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NCT ID NCT04603807
Title A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases
Recruitment Recruiting
Gender both
Phase Phase III
Variant Requirements Yes
Sponsors Hoffmann-La Roche
Indications
Therapies
Age Groups: senior | adult
Covered Countries TUR | SWE | SVK | ROU | NLD | LBN | ITA | HRV | GRC | FRA | ESP | DEU | BRA

Facility Status City State Zip Country Details
Hospital Sao Rafael - HSR RECRUITING Salvador BA 41253-190 Brazil Details
Oncocentro Serviços Médicos e Hospitalares Ltda RECRUITING Fortaleza CE 60130-241 Brazil Details
Hospitais Integrados da Gavea S/A ACTIVE_NOT_RECRUITING Brasilia DF 70390-140 Brazil Details
Oncocentro Belo Horizonte RECRUITING Belo Horizonte MG 30360-680 Brazil Details
Oncoclinicas Rio de Janeiro S.A. COMPLETED Rio de Janeiro RJ 22250-905 Brazil Details
Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda RECRUITING Ijui RS 98700-000 Brazil Details
Hospital Mae de Deus WITHDRAWN Porto Alegre RS 90110-000 Brazil Details
Centro de Pesquisa e Ensino em Oncologia de Santa Catarina - CEPEN RECRUITING Florianopolis SC 88020-210 Brazil Details
Hospital de Cancer de Barretos ACTIVE_NOT_RECRUITING Barretos SP 14784-400 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP ACTIVE_NOT_RECRUITING Sao Paulo SP 01246-000 Brazil Details
Beijing Union Hospital COMPLETED Beijing 100730 China Details
Jilin Cancer Hospital ACTIVE_NOT_RECRUITING Changchun 132013 China Details
Hunan Cancer Hospital ACTIVE_NOT_RECRUITING Changsha CITY 410013 China Details
The Second Xiangya Hospital of Central South University ACTIVE_NOT_RECRUITING Changsha 410011 China Details
Sichuan Provincial Cancer Hospital WITHDRAWN Chengdu 610041 China Details
West China Hospital, Sichuan University ACTIVE_NOT_RECRUITING Chengdu 610041 China Details
The First Affiliated Hospital of Guangzhou Medical University ACTIVE_NOT_RECRUITING Guangzhou 510120 China Details
Harbin Medical University Cancer Hospital ACTIVE_NOT_RECRUITING Harbin 150081 China Details
Affiliated Hospital of Jining Medical University ACTIVE_NOT_RECRUITING Jining 272029 China Details
Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School COMPLETED Nanjing City 210008 China Details
Guangxi Cancer Hospital of Guangxi Medical University ACTIVE_NOT_RECRUITING Nanning City 530021 China Details
Shanghai Pulmonary Hospital ACTIVE_NOT_RECRUITING Shanghai 200433 China Details
Taihe Hospital of Hubei University of Medicine ACTIVE_NOT_RECRUITING Shiyan 442000 China Details
Union Hospital Tongji Medical College Huazhong University of Science and Technology ACTIVE_NOT_RECRUITING Wuhan City 430023 China Details
Clinical Hospital Centre Zagreb RECRUITING Zagreb 10000 Croatia Details
Institut Bergonie; Pneumology ACTIVE_NOT_RECRUITING Bordeaux 33076 France Details
CHRU Lille ACTIVE_NOT_RECRUITING Lille 59037 France Details
Centre Leon Berard RECRUITING Lyon 69008 France Details
Hopital Nord AP-HM ACTIVE_NOT_RECRUITING Marseille 13015 France Details
CHU Rennes - Hopital Pontchaillou RECRUITING Rennes cedex 09 35033 France Details
Hopital Larrey; Pneumologie ACTIVE_NOT_RECRUITING Toulouse 31059 France Details
Hopital Robert Schuman; Pneumologie RECRUITING Vantoux 57070 France Details
HELIOS Klinikum Emil von Behring Klinik f.Pneumologie Onkologie u.Infektiologie RECRUITING Berlin 14165 Germany Details
Kliniken Maria Hilf; Klinik für Hämatologie, Onkologie und Gastroenterologie RECRUITING Mönchengladbach 41063 Germany Details
Pius-Hospital; Klinik fuer Haematologie und Onkologie RECRUITING Oldenburg 26121 Germany Details
Uoa Sotiria Hospital; Oncology RECRUITING Athens 115 27 Greece Details
Metropolitan Hospital RECRUITING Athens 185 47 Greece Details
University Hospital of Larissa;Department of Medical Oncology RECRUITING Larissa 411 10 Greece Details
Euromedical General Clinic of Thessaloniki; Oncology Department RECRUITING Thessaloniki 546 45 Greece Details
American Oncology Institute WITHDRAWN Hyderabad Andhra Pradesh 500019 India Details
All India Institute Of Medical Sciences (AIIMS) RECRUITING New Delhi Delhi 110029 India Details
MVR Cancer Centre and Research Institute ACTIVE_NOT_RECRUITING Kozhikode Kerala 673601 India Details
MOC Cancer Care & Research Centre (Unit of Cellcure Cancer Centre Pvt Ltd) ACTIVE_NOT_RECRUITING Mumbai Maharashtra 400036 India Details
MOC Cancer Care & Research Centre WITHDRAWN Mumbai Maharashtra 400036 India Details
Christian Medical College WITHDRAWN Ranipet Tamil NADU 632513 India Details
Mahamana Pandit Madan Mohan Malaviya Cancer Centre-TMC RECRUITING Varanasi Uttar Pradesh 221005 India Details
