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| NCT ID | NCT04123366 |
| Title | Study of Olaparib (MK-7339) in Combination With Pembrolizumab (MK-3475) in the Treatment of Homologous Recombination Repair Mutation (HRRm) and/or Homologous Recombination Deficiency (HRD)-Positive Advanced Cancer (MK-7339-007/KEYLYNK-007) |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme Corp. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | TUR | SWE | ROU | POL | LVA | ITA | ISR | FRA | ESP | DEU | CAN | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The Kirklin Clinic ( Site 0086) | Birmingham | Alabama | 35233 | United States | Details | |
| Banner MD Anderson Cancer Center ( Site 0049) | Gilbert | Arizona | 85234 | United States | Details | |
| UC Davis Comprehensive Cancer Center ( Site 0039) | Sacramento | California | 95817 | United States | Details | |
| San Francisco Oncology Associates ( Site 0085) | San Francisco | California | 94115 | United States | Details | |
| University of California San Francisco ( Site 0015) | San Francisco | California | 94158 | United States | Details | |
| Banner MD Anderson Cancer Center ( Site 0092) | Greeley | Colorado | 80631 | United States | Details | |
| University of Florida ( Site 0078) | Gainesville | Florida | 32608 | United States | Details | |
| Winship Cancer Institute of Emory University ( Site 0057) | Atlanta | Georgia | 30322 | United States | Details | |
| Northeast Georgia Medical Center ( Site 0026) | Gainesville | Georgia | 30501 | United States | Details | |
| Northwest Georgia Oncology Centers PC ( Site 0047) | Marietta | Georgia | 30060 | United States | Details | |
| Norton Cancer Institute - St. Matthews ( Site 0024) | Louisville | Kentucky | 40207 | United States | Details | |
| Atlantic Health System ( Site 0046) | Summit | New Jersey | 07901 | United States | Details | |
| New York Cancer and Blood Specialists-Research Department ( Site 0080) | Port Jefferson Station | New York | 11776 | United States | Details | |
| University Hospitals Cleveland Medical Center ( Site 0016) | Cleveland | Ohio | 44106 | United States | Details | |
| The University of Oklahoma Health Sciences Center ( Site 0050) | Oklahoma City | Oklahoma | 73104 | United States | Details | |
| Parkland Health & Hospital System ( Site 0091) | Dallas | Texas | 75235 | United States | Details | |
| University of Texas, Southwestern Medical Center ( Site 0004) | Dallas | Texas | 75390 | United States | Details | |
| University of Texas-MD Anderson Cancer Center ( Site 0087) | Houston | Texas | 77030 | United States | Details | |
| Utah Cancer Specialists ( Site 0038) | West Valley City | Utah | 84119 | United States | Details | |
| Inova Schar Cancer Institute ( Site 0008) | Fairfax | Virginia | 22031 | United States | Details | |
| Northwest Medical Specialties, PLLC ( Site 0007) | Tacoma | Washington | 98405 | United States | Details | |
| Fundacion CIDEA ( Site 2704) | Ciudad de Buenos Aires | Caba | C1121ABE | Argentina | Details | |
| Hospital Britanico de Buenos Aires ( Site 2705) | Ciudad de Buenos Aires | Caba | C1280AEB | Argentina | Details | |
| Centro Medico Dra De Salvo ( Site 2702) | Buenos Aires | C1426ABP | Argentina | Details | ||
| CEMIC ( Site 2701) | Buenos Aires | C1431FWO | Argentina | Details | ||
| Centro Oncologico Riojano Integral ( Site 2703) | La Rioja | F5300COE | Argentina | Details | ||
| Blacktown Hospital ( Site 2202) | Blacktown | New South Wales | 2148 | Australia | Details | |
| Tasman Oncology Research Pty Ltd ( Site 2203) | Southport | Queensland | 4215 | Australia | Details | |
