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| NCT ID | NCT04576156 |
| Title | A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Geron Corporation |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | POL | ITA | ISR | HUN | GBR | FRA | ESP | DNK | DEU | BRA | BGR | BEL | AUT | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of California-San Diego/Moores UCSD Cancer Center | La Jolla | California | 92093-1503 | United States | Details | |
| UCLA David Geffen School of Medicine | Los Angeles | California | 90096 | United States | Details | |
| Smilow Cancer Center at YNHH | New Haven | Connecticut | 06511 | United States | Details | |
| BRCR Medical Center Inc | Plantation | Florida | 33326 | United States | Details | |
| University of South Florida | Tampa | Florida | 33612 | United States | Details | |
| Norton Cancer Institute | Louisville | Kentucky | 40207 | United States | Details | |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Gabrail Cancer Center | Canton | Ohio | 44718 | United States | Details | |
| Prairie Lakes Health Care System, Inc. | Watertown | South Dakota | 57201 | United States | Details | |
| The University of Texas MD | Houston | Texas | 77030-4000 | United States | Details | |
| Northwest Medical Specialties PLLC | Seattle | Washington | 98405 | United States | Details | |
| Hospital Aleman | Ciudad de Buenos Aires | Buenos Aires | C118AAT | Argentina | Details | |
| Sanatorio de la Mujer | Rosario | Santa Fe Province | S2000ORE | Argentina | Details | |
| Sanatorio Allende | Córdoba | X5000JHQ | Argentina | Details | ||
| Royal North Shore Hospital | St Leonards | New South Wales | 2065 | Australia | Details | |
| Royal Brisbane and Women's Hospital | Herston | Queensland | 4011 | Australia | Details | |
| Royal Hobart Hospital | Hobart | Tasmania | 7000 | Australia | Details | |
| Epworth Healthcare | Richmond | Victoria | 3121 | Australia | Details | |
| Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel | Wein | Burgenland | 1130 | Austria | Details | |
| Krankenhaus der Elisabethinen | Linz | Upper Austria | 4020 | Austria | Details | |
| Kepler Universitätsklinikum Gm | Linz | Upper Austria | 4021 | Austria | Details | |
| Klinikum Wels-Grieskirchen GmbH | Wels | Upper Austria | 4600 | Austria | Details | |
| UZ Antwerpen | Edegem | Antwerpen | 2650 | Belgium | Details | |
| Centre Hospitalier de Jolimont | Haine-Saint-Paul | Hainaut | 7100 | Belgium | Details | |
| Universitair Ziekenhuis Gent | Ghent | Oost-Vlaanderen | 9000 | Belgium | Details | |
| AZ Klina | Antwerp | 2930 | Belgium | Details | ||
| Universitair Ziekenhuis Brussel - Myeloom Centrum Brussel (MCB) | Jette | Belgium | Details | |||
| Centro de oncologia Leonardo da Vinci | Fortaleza | Ceará | 60135285 | Brazil | Details | |
| Hospital das Clínicas UFG | Goiânia | Goiás | 74605 | Brazil | Details | |
| Hospital Erasto Gaertner | Curitiba | Paraná | 81520-060 | Brazil | Details | |
| Hospital de Clinicas de Porto Alegre - UFRGS | Porto Alegre | Rio Grande do Sul | 90035-903 | Brazil | Details | |
| Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa LTDA | Porto Alegre | Rio Grande do Sul | 90470340 | Brazil | Details | |
| CEPON Centro de Pesquisas Oncologicas SC | Florianópolis | 88034-000 | Brazil | Details | ||
| Hospital Israelita Albert Einstein | São Paulo | 05651-901 | Brazil | Details | ||
| Fundacao Doutor Amaral Carvalho / Hospital Amaral Carvalho | São Paulo | 17210-120 | Brazil | Details | ||
| Hospital A.C.Camargo Cancer Center - Clinical Oncology | São Paulo | Brazil | Details | |||
| UMBAL Sveti Georgi | Plovdiv | 4002 | Bulgaria | Details | ||
| Specialized Hospital for Active Therapy of Hematological dis | Sofia | 1756 | Bulgaria | Details | ||
| Oncologos del Occidente S.A | Pereira | Risaralda Department | 660000 | Colombia | Details | |
| Hospital Pablo Tobon Uribe | Antioquia | Colombia | Details | |||
| Odense University Hospital - Hematology | Odense | DK-5000 C | Denmark | Details | ||
| Centre Hospitalier Lyon | Pierre-Bénite | Auvergne-Rhône-Alpes | 69495 | France | Details | |
| CHU Bretonneau | Tours | Indre-et-Loire | 37044 | France | Details | |
| Hopital Bicetre | Paris | Le Kremlin-Bicêtre | 94270 | France | Details | |