Tata Medical Center; Department of Medical Oncology RECRUITING Kolkata WEST Bengal 700160 India Details
Postgraduate Institute of Medical Education and Research WITHDRAWN Chandigarh 160012 India Details
Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale RECRUITING Napoli Campania 80131 Italy Details
IRCCS Istituto Regina Elena (IFO); Oncologia Medica B ACTIVE_NOT_RECRUITING Roma Lazio 00144 Italy Details
Azienda Ospedaliera San Camillo Forlanini; U.O.C. Pneumologia Ad Indirizzo Oncologico 1 ACTIVE_NOT_RECRUITING Roma Lazio 00152 Italy Details
IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A ACTIVE_NOT_RECRUITING Genova Liguria 16132 Italy Details
Irccs Istituto Europeo di Oncologia (IEO); Divisione di Oncologia WITHDRAWN Milano Lombardia 20141 Italy Details
Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia RECRUITING Milano Lombardia 20162 Italy Details
ASST DI MONZA; Oncologia Medica RECRUITING Monza Lombardia 20900 Italy Details
Azienda Sanitaria Ospedaliera S Luigi Gonzaga; SSD Oncologia Polomonare (II PAD. IV PIANO) RECRUITING Orbassano Piemonte 10043 Italy Details
Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello; Dipartimento Cardio Toraco Vascolare RECRUITING Pisa Toscana 56124 Italy Details
IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Seconda ACTIVE_NOT_RECRUITING Padova Veneto 35128 Italy Details
King Hussein Cancer Center ACTIVE_NOT_RECRUITING Amman 11941 Jordan Details
Hotel Dieu de France RECRUITING Beirut Lebanon Details
Hospital Civil de Guadalajara Fray Antonio Alcalde RECRUITING Guadalajara Jalisco 44280 Mexico Details
Health Pharma Professional Research ACTIVE_NOT_RECRUITING Cdmx Mexico CITY (federal District) 03100 Mexico Details
Superare; Centro de Infusion WITHDRAWN Ciudad de México Mexico CITY (federal District) 06760 Mexico Details
Hospital Universitario; Dr. Jose E. Gonzalez RECRUITING Monterrey Nuevo LEON 64460 Mexico Details
NKI/AvL ACTIVE_NOT_RECRUITING Amsterdam 1066 CX Netherlands Details
UMC St Radboud ACTIVE_NOT_RECRUITING Nijmegen 6525 GA Netherlands Details
Erasmus MC ACTIVE_NOT_RECRUITING Rotterdam 3015 GD Netherlands Details
Amethyst Cluj; Medical Oncology RECRUITING Cluj County 407280 Romania Details
Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj Napoca; Oncologie Medicala RECRUITING Cluj Napoca 400015 Romania Details
Centrul de Oncologie Sfantul Nectarie RECRUITING Craiova 200347 Romania Details
Institutul Regional de Oncologie Iasi WITHDRAWN Iasi 700483 Romania Details
Emergency County Clinical Hospital Ploiesti; Medical oncology RECRUITING Ploiesti Romania Details
Centrul de Oncologie Oncohelp RECRUITING Timisoara 300239 Romania Details
AV Medical Ltd. COMPLETED Sait-Petersburg Sankt Petersburg Sankt Petersburg 196006 Russian Federation Details
Univerzitna nemocnica Bratislava; Oddelenie Klinickej Onkologie, Klinika Pneumologie A Ftizeologie RECRUITING Bratislava 826 06 Slovakia Details
Vychodoslovensky onkologicky ustav WITHDRAWN Kosice 041 91 Slovakia Details
Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia RECRUITING A Coruña LA Coruña 15006 Spain Details
Hospital del Mar; Servicio de Oncologia ACTIVE_NOT_RECRUITING Barcelona 08003 Spain Details
Institut Catala d Oncologia Hospital Duran i Reynals ACTIVE_NOT_RECRUITING Barcelona 08908 Spain Details
Hospital Ramon y Cajal; Servicio de Oncologia RECRUITING Madrid 28034 Spain Details
Hospital Regional Universitario Carlos Haya; Servicio de Oncologia ACTIVE_NOT_RECRUITING Malaga 29011 Spain Details
Karolinska Universitetssjukhuset, Solna; Kliniska prövningsenheten Z:4:01 RECRUITING Stockholm 171 76 Sweden Details
Chulalongkorn Hospital; Medical Oncology RECRUITING Bangkok 10330 Thailand Details
Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology RECRUITING Bangkok 10700 Thailand Details
Prapokklao Hospital RECRUITING Chanthaburi 22000 Thailand Details
Songklanagarind Hospital; Department of Internal Medicine, Division of Respiratory RECRUITING Songkhla 90110 Thailand Details
Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology WITHDRAWN Adana 01230 Turkey Details
Gazi University Medical Faculty, Oncology Hospital ACTIVE_NOT_RECRUITING Ankara 06500 Turkey Details
Liv Hospital Ankara; Medical Oncology ACTIVE_NOT_RECRUITING Ankara 06680 Turkey Details
Ege Uni Medical Faculty Hospital; Oncology Dept WITHDRAWN Izmir 35100 Turkey Details
Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department WITHDRAWN Malatya 44280 Turkey Details
Ac?badem Maslak Hastanesi Büyükdere WITHDRAWN Sar?yer/?stanbul 34457 Turkey Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field