| Monash Medical Centre ( Site 2205) | Clayton | Victoria | 3168 | Australia | Details | |
| Linear Clinical Research Ltd ( Site 2206) | Nedlands | Western Australia | 6009 | Australia | Details | |
| BC Cancer-Vancouver Center ( Site 0203) | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Moncton Hospital - Horizon Health Network ( Site 0206) | Moncton | New Brunswick | E1C 6Z8 | Canada | Details | |
| Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0201) | Montreal | Quebec | H2X 1R9 | Canada | Details | |
| Fundación Colombiana de Cancerología Clínica Vida ( Site 2902) | Medellin | Antioquia | 050030 | Colombia | Details | |
| Clinica de la Costa S.A.S. ( Site 2900) | Barranquilla | Atlantico | 080020 | Colombia | Details | |
| Fundacion Cardiovascular de Colombia ( Site 2907) | Piedecuesta | Santander | 68017 | Colombia | Details | |
| Hemato Oncologos S.A. ( Site 2910) | Cali | Valle Del Cauca | 76001 | Colombia | Details | |
| Fundacion Valle del Lili ( Site 2909) | Cali | Valle Del Cauca | 760032 | Colombia | Details | |
| CHU Jean Minjoz ( Site 0606) | Besancon | Doubs | 25030 | France | Details | |
| Institut du Cancer de Montpellier ( Site 0610) | Montpellier | Herault | 34298 | France | Details | |
| Centre Henri Becquerel ( Site 0607) | Rouen | Seine-Maritime | 76038 | France | Details | |
| Institut Gustave Roussy ( Site 0602) | Villejuif | Val-de-Marne | 94800 | France | Details | |
| CHD Vendee ( Site 0604) | La Roche sur Yon | Vendee | 85925 | France | Details | |
| Universitaetsklinik der Ludwig-Maximilians-Universitaet Muenchen ( Site 0906) | Muenchen | Bayern | 81377 | Germany | Details | |
| Universitaetsklinik Koeln ( Site 0903) | Koeln | Nordrhein-Westfalen | 50937 | Germany | Details | |
| Charite-Universitaetsmedizin Berlin-Campus Benjamin Franklin ( Site 0902) | Berlin | 12203 | Germany | Details | ||
| Oncologika S.A. ( Site 3003) | Guatemala | 01010 | Guatemala | Details | ||
| Grupo Angeles SA ( Site 3004) | Guatemala | 01015 | Guatemala | Details | ||
| Sanatorio Nuestra Senora del Pilar ( Site 3006) | Guatemala | 01015 | Guatemala | Details | ||
| Medi-K Cayala ( Site 3005) | Guatemala | 01016 | Guatemala | Details | ||
| Centro Medico Integral De Cancerología (CEMIC) ( Site 3002) | Quetzaltenango | 09002 | Guatemala | Details | ||
| Rambam Health Care Campus-Oncology Division ( Site 0801) | Haifa | 3109601 | Israel | Details | ||
| Hadassah Ein Kerem Medical Center ( Site 0802) | Jerusalem | 9112001 | Israel | Details | ||
| Meir Medical Center ( Site 0804) | Kfar Saba | 4428164 | Israel | Details | ||
| Rabin Medical Center ( Site 0806) | Petah Tikva | 4941492 | Israel | Details | ||
| Chaim Sheba Medical Center ( Site 0800) | Ramat Gan | 5262000 | Israel | Details | ||
| Sourasky Medical Center ( Site 0805) | Tel Aviv | 6423906 | Israel | Details | ||
| Azienda Ospedaliero Universitaria di Modena Policlinico ( Site 0703) | Modena | Emilia-Romagna | 41124 | Italy | Details | |
| ASST Grande Ospedale Metropolitano Niguarda ( Site 0700) | Milano | 20162 | Italy | Details | ||
| Istituto Nazionale Tumori Fondazione Pascale ( Site 0705) | Napoli | 80131 | Italy | Details | ||
| Azienda Ospedaliera Universitaria Senese ( Site 0704) | Siena | 53100 | Italy | Details | ||
| Aichi Cancer Center Hospital ( Site 2504) | Nagoya | Aichi | 464-8681 | Japan | Details | |
| National Cancer Center Hospital East ( Site 2500) | Kashiwa | Chiba | 277-8577 | Japan | Details | |
| Hokkaido University Hospital ( Site 2502) | Sapporo | Hokkaido | 060-8648 | Japan | Details | |
| Kyushu University Hospital ( Site 2506) | Fukuoka | 812-8582 | Japan | Details | ||
