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| NCT ID | NCT04603807 |
| Title | A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Hoffmann-La Roche |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | TUR | SWE | SVK | ROU | NLD | LBN | ITA | HRV | GRC | FRA | ESP | DEU | BRA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Ac?badem Maslak Hastanesi Büyükdere | WITHDRAWN | Sar?yer/?stanbul | 34457 | Turkey | Details | |
| Affiliated Hospital of Jining Medical University | ACTIVE_NOT_RECRUITING | Jining | 272029 | China | Details | |
| All India Institute Of Medical Sciences (AIIMS) | RECRUITING | New Delhi | Delhi | 110029 | India | Details |
| American Oncology Institute | WITHDRAWN | Hyderabad | Andhra Pradesh | 500019 | India | Details |
| Amethyst Cluj | RECRUITING | Cluj County | 407280 | Romania | Details | |
| Asst Di Monza | WITHDRAWN | Monza | Lombardia | 20900 | Italy | Details |
| Asst Grande Ospedale Metropolitano Niguarda | RECRUITING | Milano | Lombardia | 20162 | Italy | Details |
| AV Medical Ltd. | WITHDRAWN | Sankt-peterburg | Leningrad | 199034 | Russian Federation | Details |
| Azienda Ospedaliera San Camillo Forlanini | ACTIVE_NOT_RECRUITING | Roma | Lazio | 00152 | Italy | Details |
| Azienda Ospedaliera Universitaria Pisana - Ospedale Cisanello | WITHDRAWN | Pisa | Toscana | 56124 | Italy | Details |
| Azienda Sanitaria Ospedaliera S Luigi Gonzaga | RECRUITING | Orbassano | Piemonte | 10043 | Italy | Details |
| Bangkok Metropolitan Administration Medical College and Vajira Hospital | RECRUITING | Wachira Phayaban | 10300 | Thailand | Details | |
| Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital | WITHDRAWN | Adana | 01250 | Turkey | Details | |
| Beijing Union Hospital | WITHDRAWN | Beijing | 100730 | China | Details | |
| Centre Leon Berard | RECRUITING | Lyon | 69008 | France | Details | |
| Centro de Pesquisa e Ensino em Oncologia de Santa Catarina - CEPEN | RECRUITING | Florianopolis | Santa Catarina | 88020-210 | Brazil | Details |
| Centrul de Oncologie Oncohelp | RECRUITING | Timisoara | 300239 | Romania | Details | |
| Centrul de Oncologie Sfantul Nectarie | RECRUITING | Craiova | 200542 | Romania | Details | |
| CHRU Lille | ACTIVE_NOT_RECRUITING | Lille | 59037 | France | Details | |
| CHU Rennes - Hopital Pontchaillou | RECRUITING | Rennes cedex 09 | 35033 | France | Details | |
| Chulalongkorn Hospital | RECRUITING | Bangkok | 10330 | Thailand | Details | |
| Clinical Hospital Centre Zagreb | RECRUITING | Zagreb | 10000 | Croatia | Details | |
| Complejo Hospitalario Universitario A Coruña (CHUAC) | RECRUITING | La Coruna | 15006 | Spain | Details | |
| Ege Uni Medical Faculty Hospital | WITHDRAWN | Izmir | 35100 | Turkey | Details | |
| Emergency County Clinical Hospital Ploiesti | RECRUITING | Ploiesti | Romania | Details | ||
| Erasmus MC | ACTIVE_NOT_RECRUITING | Rotterdam | 3015 GD | Netherlands | Details | |
| Euromedical General Clinic of Thessaloniki | RECRUITING | Thessaloniki | 546 45 | Greece | Details | |
| Faculty of Med. Siriraj Hosp. | RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Gazi University Medical Faculty, Oncology Hospital | ACTIVE_NOT_RECRUITING | Ankara | 06500 | Turkey | Details | |