| CHU De Nantes - Hematologie | Nantes | Loire-Atlantique | 44000 | France | Details | |
| CHU de Nice - Hopital de l'Archet II - Pharmacie | Nice | Nice Cedex 3 | 06202 | France | Details | |
| Centre Hospitalier Du Mans - Cancérologie Médicale | Le Mans | Sarthe | 72037 | France | Details | |
| CHRU Brest - Hôpital Morvan | Brest | 29609 | France | Details | ||
| CHU - Hôpital Saint Louis - Centre D'Investigations Cliniq | Paris | 75010 | France | Details | ||
| LTD Israeli-Georgian Medical R | Tbilisi | 0112 | Georgia | Details | ||
| M.Zodelava Hematology Center L | Tbilisi | 0112 | Georgia | Details | ||
| J.S.C."K.Eristavi National Cen | Tbilisi | 0159 | Georgia | Details | ||
| Multi Profile Clinic Consilium | Tbilisi | 0179 | Georgia | Details | ||
| Ltd "Medinvest - Institute of Hematology and Trans | Tbilisi | 186 | Georgia | Details | ||
| Universitätsklinikum Mannheim - University of Heidelberg | Mannheim | Baden-Wurttemberg | 68167 | Germany | Details | |
| Universitätsklinikum Tübingen | Tübingen | Baden-Wurttemberg | 72076 | Germany | Details | |
| Universitätsklinikum Carl Gust | Dresden | Free and Hanseatic City of Hamburg | 1307 | Germany | Details | |
| Universitätsklinikum Leipzig AöR | Leipzig | Saxony | 04103 | Germany | Details | |
| Martin-Luther-Universität Halle-Wittenberg | Halle | Saxony-Anhalt | 6120 | Germany | Details | |
| Dél-pesti Centrumkórház Ország | Budapest | H-1097 | Hungary | Details | ||
| Szabolcs-Szatmár-Bereg Megyei Önkormányzat Jósa András | Nyíregyháza | 4400 | Hungary | Details | ||
| Nirmal Hospital - Hematology | Surat | Gujarat | 395002 | India | Details | |
| St. John's Medical College Hospital | Bangalore | Karnataka | 560 034 | India | Details | |
| Fortis Hospital 154/9 | Bengaluru | Karnataka | 560076 | India | Details | |
| All India Institute of Medical Sciences, Dept. of Hematology, New Delhi (All India Institute Of Medical Sciences) | New Delhi | National Capital Territory of Delhi | 110029 | India | Details | |
| Sir Ganga Ram Hospital | New Delhi | National Capital Territory of Delhi | 110060 | India | Details | |
| Fortis Memorial Research Institute | Gurgaon | New Delhi | 122002 | India | Details | |
| All India Institute of Medical Sciences | Bhubaneswar | Odisha | 751019 | India | Details | |
| Nilratan Sircar Medical College | Kolkata | West Bengal | 700014 | India | Details | |
| Deenanath Mangeshkar Hospital & Research Center | Pune | 411004 | India | Details | ||
| Sahyadri Specialty Hospital | Pune | India | Details | |||
| Kaplan Medical Center | Rehovot | Central District | 7610001 | Israel | Details | |
| Shamir Medical Center (Assaf Harofeh) | Ẕerifin | Central District | 7030000 | Israel | Details | |
| Hadassah Medical Organization | Jerusalem | Jerusalem | 9112001 | Israel | Details | |
| Assuta Ashdod University Hospi | Ashdod | Southern District | 7747629 | Israel | Details | |
| Barzilai Medical Center | Ashkelon | Southern District | 78278 | Israel | Details | |
| Soroka Medical Center - Hematology Institute | Beersheba | 84101 | Israel | Details | ||
| Bnai Zion Medical Center | Haifa | 31048 | Israel | Details | ||
| Carmel MC | Haifa | 3436212 | Israel | Details | ||
| Arcispedale S.Anna - Ematologi | Cona | Ferrara | 44124 | Italy | Details | |
| AOU San Luigi Gonzaga | Orbassano | Torino | 10043 | Italy | Details | |
| PO Civile SS.Antonio e Biagio | Alessandria | 15121 | Italy | Details | ||
| A.O.di Bologna Policl.S.Orsola | Bologna | 40138 | Italy | Details | ||
| Presidio Ospedaliero Garibaldi | Catania | 95122 | Italy | Details | ||
| AOU Careggi | Florence | 50134 | Italy | Details | ||
| Clinica Ematologica, Univ. Deg | Genova | 6- 16132 | Italy | Details | ||
| Irccs Irst | Meldola | 47014 | Italy | Details | ||
| Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | Milan | 20122 | Italy | Details | ||
| ASST Grande Ospedale Metropoli | Milan | 20162 | Italy | Details | ||
| Azienda Ospedaliera San Gerard | Monza | 20900 | Italy | Details | ||
| AOU Federico II | Naples | 80122 | Italy | Details | ||
| Ospedale Civile S.Maria delle Croci, AUSL Ravenna | Ravenna | 48121 | Italy | Details | ||
| Arcispedale S Maria Nuova, AO di Reggio Emilia | Reggio Calabria | 42123 | Italy | Details | ||
| Azienda Ospedaliera Bianchi-Me | Reggio Calabria | 89124 | Italy | Details | ||
