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NCT ID NCT04700124
Title Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304) (KEYNOTE-B15)
Acronym KEYNOTE-B15
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications
Therapies
Age Groups: adult | senior
Covered Countries USA | ROU | POL | ITA | ISR | HUN | HRV | GRC | GBR | FRA | ESP | DEU | CZE | CAN | BGR | AUS | ARG

Facility Status City State Zip Country Details
Mayo Clinic in Arizona - Phoenix ( Site 0043) Phoenix Arizona 85054 United States Details
St Joseph Heritage Healthcare-Oncology ( Site 0035) Fullerton California 92835 United States Details
UCLA Hematology/Oncology - Westwood (Building 200 Suite 140)-Department of Urology/Institute of Uro Los Angeles California 90095 United States Details
University of California San Francisco ( Site 0010) San Francisco California 94158 United States Details
Stanford University ( Site 0023) Stanford California 94305-5826 United States Details
University of Colorado, Anschutz Cancer Pavilion ( Site 0009) Aurora Colorado 80045 United States Details
UF Health ( Site 0031) Gainesville Florida 32608 United States Details
Indiana University Melvin and Bren Simon Cancer Center ( Site 0050) Indianapolis Indiana 46202 United States Details
University of Iowa Hospital and Clinics ( Site 0029) Iowa City Iowa 52242 United States Details
University of Louisville, James Graham Brown Cancer Center ( Site 0022) Louisville Kentucky 40202 United States Details
Icahn School of Medicine at Mount Sinai ( Site 0011) New York New York 10029 United States Details
White Plains Hospital ( Site 0039) White Plains New York 10601 United States Details
Duke University Medical Center ( Site 0017) Durham North Carolina 27710 United States Details
Wake Forest Baptist Health ( Site 0014) Winston-Salem North Carolina 27157 United States Details
Oregon Health and Science University ( Site 0028) Portland Oregon 97239-3011 United States Details
MidLantic Urology ( Site 0002) Bala-Cynwyd Pennsylvania 19004 United States Details
Saint Francis Cancer Center ( Site 0008) Greenville South Carolina 29607 United States Details
The University of Tennessee Medical Center ( Site 0034) Knoxville Tennessee 37920 United States Details
UT Southwestern Medical Center ( Site 0003) Dallas Texas 75390 United States Details
Houston Methodist Urology Associates ( Site 0033) Houston Texas 77030 United States Details
Urology of San Antonio ( Site 0020) San Antonio Texas 78229 United States Details
University of Wisconsin Hospital and Clinics ( Site 0037) Madison Wisconsin 53792 United States Details
Hospital Británico de Buenos Aires-Oncology ( Site 1551) Ciudad autónoma de Buenos Aires Buenos Aires 1280 Argentina Details
Hospital Italiano de Buenos Aires ( Site 1554) ABB Caba C1199ABB Argentina Details
Centro de Educación Médica e Investigaciones Clínicas (CEMIC) ( Site 1558) Buenos Aires Caba C1431FWO Argentina Details
Fundacion Estudios Clinicos-Oncology ( Site 1557) Rosario Santa Fe 2000 Argentina Details
Centro de Urología (CDU) ( Site 1552) Buenos Aires 1120 Argentina Details
Asociación de Beneficencia Hospital Sirio Libanés ( Site 1553) Buenos Aires C1419AHN Argentina Details
Macquarie University-MQ Health Clinical Trials Unit ( Site 1259) Macquarie University New South Wales 2109 Australia Details
Mater Hospital Brisbane ( Site 1257) South Brisbane Queensland 4101 Australia Details
Lyell McEwin Hospital ( Site 1252) Elizabeth Vale South Australia 5112 Australia Details