| Okayama University Hospital ( Site 2505) | Okayama | 700-8558 | Japan | Details | ||
| National Cancer Center Hospital ( Site 2501) | Tokyo | 104-0045 | Japan | Details | ||
| Japanese Foundation for Cancer Research ( Site 2503) | Tokyo | 135-8550 | Japan | Details | ||
| Seoul National University Bundang Hospital ( Site 2403) | Seongnam-si | Kyonggi-do | 13605 | Korea, Republic of | Details | |
| Seoul National University Hospital ( Site 2402) | Seoul | 03080 | Korea, Republic of | Details | ||
| Severance Hospital Yonsei University Health System ( Site 2400) | Seoul | 03722 | Korea, Republic of | Details | ||
| Samsung Medical Center ( Site 2401) | Seoul | 06351 | Korea, Republic of | Details | ||
| Daugavpils Regional Hospital ( Site 2104) | Daugavpils | 5417 | Latvia | Details | ||
| Liepaja Regional Hospital ( Site 2101) | Liepaja | 3414 | Latvia | Details | ||
| Riga East Clinical University Hospital ( Site 2103) | Riga | 1079 | Latvia | Details | ||
| P. Stradina Clinical University Hospital ( Site 2102) | Riga | LV-1002 | Latvia | Details | ||
| Preparaciones Oncologicas ( Site 3102) | León | Guanajuato | 37178 | Mexico | Details | |
| Unidad Biomedica Avanzada Monterrey S. A. ( Site 3108) | Monterrey | Nuevo Leon | 64460 | Mexico | Details | |
| Centro Medico Zambrano Hellion ( Site 3105) | San Pedro Garza Garcia | Nuevo Leon | 66278 | Mexico | Details | |
| Hospital H+ Queretaro ( Site 3104) | Santiago de Queretaro | Queretaro | 76000 | Mexico | Details | |
| Centro de Estudios de Investigacion Metabolicos y Cardiovasculares ( Site 3101) | Madero | Tamaulipas | 89440 | Mexico | Details | |
| CRYPTEX Investigacion Clinica S.A. de C.V. ( Site 3103) | Ciudad de Mexico | 06100 | Mexico | Details | ||
| Clinica Integral Internacional de Oncologia S. de R.L. de C.V. ( Site 3107) | Puebla | 72530 | Mexico | Details | ||
| Hospital Nacional Carlos Alberto Seguin Escobedo ESSALUD ( Site 3206) | Arequipa | Ariqipa | 04001 | Peru | Details | |
| Hospital Nacional Daniel Alcides Carrion ( Site 3207) | Bellavista | Qallaw | 07021 | Peru | Details | |
| Hospital Nacional Adolfo Guevara Velasco ( Site 3205) | Cuzco | Qusqu | 08003 | Peru | Details | |
| Oncosalud ( Site 3200) | Lima | 15036 | Peru | Details | ||
| Instituto Nacional de Enfermedades Neoplasicas ( Site 3201) | Lima | 15038 | Peru | Details | ||
| Hospital Nacional Arzobispo Loayza ( Site 3208) | Lima | 15082 | Peru | Details | ||
| Clinica San Gabriel ( Site 3202) | Lima | 15088 | Peru | Details | ||
| Hospital Nacional Cayetano Heredia ( Site 3203) | Lima | 15102 | Peru | Details | ||
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( | Warszawa | Mazowieckie | 02-781 | Poland | Details | |
| Uniwersyteckie Centrum Kliniczne ( Site 1809) | Gdansk | Pomorskie | 80-214 | Poland | Details | |
| Hematology and Oncology Institute ( Site 0504) | Manati | 00674 | Puerto Rico | Details | ||
| Ad-Vance Medical Research LLC ( Site 0505) | Ponce | 00717 | Puerto Rico | Details | ||
| Pan American Center for Oncology Trials LLC ( Site 0501) | Rio Piedras | 00935 | Puerto Rico | Details | ||
| FDI Clinical Research ( Site 0500) | San Juan | 00927 | Puerto Rico | Details | ||
| Spitalul Judetean de Urgenta Alba Iulia ( Site 1107) | Alba Iulia | Alba | 510007 | Romania | Details | |
| Medisprof ( Site 1102) | Cluj Napoca | Cluj | 400641 | Romania | Details | |
| Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1101) | Cluj-Napoca | Cluj | 400015 | Romania | Details | |
| S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1103) | Craiova | Dolj | 200542 | Romania | Details | |
| Policlinica Oncomed SRL ( Site 1104) | Timisoara | Timis | 300239 | Romania | Details | |
