoriale Sette Laghi (Presidio Ospedale di Circolo e Fondazione Macchi) - Oncologia Medica | Varese | Italy | Details | |||
| Azienda Ospedaliera Universitaria Integrata Verona (Ospedale Borgo Roma) - U.O.C. Oncologia | Verona | Italy | Details | |||
| Hamamatsu University School of Medicine, University Hospital - Dept of Respiratory Medicine | Hamamatsu-shi | Japan | Details | |||
| Saitama Cancer Center | Kitaadachi-gun | Japan | Details | |||
| Kurume University Hospital | Kurume-shi | Japan | Details | |||
| Nagoya University Hospital - Dept of Respiratory Medicine | Nagoya-shi | Japan | Details | |||
| Niigata Cancer Center Hospital - Dept of Internal Medicine | Niigata-shi | Japan | Details | |||
| Hyogo College of Medicine Hospital - Dept of Respiratory Medicine | Nishinomiya-shi | Japan | Details | |||
| Okayama University Hospital - Dept of Respiratory Medicine/Allergy | Okayama-shi | Japan | Details | |||
| Osaka City General Hospital | Osaka-shi | Japan | Details | |||
| Kindai University Hospital | Osakasayama-shi | Japan | Details | |||
| NHO Yamaguchi - Ube Medical Center | Ube-shi | Japan | Details | |||
| Kanagawa Cancer Center - Dept of Respiratory Medicine | Yokohama-shi | Japan | Details | |||
| National Cancer Center | Goyang-si | Korea, Republic of | Details | |||
| Chonnam National University Hwasun Hospital | Hwasun-gun | Korea, Republic of | Details | |||
| Seoul National University Bundang Hospital | Seongnam-si | Korea, Republic of | Details | |||
| Asan Medical Center | Seoul | Korea, Republic of | Details | |||
| Korea University Anam Hospital | Seoul | Korea, Republic of | Details | |||
| Samsung Medical Center | Seoul | Korea, Republic of | Details | |||
| Seoul National University Hospital | Seoul | Korea, Republic of | Details | |||
| The Catholic University of Korea, Seoul St. Mary's Hospital | Seoul | Korea, Republic of | Details | |||
| Ulsan University Hospital | Ulsan | Korea, Republic of | Details | |||
| Pantai Hospital Kuala Lumpur | Kuala Lumpur | Malaysia | Details | |||
| University Malaya Medical Centre | Kuala Lumpur | Malaysia | Details | |||
| Hospital Tengku Ampuan Afzan | Kuantan | Malaysia | Details | |||
| Hospital Umum Sarawak | Kuching | Malaysia | Details | |||
| Sunway Medical Centre | Petaling Jaya, Selangor | Malaysia | Details | |||
| Hospital Pulau Pinang - Clinic Respiratory | Pulau Pinang | Malaysia | Details | |||
| Beacon International Specialist Centre Sdn Bhd | Selangor | Malaysia | Details | |||
| The Netherlands Cancer Institute | Amsterdam | Netherlands | Details | |||
| Universitair Medisch Centrum Groningen - Department of Internal Medicine | Groningen | Netherlands | Details | |||
| Maastricht University Medical Center - Dept of Medical Oncology | Maastricht | Netherlands | Details | |||
| SBHI "Krasnoyarsk Regional Oncology Dispensary n.a. A.I. Kryzhanovsky" | Krasnoyarsk | Russian Federation | Details | |||
| "VitaMed" LLC | Moscow | Russian Federation | Details | |||
| LLC "Tonus" | Nizniy Novgorod | Russian Federation | Details | |||
| BHI of Omsk region "Clinical Oncology Dispensary" | Omsk | Russian Federation | Details | |||
| LLC "ClinicaUZI4D" | Pyatigorsk | Russian Federation | Details | |||
| FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov" | Saint-Petersburg | Russian Federation | Details | |||
| Pavlov First Saint Petersburg State Medical University - Research Institute of Pulmunology | St. Petersburg | Russian Federation | Details | |||
| Icon Cancer Centre | Connexion | Singapore | Details | |||
| National Cancer Centre - Medical Oncology Pharmacy | Singapore | Singapore | Details | |||
| Tan Tock Seng Hospital - CTRU/OCS, Research | Singapore | Singapore | Details | |||
| ICO Badalona - Hospital Germans Trias i Pujol - Servicio de Oncologia Medica | Badalona | Spain | Details | |||
| Hospital del Mar - Servicio de Oncologia | Barcelona | Spain | Details | |||
| Hospital Universitari Dexeus - Servicio de Oncologia Medica | Barcelona | Spain | Details | |||
| Hospital Universitari Quiron Dexeus - Servicio de Oncologia Medica | Barcelona | Spain | Details | |||
| Hospital Universitari Vall d'Hebron - Dept of Oncology | Barcelona | Spain | Details | |||
| ICO l´Hospitalet - Hospital Duran i Reynals - Servicio de Oncologia | L'Hospitalet de Llobregat | Spain | Details | |||
| Hospital Universitario Materno-Infantil de Canarias - Servicio de Oncologia | Las Palmas de Gran Canaria | Spain | Details | |||
| Hospital Universitario HM Madrid Sanchinarro - Servicio de Oncologia | Madrid | Spain | Details | |||
| Hospital Regional Universitario de Malaga | Málaga | Spain | Details | |||
| Hospital Universitari Son Espases - Servicio de Oncologia Medica | Palma | Spain | Details | |||
| Hospital Universitario Quiron Madrid - Unidad Integral de Oncologia | Pozuelo de Alarcon | Spain | Details | |||
| Hospital Universitario Virgen Macarena - Servicio de Oncologia | Sevilla | Spain | Details | |||
| Hospital Universitari i Politecnic La Fe - Servicio de Oncologia Medica | Valencia | Spain | Details | |||
| Kaohsiung Chang Gung Memorial Hospital | Kaohsiung | Taiwan | Details | |||
| China Medical University Hospital | Taichung | Taiwan | Details | |||
| Taichung Veterans General Hospital | Taichung | Taiwan | Details | |||
| Chi Mei Medical Center, Liou Ying | Tainan | Taiwan | Details | |||
| National Taiwan University Hospital | Taipei | Taiwan | Details | |||
| Taipei Veterans General Hospital | Taipei | Taiwan | Details | |||
| Tri-Service General Hospital | Taipei | Taiwan | Details | |||
| Siriraj Hospital | Bangkoknoi | Thailand | Details | |||
| Songklanagarind Hospital | Hat Yai | Thailand | Details | |||
| Maharaj Nakorn Chiang Mai Hospital | Muang | Thailand | Details | |||
| King Chulalongkorn Memorial Hospital | Pathumwan | Thailand | Details | |||
| Bach Mai Hospital | Hanoi | Vietnam | Details | |||
| K Hospital | Hanoi | Vietnam | Details | |||
| National Lungs Hospital | Hanoi | Vietnam | Details | |||
| Cho Ray Hospital | Ho Chi Minh City | Vietnam | Details | |||
| HCMC Oncology Hospital | Ho Chi Minh city | Vietnam | Details | |||
| Pham Ngoc Thach Hospital | Ho Chi Minh City | Vietnam | Details |