Frankston Hospital-Oncology and Haematology ( Site 1258) Frankston Victoria 3199 Australia Details
MHAT "Uni Hospital" OOD ( Site 1154) Panagyurishte Pazardzhik 4500 Bulgaria Details
Complex Oncology Center Plovdiv ( Site 1151) Plovdiv 4000 Bulgaria Details
MHAT Central Onco Hospital OOD ( Site 1158) Plovdiv 4000 Bulgaria Details
MHAT Serdika ( Site 1152) Sofia 1632 Bulgaria Details
BC Cancer - Vancouver Center ( Site 0110) Vancouver British Columbia V5Z 4E6 Canada Details
CancerCare Manitoba ( Site 0108) Winnipeg Manitoba R3E 0V9 Canada Details
Moncton Hospital ( Site 0107) Moncton New Brunswick E1C 6Z8 Canada Details
Ottawa Hospital Research Institute ( Site 0109) Ottawa Ontario K1H 8L6 Canada Details
Jewish General Hospital ( Site 0106) Montreal Quebec H3T 1E2 Canada Details
SUN YAT-SEN UNIVERSITY CANCER CENTRE ( Site 1406) Guangzhou Guangdong 510060 China Details
Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 1413) Guangzhou Guangdong 510120 China Details
Hunan Cancer Hospital ( Site 1403) Changsha Hunan 410013 China Details
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S Nanjing Jiangsu 210000 China Details
Nantong Tumor Hospital-Urology ( Site 1405) Nantong Jiangsu 226361 China Details
Fudan University Shanghai Cancer Center-Urology department ( Site 1401) Shanghai Shanghai 200032 China Details
Renji Hospital Shanghai Jiao Tong University School of Medicine ( Site 1402) Shanghai Shanghai 200127 China Details
Fundación Colombiana de Cancerología Clínica Vida ( Site 1653) Medellin Antioquia 050030 Colombia Details
Oncomédica S.A.S ( Site 1652) Montería Cordoba 230002 Colombia Details
Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia-Center Investigator ( Site 1654) Bogota Distrito Capital De Bogota 111321 Colombia Details
Fundación Cardiovascular de Colombia-Santander ( Site 1657) Piedecuesta Santander 681017 Colombia Details
Fundacion Valle del Lili- CIC ( Site 1656) Cali Valle Del Cauca 760032 Colombia Details
Klinički bolnički centar Sestre milosrdnice ( Site 1703) Zagreb Grad Zagreb 10000 Croatia Details
Klinički bolnički centar Zagreb-Klinika za onkologiju ( Site 1701) Zagreb Grad Zagreb 10000 Croatia Details
Klinički bolnički centar Osijek ( Site 1705) Osijek Osjecko-baranjska Zupanija 31000 Croatia Details
Klinički Bolnički Centar Split-Oncology and Radiotherapy ( Site 1702) Split Splitsko-dalmatinska Zupanija 21000 Croatia Details
Fakultni nemocnice u sv. Anny v Brne ( Site 0253) Brno Jihomoravsky Kraj 656 91 Czechia Details
Fakultni nemocnice Hradec Kralove-Klinika onkologie a radioterapie ( Site 0254) Hradec Kralove 500 05 Czechia Details
Fakultni Nemocnice Olomouc ( Site 0251) Olomouc 779 00 Czechia Details
Fakultni Thomayerova nemocnice ( Site 0252) Praha 4 140 59 Czechia Details
CHU La Timone ( Site 0456) Marseille Bouches-du-Rhone 13005 France Details
CHU Jean Minjoz ( Site 0453) Besancon Doubs 25000 France Details
CHU de Brest -Site Hopital Morvan ( Site 0461) Brest Finistere 29200 France Details
Institut Universitaire du Cancer Toulouse - Oncopole ( Site 0455) Toulouse Haute-Garonne 31059 France Details
CHU Limoges Hopital Dupuytren ( Site 0459) Limoges Haute-Vienne 87042 France Details
Gustave Roussy ( Site 0467) Villejuif Ile-de-France 94800 France Details
CHU GRENOBLE ALPES ( Site 0468) La Tronche Isere 38700 France Details
Centre Hospitalier Regional du Orleans ( Site 0463) Orleans Loiret 45067 France Details
Polyclinique du Bois ( Site 0458) Lille Nord 59000 France Details