| Guangxi Cancer Hospital of Guangxi Medical University | ACTIVE_NOT_RECRUITING | Nanning | 530021 | China | Details | |
| Harbin Medical University Cancer Hospital | ACTIVE_NOT_RECRUITING | Harbin | 150081 | China | Details | |
| Health Pharma Professional Research | ACTIVE_NOT_RECRUITING | Cdmx | Mexico CITY (federal District) | 03100 | Mexico | Details |
| HELIOS Klinikum Emil von Behring Klinik f.Pneumologie Onkologie u.Infektiologie | RECRUITING | Berlin | 14165 | Germany | Details | |
| Hopital Larrey | ACTIVE_NOT_RECRUITING | Toulouse | 31059 | France | Details | |
| Hopital Nord AP-HM | ACTIVE_NOT_RECRUITING | Marseille | 13015 | France | Details | |
| Hopital Robert Schuman | RECRUITING | Vantoux | 57070 | France | Details | |
| Hospitais Integrados da Gavea S/A | ACTIVE_NOT_RECRUITING | Brasilia | Distrito Federal | 70390-140 | Brazil | Details |
| Hospital Civil de Guadalajara Fray Antonio Alcalde | RECRUITING | Guadalajara | Jalisco | 44280 | Mexico | Details |
| Hospital de Cancer de Barretos | ACTIVE_NOT_RECRUITING | Barretos | São Paulo | 14784-400 | Brazil | Details |
| Hospital del Mar | ACTIVE_NOT_RECRUITING | Barcelona | 08003 | Spain | Details | |
| Hospital Ramon y Cajal | RECRUITING | Madrid | 28034 | Spain | Details | |
| Hospital Regional Universitario Carlos Haya | ACTIVE_NOT_RECRUITING | Malaga | 29010 | Spain | Details | |
| Hospital Sao Rafael - HSR | RECRUITING | Salvador | Bahia | 41253-190 | Brazil | Details |
| Hospital Universitario | RECRUITING | Monterrey | Nuevo LEON | 64460 | Mexico | Details |
| Hotel Dieu de France | RECRUITING | Beirut | Lebanon | Details | ||
| Hunan Cancer Hospital | ACTIVE_NOT_RECRUITING | Changsha City | 410013 | China | Details | |
| Inonu University Medical Faculty Turgut Ozal Medical Center Medical Oncology Department | WITHDRAWN | Malatya | 44280 | Turkey | Details | |
| Institut Bergonie | ACTIVE_NOT_RECRUITING | Bordeaux | 33076 | France | Details | |
| Institut Catala d Oncologia Hospital Duran i Reynals | ACTIVE_NOT_RECRUITING | Barcelona | 08908 | Spain | Details | |
| Instituto do Cancer do Estado de Sao Paulo - ICESP | ACTIVE_NOT_RECRUITING | Sao Paulo | São Paulo | 01246-000 | Brazil | Details |
| Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj Napoca | RECRUITING | Cluj Napoca | 400015 | Romania | Details | |
| Irccs Istituto Europeo di Oncologia (IEO) | WITHDRAWN | Milano | Lombardia | 20141 | Italy | Details |
| IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST) | ACTIVE_NOT_RECRUITING | Genova | Liguria | 16132 | Italy | Details |
| IRCCS Istituto Oncologico Veneto (IOV) | ACTIVE_NOT_RECRUITING | Padova | Veneto | 35128 | Italy | Details |
| IRCCS Istituto Regina Elena (IFO) | ACTIVE_NOT_RECRUITING | Roma | Lazio | 00144 | Italy | Details |
| Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale | RECRUITING | Napoli | Campania | 80131 | Italy | Details |
| Jilin Cancer Hospital | ACTIVE_NOT_RECRUITING | Changchun | 132013 | China | Details | |
| Karolinska Universitetssjukhuset, Solna | RECRUITING | Stockholm | 171 76 | Sweden | Details | |
| King Hussein Cancer Center | ACTIVE_NOT_RECRUITING | Amman | 1269 | Jordan | Details | |
| Kliniken Maria Hilf | RECRUITING | Mönchengladbach | 41063 | Germany | Details | |
