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| NCT ID | NCT04315324 |
| Title | Study to Test AKR1C3-Activated Prodrug OBI-3424 (OBI-3424) in Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Southwest Oncology Group |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | RECRUITING | Birmingham | Alabama | 35233 | United States | Details |
| Kingman Regional Medical Center | RECRUITING | Kingman | Arizona | 86401 | United States | Details |
| PCR Oncology | RECRUITING | Arroyo Grande | California | 93420 | United States | Details |
| City of Hope Comprehensive Cancer Center | RECRUITING | Duarte | California | 91010 | United States | Details |
| Emory University Hospital/Winship Cancer Institute | RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| Loyola Center for Health at Burr Ridge | ACTIVE_NOT_RECRUITING | Burr Ridge | Illinois | 60527 | United States | Details |
| Northwestern University | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| University of Illinois | RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| University of Chicago Comprehensive Cancer Center | RECRUITING | Chicago | Illinois | 60637 | United States | Details |
| Loyola Medicine Homer Glen | ACTIVE_NOT_RECRUITING | Homer Glen | Illinois | 60491 | United States | Details |
| Northwestern Medicine Lake Forest Hospital | ACTIVE_NOT_RECRUITING | Lake Forest | Illinois | 60045 | United States | Details |
| Loyola University Medical Center | ACTIVE_NOT_RECRUITING | Maywood | Illinois | 60153 | United States | Details |
| Marjorie Weinberg Cancer Center at Loyola-Gottlieb | ACTIVE_NOT_RECRUITING | Melrose Park | Illinois | 60160 | United States | Details |
| UC Comprehensive Cancer Center at Silver Cross | RECRUITING | New Lenox | Illinois | 60451 | United States | Details |
| University of Chicago Medicine-Orland Park | RECRUITING | Orland Park | Illinois | 60462 | United States | Details |
| Mary Greeley Medical Center | RECRUITING | Ames | Iowa | 50010 | United States | Details |
| McFarland Clinic - Ames | RECRUITING | Ames | Iowa | 50010 | United States | Details |
| McFarland Clinic - Boone | RECRUITING | Boone | Iowa | 50036 | United States | Details |
| McFarland Clinic - Trinity Cancer Center | RECRUITING | Fort Dodge | Iowa | 50501 | United States | Details |
| McFarland Clinic - Jefferson | RECRUITING | Jefferson | Iowa | 50129 | United States | Details |
| McFarland Clinic - Marshalltown | RECRUITING | Marshalltown | Iowa | 50158 | United States | Details |
| Wayne State University/Karmanos Cancer Institute | ACTIVE_NOT_RECRUITING | Detroit | Michigan | 48201 | United States | Details |
| Weisberg Cancer Treatment Center | ACTIVE_NOT_RECRUITING | Farmington Hills | Michigan | 48334 | United States | Details |
| Fairview Ridges Hospital | SUSPENDED | Burnsville | Minnesota | 55337 | United States | Details |
| Minnesota Oncology - Burnsville | RECRUITING | Burnsville | Minnesota | 55337 | United States | Details |
| Cambridge Medical Center | RECRUITING | Cambridge | Minnesota | 55008 | United States | Details |
| Mercy Hospital | RECRUITING | Coon Rapids | Minnesota | 55433 | United States | Details |
| Fairview Southdale Hospital | RECRUITING | Edina | Minnesota | 55435 | United States | Details |
| Unity Hospital | ACTIVE_NOT_RECRUITING | Fridley | Minnesota | 55432 | United States | Details |
| Fairview Clinics and Surgery Center Maple Grove | RECRUITING | Maple Grove | Minnesota | 55369 | United States | Details |
| Minnesota Oncology Hematology PA-Maplewood | RECRUITING | Maplewood | Minnesota | 55109 | United States | Details |
| Saint John's Hospital - Healtheast | RECRUITING | Maplewood | Minnesota | 55109 | United States | Details |
| Abbott-Northwestern Hospital | RECRUITING | Minneapolis | Minnesota | 55407 | United States | Details |
| Hennepin County Medical Center | RECRUITING | Minneapolis | Minnesota | 55415 | United States | Details |
| Health Partners Inc | RECRUITING | Minneapolis | Minnesota | 55454 | United States | Details |
| Monticello Cancer Center | RECRUITING | Monticello | Minnesota | 55362 | United States | Details |
| New Ulm Medical Center | RECRUITING | New Ulm | Minnesota | 56073 | United States | Details |