Hopital Diaconesses Croix Saint Simon ( Site 0465) Paris 75020 France Details
Universitaetsklinikum Freiburg ( Site 0512) Freiburg Baden-Wurttemberg 79106 Germany Details
Universitaetsklinik fuer Urologie ( Site 0501) Tuebingen Baden-Wurttemberg 72076 Germany Details
Caritas Krankenhaus St. Josef ( Site 0502) Regensburg Bayern 93053 Germany Details
Universitaetsklinikum Wuerzburg ( Site 0520) Wuerzburg Bayern 97080 Germany Details
Kath. Krankenhaus Marienhospital. Universitaetsklinik ( Site 0511) Herne Nordrhein-Westfalen 44625 Germany Details
Universitaetsklinikum Muenster ( Site 0516) Muenster Nordrhein-Westfalen 48149 Germany Details
Krankenhaus Martha Maria Halle-Doelau ( Site 0507) Halle Sachsen-Anhalt 06120 Germany Details
Universitaetsklinikum Carl Gustav Carus ( Site 0509) Dresden Sachsen 01307 Germany Details
Vivantes Klinikum Am Urban ( Site 0519) Berlin 10967 Germany Details
UNIVERSITY HOSPITAL OF PATRAS-DIVISION OF ONCOLOGY ( Site 0305) Patras Achaia 26504 Greece Details
General Hospital of Athens "Alexandra" ( Site 0303) Athens Attiki 115 28 Greece Details
Athens Medical Center ( Site 0304) Athens Attiki 151 25 Greece Details
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 0301) Chaidari Attiki 124 62 Greece Details
University General Hospital of Larissa ( Site 0302) Larissa Thessalia 411 10 Greece Details
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ ( Site 1010) Szeged Csongrad 6720 Hungary Details
Jász-Nagykun-Szolnok Vármegyei Hetényi Géza Kórház ( Site 1002) Szolnok Jasz-Nagykun-Szolnok 5000 Hungary Details
Debreceni Egyetem Klinikai Kozpont ( Site 1006) Debrecen 4032 Hungary Details
Rambam Health Care Campus-Oncology ( Site 0751) Haifa 3109601 Israel Details
Hadassah Medical Center-Oncology ( Site 0757) Jerusalem 9112001 Israel Details
Meir Medical Center-oncology ( Site 0754) Kfar Saba 4428164 Israel Details
Rabin Medical Center-Oncology ( Site 0752) Petah-Tikva 4941492 Israel Details
Sheba Medical Center-ONCOLOGY ( Site 0753) Ramat Gan 5262100 Israel Details
Sourasky Medical Center-Oncology ( Site 0755) Tel Aviv 6423906 Israel Details
Yitzhak Shamir Medical Center-Oncology ( Site 0756) Zerifin 70300 Israel Details
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 0588) Milan Lombardia 20133 Italy Details
Presidio Ospedaliero Santa Maria delle Grazie ( Site 0599) Pozzuoli Napoli 80078 Italy Details
AOU San Luigi Gonzaga di Orbassano ( Site 0595) Orbassano Torino 10043 Italy Details
Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento ( Site 0598) Verona Veneto 37126 Italy Details
Azienda Ospedaliero Universitaria delle Marche-Clinica Oncologica ( Site 0593) Ancona 60126 Italy Details
Ospedale Cannizzaro ( Site 0590) Catania 95126 Italy Details
IRCCS Ospedale San Raffaele ( Site 0596) Milano 20132 Italy Details
Istituto Oncologico Veneto IRCCS-Oncologia Medica 1 ( Site 0600) Padova 35128 Italy Details
Nagoya University Hospital ( Site 1512) Nagoya Aichi 466-8560 Japan Details
Hirosaki University Hospital ( Site 1501) Hirosaki Aomori 036-8563 Japan Details
University of Tsukuba Hospital ( Site 1502) Tsukuba Ibaraki 305-8576 Japan Details
Kanazawa University Hospital ( Site 1509) Kanazawa Ishikawa 920-8641 Japan Details
Kitasato University Hospital ( Site 1506) Sagamihara Kanagawa 252-0375 Japan Details
Yokohama City University Medical Center ( Site 1508) Yokohama Kanagawa 232-0024 Japan Details
Kanagawa Cancer Center ( Site 1507) Yokohama Kanagawa 241-8515 Japan Details