| Liv Hospital Ankara | ACTIVE_NOT_RECRUITING | Ankara | 06680 | Turkey | Details | |
| Mahamana Pandit Madan Mohan Malaviya Cancer Centre-TMC | RECRUITING | Varanasi | Uttar Pradesh | 221005 | India | Details |
| Medical Park Seyhan Hospital | RECRUITING | Seyhan | 01140 | Turkey | Details | |
| Metropolitan Hospital | RECRUITING | Athens | 185 47 | Greece | Details | |
| MOC Cancer Care & Research Centre (Unit of Cellcure Cancer Centre Pvt Ltd) | ACTIVE_NOT_RECRUITING | Mumbai | Maharashtra | 400036 | India | Details |
| MVR Cancer Centre and Research Institute | ACTIVE_NOT_RECRUITING | Kozhikode | Kerala | 673601 | India | Details |
| Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School | COMPLETED | Nanjing City | 210008 | China | Details | |
| NKI/AvL | ACTIVE_NOT_RECRUITING | Amsterdam | 1066 CX | Netherlands | Details | |
| Oncocentro Belo Horizonte | WITHDRAWN | Belo Horizonte | Minas Gerais | 30360-680 | Brazil | Details |
| Oncocentro Serviços Médicos e Hospitalares Ltda | RECRUITING | Fortaleza | Ceará | 60130-241 | Brazil | Details |
| Oncoclinicas Rio de Janeiro S.A. | COMPLETED | Rio de Janeiro | 22250-905 | Brazil | Details | |
| Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda | WITHDRAWN | Ijui | Rio Grande Do Sul | 98700-000 | Brazil | Details |
| Pius-Hospital | RECRUITING | Oldenburg | 26121 | Germany | Details | |
| Postgraduate Institute of Medical Education and Research | WITHDRAWN | Chandigarh | 160012 | India | Details | |
| Prapokklao Hospital | RECRUITING | Chanthaburi | 22000 | Thailand | Details | |
| Shanghai Pulmonary Hospital | ACTIVE_NOT_RECRUITING | Shanghai | 200433 | China | Details | |
| Songklanagarind Hospital | RECRUITING | Songkhla | 90110 | Thailand | Details | |
| SUPERARE | WITHDRAWN | Ciudad de México | Mexico CITY (federal District) | 06760 | Mexico | Details |
| Taihe Hospital of Hubei University of Medicine | ACTIVE_NOT_RECRUITING | Shiyan | 442000 | China | Details | |
| Tata Medical Center | RECRUITING | Kolkata | WEST Bengal | 700160 | India | Details |
| The First Affiliated Hospital of Guangzhou Medical University | ACTIVE_NOT_RECRUITING | Guangzhou | 510120 | China | Details | |
| The Second Xiangya Hospital of Central South University | ACTIVE_NOT_RECRUITING | Changsha | 410011 | China | Details | |
| UMC St Radboud | ACTIVE_NOT_RECRUITING | Nijmegen | 6525 GA | Netherlands | Details | |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology | ACTIVE_NOT_RECRUITING | Wuhan City | 430023 | China | Details | |
| Universitaetsklinikum Giessen und Marburg GmbH | RECRUITING | Gießen | 35392 | Germany | Details | |
| University Hospital of Larissa | ACTIVE_NOT_RECRUITING | Larissa | 411 10 | Greece | Details | |
| Universitätsklinikum Hamburg-Eppendorf | RECRUITING | Hamburg | 20246 | Germany | Details | |
| Univerzitna nemocnica Bratislava | RECRUITING | Bratislava | 826 06 | Slovakia | Details | |
| Uoa Sotiria Hospital | RECRUITING | Athens | 115 27 | Greece | Details | |
| Vychodoslovensky onkologicky ustav | WITHDRAWN | Košice | 040 01 | Slovakia | Details | |
| West China Hospital, Sichuan University | ACTIVE_NOT_RECRUITING | Chengdu | 610041 | China | Details |
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