| Fairview Northland Medical Center | RECRUITING | Princeton | Minnesota | 55371 | United States | Details |
| North Memorial Medical Health Center | RECRUITING | Robbinsdale | Minnesota | 55422 | United States | Details |
| Park Nicollet Clinic - Saint Louis Park | RECRUITING | Saint Louis Park | Minnesota | 55416 | United States | Details |
| Regions Hospital | RECRUITING | Saint Paul | Minnesota | 55101 | United States | Details |
| United Hospital | RECRUITING | Saint Paul | Minnesota | 55102 | United States | Details |
| Saint Francis Regional Medical Center | RECRUITING | Shakopee | Minnesota | 55379 | United States | Details |
| Lakeview Hospital | RECRUITING | Stillwater | Minnesota | 55082 | United States | Details |
| Ridgeview Medical Center | RECRUITING | Waconia | Minnesota | 55387 | United States | Details |
| Rice Memorial Hospital | RECRUITING | Willmar | Minnesota | 56201 | United States | Details |
| Minnesota Oncology Hematology PA-Woodbury | RECRUITING | Woodbury | Minnesota | 55125 | United States | Details |
| Fairview Lakes Medical Center | RECRUITING | Wyoming | Minnesota | 55092 | United States | Details |
| Carson Tahoe Regional Medical Center | RECRUITING | Carson City | Nevada | 89703 | United States | Details |
| Cancer and Blood Specialists-Henderson | RECRUITING | Henderson | Nevada | 89052 | United States | Details |
| Comprehensive Cancer Centers of Nevada - Henderson | RECRUITING | Henderson | Nevada | 89052 | United States | Details |
| Comprehensive Cancer Centers of Nevada-Horizon Ridge | RECRUITING | Henderson | Nevada | 89052 | United States | Details |
| Las Vegas Cancer Center-Henderson | SUSPENDED | Henderson | Nevada | 89052 | United States | Details |
| OptumCare Cancer Care at Seven Hills | RECRUITING | Henderson | Nevada | 89052 | United States | Details |
| Comprehensive Cancer Centers of Nevada-Southeast Henderson | RECRUITING | Henderson | Nevada | 89074 | United States | Details |
| GenesisCare USA - Henderson | RECRUITING | Henderson | Nevada | 89074 | United States | Details |
| Las Vegas Urology - Green Valley | RECRUITING | Henderson | Nevada | 89074 | United States | Details |
| Las Vegas Urology - Pebble | RECRUITING | Henderson | Nevada | 89074 | United States | Details |
| Urology Specialists of Nevada - Green Valley | RECRUITING | Henderson | Nevada | 89074 | United States | Details |
| Las Vegas Urology - Pecos | RECRUITING | Las Vegas | Nevada | 89074 | United States | Details |
| Desert West Surgery | SUSPENDED | Las Vegas | Nevada | 89102 | United States | Details |
| OptumCare Cancer Care at Charleston | RECRUITING | Las Vegas | Nevada | 89102 | United States | Details |
| University Medical Center of Southern Nevada | RECRUITING | Las Vegas | Nevada | 89102 | United States | Details |
| Hope Cancer Care of Nevada | RECRUITING | Las Vegas | Nevada | 89103 | United States | Details |
| Radiation Oncology Centers of Nevada Central | RECRUITING | Las Vegas | Nevada | 89106 | United States | Details |
| Urology Specialists of Nevada - Central | RECRUITING | Las Vegas | Nevada | 89106 | United States | Details |
| GenesisCare USA - Las Vegas | RECRUITING | Las Vegas | Nevada | 89109 | United States | Details |
| HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | SUSPENDED | Las Vegas | Nevada | 89109 | United States | Details |
| Sunrise Hospital and Medical Center | RECRUITING | Las Vegas | Nevada | 89109 | United States | Details |
| HealthCare Partners Medical Group Oncology/Hematology-San Martin | SUSPENDED | Las Vegas | Nevada | 89113 | United States | Details |
| Las Vegas Prostate Cancer Center | RECRUITING | Las Vegas | Nevada | 89113 | United States | Details |
| Las Vegas Urology - Sunset | RECRUITING | Las Vegas | Nevada | 89113 | United States | Details |
| Urology Specialists of Nevada - Southwest | RECRUITING | Las Vegas | Nevada | 89113 | United States | Details |
| Radiation Oncology Centers of Nevada Southeast | RECRUITING | Las Vegas | Nevada | 89119 | United States | Details |
| Ann M Wierman MD LTD | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| Comprehensive Cancer Centers of Nevada - Northwest | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| GenesisCare USA - Vegas Tenaya | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| HealthCare Partners Medical Group Oncology/Hematology-Tenaya | SUSPENDED | Las Vegas | Nevada | 89128 | United States | Details |