Tohoku University Hospital ( Site 1503) Sendai Miyagi 980-8574 Japan Details
Hamamatsu University Hospital ( Site 1511) Hamamatsu Shizuoka 431-3192 Japan Details
Gifu University Hospital ( Site 1513) Gifu 501-1194 Japan Details
Nagasaki University Hospital ( Site 1517) Nagasaki 852-8510 Japan Details
Okayama University Hospital ( Site 1516) Okayama 700-8558 Japan Details
Osaka International Cancer Institute ( Site 1514) Osaka 541-8567 Japan Details
Osaka Metropolitan University Hospital ( Site 1515) Osaka 545-8586 Japan Details
Tokyo Medical and Dental University Hospital ( Site 1505) Tokyo 113-8519 Japan Details
Keio University Hospital ( Site 1504) Tokyo 160-8582 Japan Details
Toyama University Hospital ( Site 1510) Toyama 930-0194 Japan Details
Chonnam National University Hwasun Hospital ( Site 1353) Jeollanam-do Jeonranamdo 58128 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 1355) Gyeonggi-do Kyonggi-do 13620 Korea, Republic of Details
Asan Medical Center ( Site 1352) Songpagu Seoul 05505 Korea, Republic of Details
Kyungpook National University Chilgok Hospital ( Site 1354) Daegu Taegu-Kwangyokshi 41404 Korea, Republic of Details
Gachon University Gil Medical Center ( Site 1356) Incheon 21565 Korea, Republic of Details
Korea University Anam Hospital ( Site 1357) Seoul 02841 Korea, Republic of Details
Seoul National University Hospital ( Site 1351) Seoul 03080 Korea, Republic of Details
University Malaya Medical Centre ( Site 0352) Lembah Pantai Kuala Lumpur 59100 Malaysia Details
Hospital Pulau Pinang ( Site 0355) George Town Pulau Pinang 10990 Malaysia Details
Sarawak General Hospital ( Site 0351) Kuching Sarawak 93586 Malaysia Details
Sunway Medical Centre ( Site 0353) Petaling Jaya Selangor 47500 Malaysia Details
THE MEDICAL CITY ILOILO-The Medical City Iloilo - Clinical and Translational Research Institute-Ilo Iloilo City Iloilo 5000 Philippines Details
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu ( Site 1058) Wrocław Dolnoslaskie 50-556 Poland Details
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 1057) Siedlce Mazowieckie 08-110 Poland Details
Narodowy Instytut Onkologii ( Site 1051) Warszawa Mazowieckie 02-781 Poland Details
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 1053) Przemysl Podkarpackie 37-700 Poland Details
Clinical Research Center Medic-R ( Site 1061) Poznan Wielkopolskie 61-731 Poland Details
Szpital Wojewodzki im. Mikolaja Kopernika ( Site 1055) Koszalin Zachodniopomorskie 75-581 Poland Details
Centro Hospitalar e Universitario de Coimbra ( Site 0406) Coimbra 3000-075 Portugal Details
Inst. Portugues de Oncologia de Lisboa Francisco Gentil EPE ( Site 0409) Lisboa 1099-023 Portugal Details
CHLO, EPE - Hospital de Sao Francisco Xavier ( Site 0401) Lisboa 1449-005 Portugal Details
Hospital Geral de Santo Antonio ( Site 0408) Porto 4099-001 Portugal Details
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1102) Cluj Napoca Cluj 400015 Romania Details
Cardiomed SRL Cluj-Napoca ( Site 1101) Cluj-Napoca Cluj 400015 Romania Details
Institutul Oncologic Prof.Dr. Ion Chiricuta Cluj-Napoca ( Site 1103) Cluj-Napoca Cluj 400015 Romania Details
SC Radiotherapy Center Cluj SRL ( Site 1108) Comuna Floresti Cluj 407280 Romania Details
S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 1107) Craiova Dolj 200542 Romania Details
Policlinica Oncomed SRL ( Site 1106) Timisoara Timis 300239 Romania Details
SC Focus Lab Plus SRL ( Site 1104) Bucuresti 022548 Romania Details