| AUSL di Rimini Ospedale Infermi di Rimini | Rimini | 47900 | Italy | Details | ||
| ASL Roma 2 - PO "S. Eugenio" | Roma | 00144 | Italy | Details | ||
| Policlinico Universitario Agostino Gemelli | Roma | 00168 | Italy | Details | ||
| AOU Città della Salute e della Scienza di Torino | Torino | 10126 | Italy | Details | ||
| Ospedale di Circolo, PO Varese | Varese | 21100 | Italy | Details | ||
| Ospedale S.Bortolo, AULSS n.6 | Vicenza | 36100 | Italy | Details | ||
| Hospital Pulau Pinang | Pulau Pinang | Georgetown | 10990 | Malaysia | Details | |
| Hospital Sultanah Aminah Johor Bahru | Johor Bahru | Johor | 80000 | Malaysia | Details | |
| Hospital Raja Perempuan Zainab II | Kota Bharu | Kelantan | 15586 | Malaysia | Details | |
| Sarawak General Hospital | Kuching | Sarawak | 93586 | Malaysia | Details | |
| Hospital Ampang | Ampang | Selangor | 68000 | Malaysia | Details | |
| Ars Medical Sp. z o.o. | Piła | Greater Poland Voivodeship | 64-920 | Poland | Details | |
| Centrum Medyczne Pratia Poznan | Skórzewo | Greater Poland Voivodeship | 60-185 | Poland | Details | |
| Pratia Onkologia Katowice | Katowice | Silesian Voivodeship | 40-519 | Poland | Details | |
| Wojewodzki Szpital Specjalistyczny | Biała Podlaska | 21-500 | Poland | Details | ||
| Centro Clinico Fundacao Champalimaud | Lisbon | 1400-038 | Portugal | Details | ||
| MONIKI - Oncology | Moscow | Moscow Oblast | 129110 | Russia | Details | |
| MUZ City Clinical Hospital # 2 | Novosibirsk | Novosibirsk Oblast | 630091 | Russia | Details | |
| Budgetary Healthcare Institution of Omsk Region | Omsk | 644013 | Russia | Details | ||
| GOU VPO Saratov State Medical University n.a. V.I. | Saratov | 410012 | Russia | Details | ||
| National University Cancer Institute (NCIS) | Singapore | Central Singapore | 119074 | Singapore | Details | |
| Singapore General Hospital | Singapore | Central Singapore | 169608 | Singapore | Details | |
| Inje University Busan Paik Hos | Busan | Busan Gwang'yeogsi [Pusan-Kwangyokshi] | 47392 | South Korea | Details | |
| Inje University Haeundae Paik Hospital | Busan | Busan Gwang'yeogsi [Pusan-Kwangyokshi] | 48108 | South Korea | Details | |
| Seoul National University Hospital - Department of Internal | Seoul | Seoul Teugbyeolsi [Seoul-T'ukp | 03080 | South Korea | Details | |
| The Catholic University of Korea | Seongdong | 6591 | South Korea | Details | ||
| Severance Hospital, Yonsei Uni | Seoul | 3722 | South Korea | Details | ||
| Institut Català d'Oncologia-Ho | Badalona | Barcelona | 08916 | Spain | Details | |
| Hospital Universitario de Gran | Las Palmas de Gran Canaria | Canary Islands | 35019 | Spain | Details | |
| H.G.U. Alicante | Alicante | 03010 | Spain | Details | ||
| H. San Pedro de Alcántara | Cáceres | 10003 | Spain | Details | ||
| Hospital Universitario Virgen | Granada | 18014 | Spain | Details | ||
| Hospital U. 12 Octubre | Madrid | 28041 | Spain | Details | ||
| H.U. La Paz | Madrid | 28046 | Spain | Details | ||
| H.U.V. de la Victoria | Málaga | 29010 | Spain | Details | ||
| H. Quirón Zaragoza | Zaragoza | 50012 | Spain | Details | ||
| Chang Gung Medical Foundation | Chiayi City | Chiayi | 613 | Taiwan | Details | |
| China Medical University Hospital - Hematology/Onc | Taichung | 404 | Taiwan | Details | ||
| Medical Park Mersin Hastanesi | Mersin | Mersin | Turkey (Türkiye) | Details | ||
| Sakarya Research and Training Hospital - Medical Oncology | Adapazarı | 54100 | Turkey (Türkiye) | Details | ||
| Gazi University Medical Faculty | Ankara | 06560 | Turkey (Türkiye) | Details | ||
| Ankara University Medical Facu | Ankara | 6590 | Turkey (Türkiye) | Details | ||
| Istanbul üniversitesi cerrahpaşa | Istanbul | 34098 | Turkey (Türkiye) | Details | ||
| Medipol Bagcilar Mega Hospital | Istanbul | 34214 | Turkey (Türkiye) | Details | ||
| Marmara university pendik training and research hospital | Istanbul | 34899 | Turkey (Türkiye) | Details | ||
| Ege Universitesi Tip Fakultesi | Izmir | 35100 | Turkey (Türkiye) | Details | ||
| St Bartholomew's Hospital | London | EC1A 7BE | United Kingdom | Details | ||
| Guys and St Thomas' Hospital | London | SE1 9RT | United Kingdom | Details | ||
| Oxford University Hospitals | Oxford | OX3 9DS | United Kingdom | Details |