| Universitas Annex National Hospital ( Site 1902) | Bloemfontein | Free State | 9301 | South Africa | Details | |
| Wits Clinical Research ( Site 1906) | Parktown-Johannesburg | Gauteng | 2193 | South Africa | Details | |
| Mary Potter Oncology Centre, Little Company of Mary Hospital ( Site 1900) | Pretoria | Gauteng | 0181 | South Africa | Details | |
| Vaal Triangle Oncology Centre ( Site 1905) | Vereeniging | Gauteng | 1930 | South Africa | Details | |
| The Oncology Centre ( Site 1904) | Durban | Kwazulu-Natal | 4091 | South Africa | Details | |
| Cancercare Rondebosch Oncology ( Site 1901) | Rondebosch | Western Cape | 7700 | South Africa | Details | |
| Hospital Quiron de Madrid ( Site 1301) | Pozuelo de Alarcon | Madrid | 28223 | Spain | Details | |
| Hospital Clinic i Provincial ( Site 1302) | Barcelona | 08036 | Spain | Details | ||
| Hospital General Universitario Gregorio Maranon ( Site 1300) | Madrid | 28007 | Spain | Details | ||
| Skanes Universitetssjukhus Lund. ( Site 2001) | Lund | Skane Lan | 221 85 | Sweden | Details | |
| Karolinska Universitetssjukhuset Solna ( Site 2000) | Solna | Stockholms Lan | 171 76 | Sweden | Details | |
| Akademiska Sjukhuset ( Site 2002) | Uppsala | Uppsala Lan | 751 85 | Sweden | Details | |
| Baskent University Adana Training Hospital ( Site 1509) | Adana | 01250 | Turkey | Details | ||
| Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 1502) | Ankara | 06100 | Turkey | Details | ||
| Gazi Universitesi Tip Fakultesi ( Site 1507) | Ankara | 06500 | Turkey | Details | ||
| Ankara Sehir Hastanesi ( Site 1508) | Ankara | 06800 | Turkey | Details | ||
| Akdeniz Universitesi Tıp Fakultesi ( Site 1503) | Antalya | 07070 | Turkey | Details | ||
| Trakya University Medical Faculty Balkan Oncology Hospital ( Site 1500) | Edirne | 22030 | Turkey | Details | ||
| Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 1504) | Istanbul | 34098 | Turkey | Details | ||
| Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi ( Site 1505) | Istanbul | 34722 | Turkey | Details | ||
| Ege Universitesi Tip Fakultesi Tulay Aktas Onkoloji Hastanesi ( Site 1501) | Izmir | 35040 | Turkey | Details | ||
| Necmettin Erbakan Universitesi Meram Tip Fakultesi ( Site 1510) | Konya | 42080 | Turkey | Details | ||
| Inonu Universitesi Medical Fakultesi ( Site 1506) | Malatya | 44280 | Turkey | Details | ||
| Cherkasy Regional Oncology Dispensary ( Site 1702) | Cherkasy | Cherkaska Oblast | 18009 | Ukraine | Details | |
| Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council ( Site 1700) | Dnipro | Dnipropetrovska Oblast | 49102 | Ukraine | Details | |
| Communal Non-Commercial Enterprise "Prykarpatski Clinical On-Department for daily treated patient ( | Ivano-Frankivsk | Ivano-Frankivska Oblast | 76018 | Ukraine | Details | |
| Communal non profit enterprise Regional Clinical Oncology Center ( Site 1704) | Kharkiv | Kharkivska Oblast | 61070 | Ukraine | Details | |
| Khmelnitskiy Regional Onkology Dispensary ( Site 1705) | Khmelnitskiy | Khmelnytska Oblast | 29009 | Ukraine | Details | |
| Kirovograd Regional oncology Dispensary ( Site 1716) | Kropyvnytsky | Kirovohradska Oblast | 25011 | Ukraine | Details | |
| Medical Centre Consilium Medical ( Site 1712) | Kyiv | Kyivska Oblast | 04050 | Ukraine | Details | |
| Podillya Regional Center of Oncology ( Site 1708) | Vinnytsia | Vinnytska Oblast | 21029 | Ukraine | Details | |
| Medical center of the Limited Liability Company Yulis ( Site 1714) | Zaporizhzhia | Zaporizka Oblast | 69035 | Ukraine | Details | |
| Zhytomyr Regional Oncology Center ( Site 1710) | Zhytomyr | Zhytomyrska Oblast | 10002 | Ukraine | Details |