| Las Vegas Urology - Cathedral Rock | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| Las Vegas Urology - Smoke Ranch | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| OptumCare Cancer Care at MountainView | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| Urology Specialists of Nevada - Northwest | RECRUITING | Las Vegas | Nevada | 89128 | United States | Details |
| Alliance for Childhood Diseases/Cure 4 the Kids Foundation | RECRUITING | Las Vegas | Nevada | 89135 | United States | Details |
| Comprehensive Cancer Centers of Nevada - Town Center | RECRUITING | Las Vegas | Nevada | 89144 | United States | Details |
| Comprehensive Cancer Centers of Nevada-Summerlin | RECRUITING | Las Vegas | Nevada | 89144 | United States | Details |
| Summerlin Hospital Medical Center | RECRUITING | Las Vegas | Nevada | 89144 | United States | Details |
| Las Vegas Cancer Center-Medical Center | SUSPENDED | Las Vegas | Nevada | 89148-2405 | United States | Details |
| Comprehensive Cancer Centers of Nevada | RECRUITING | Las Vegas | Nevada | 89148 | United States | Details |
| GenesisCare USA - Fort Apache | RECRUITING | Las Vegas | Nevada | 89148 | United States | Details |
| OptumCare Cancer Care at Fort Apache | RECRUITING | Las Vegas | Nevada | 89148 | United States | Details |
| HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | SUSPENDED | Las Vegas | Nevada | 89149 | United States | Details |
| Comprehensive Cancer Centers of Nevada - Central Valley | RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| University Cancer Center | RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| Hope Cancer Care of Nevada-Pahrump | RECRUITING | Pahrump | Nevada | 89048 | United States | Details |
| Renown Regional Medical Center | RECRUITING | Reno | Nevada | 89502 | United States | Details |
| Saint Mary's Regional Medical Center | RECRUITING | Reno | Nevada | 89503 | United States | Details |
| Radiation Oncology Associates | RECRUITING | Reno | Nevada | 89509 | United States | Details |
| University of New Mexico Cancer Center | RECRUITING | Albuquerque | New Mexico | 87102 | United States | Details |
| Roswell Park Cancer Institute | ACTIVE_NOT_RECRUITING | Buffalo | New York | 14263 | United States | Details |
| University of Rochester | RECRUITING | Rochester | New York | 14642 | United States | Details |
| Duke University Medical Center | RECRUITING | Durham | North Carolina | 27710 | United States | Details |
| University of Cincinnati Cancer Center-UC Medical Center | RECRUITING | Cincinnati | Ohio | 45219 | United States | Details |
| Cleveland Clinic Foundation | RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| University of Cincinnati Cancer Center-West Chester | SUSPENDED | West Chester | Ohio | 45069 | United States | Details |
| Oregon Health and Science University | RECRUITING | Portland | Oregon | 97239 | United States | Details |
| Huntsman Cancer Institute/University of Utah | RECRUITING | Salt Lake City | Utah | 84112 | United States | Details |
| Virginia Commonwealth University/Massey Cancer Center | RECRUITING | Richmond | Virginia | 23298 | United States | Details |
| Overlake Medical Center | SUSPENDED | Bellevue | Washington | 98004 | United States | Details |
| Valley Medical Center | RECRUITING | Renton | Washington | 98055 | United States | Details |
| FHCC South Lake Union | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| Fred Hutchinson Cancer Research Center | RECRUITING | Seattle | Washington | 98109 | United States | Details |
| University of Washington Medical Center - Montlake | RECRUITING | Seattle | Washington | 98195 | United States | Details |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | RECRUITING | Yakima | Washington | 98902 | United States | Details |
| West Virginia University Healthcare | RECRUITING | Morgantown | West Virginia | 26506 | United States | Details |
| Gundersen Lutheran Medical Center | RECRUITING | La Crosse | Wisconsin | 54601 | United States | Details |
| Cancer Center of Western Wisconsin | RECRUITING | New Richmond | Wisconsin | 54017 | United States | Details |