Institutul Oncologic Cluj-Oncologie Medicala ( Site 1109) Cluj 400015 Romania Details
Altay Regional Oncology Dispensary ( Site 0851) Barnaul Altayskiy Kray 656040 Russian Federation Details
National Medical Research Radiology Centre ( Site 0869) Obninsk Kaluzskaja Oblast 249036 Russian Federation Details
National Medical Research Centre of Oncology named after N.N. Blokhin ( Site 0865) Moscow Moskva 115230 Russian Federation Details
First Moscow State Medical University n.a. I.M.Sechenov ( Site 0871) Moscow Moskva 119991 Russian Federation Details
Volga District Medical Center ( Site 0876) Nizhny Novgorod Nizhegorodskaya Oblast 603074 Russian Federation Details
St.Petersburg Clinical Hospital RAS ( Site 0864) Saint Petersburg Sankt-Peterburg 194017 Russian Federation Details
St.Petersburg State Medical Univ. n.a. acad. I.P.Pavlov ( Site 0856) Saint Petersburg Sankt-Peterburg 197101 Russian Federation Details
Scientific Research Oncology Institute n.a. N.N.Petrov ( Site 0852) Saint Petersburg Sankt-Peterburg 197758 Russian Federation Details
Sverdlovsk Regional Oncology Hospital ( Site 0867) Ekaterinburg Sverdlovskaya Oblast 620036 Russian Federation Details
Sverdlovsky Regional Clinical hospital #1 ( Site 0868) Ekaterinburg Sverdlovskaya Oblast 620102 Russian Federation Details
Volgograd Regional Uronephrological Center ( Site 0870) Volzhsky Volgogradskaya Oblast 404120 Russian Federation Details
Tan Tock Seng Hospital ( Site 0704) Singapore Central Singapore 308442 Singapore Details
Wits Clinical Research ( Site 0603) Johannesburg Gauteng 2193 South Africa Details
Steve Biko Academic Hospital ( Site 0601) Pretoria Gauteng 0002 South Africa Details
Groote Schuur Hospital ( Site 0602) Cape Town Western Cape 7925 South Africa Details
Hospital Universitario Central de Asturias ( Site 0654) Oviedo Asturias 33011 Spain Details
Hospital Germans Trias i Pujol. ICO de Badalona ( Site 0658) Badalona Barcelona 08916 Spain Details
Xarxa Assistencial Universitaria Manresa ( Site 0655) Manresa Barcelona 08243 Spain Details
Institut Català d'Oncologia (ICO) - Girona ( Site 0653) Girona Gerona 17007 Spain Details
CHUS - Hospital Clinico Universitario-Servicio de Oncologia ( Site 0660) Santiago de Compostela La Coruna 15706 Spain Details
Hospital Universitario Insular de Gran Canaria ( Site 0657) Las Palmas de Gran Canaria Las Palmas 35001 Spain Details
Fundación Instituto Valenciano de Oncología-Oncologico ( Site 0662) Valencia Valenciana, Comunitat 46009 Spain Details
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 0661) Barcelona 08035 Spain Details
Hospital Clinico Universitario San Carlos de Madrid ( Site 0651) Madrid 28040 Spain Details
Hospital Virgen del Rocio ( Site 0659) Sevilla 41013 Spain Details
Chang Gung Memorial Hospital at Kaohsiung ( Site 1203) Kaohsiung Niao Sung Dist Kaohsiung 83301 Taiwan Details
China Medical University Hospital ( Site 1202) Taichung 404332 Taiwan Details
Taipei Veterans General Hospital ( Site 1201) Taipei 11217 Taiwan Details
I.I. Mechnykov Dnipropetrovsk Regional Clinical Hospital ( Site 0959) Dnipro Dnipropetrovska Oblast 49005 Ukraine Details
MI Clinical oncology dispensary of Dnipropetrovsk regional council ( Site 0954) Dnipro Dnipropetrovska Oblast 49055 Ukraine Details
Regional Clinical Center of Urology and Nephrology n.a. V.I. Shapoval ( Site 0952) Kharkiv Kharkivska Oblast 61037 Ukraine Details
MNPE Regional Center of Oncology ( Site 0955) Kharkiv Kharkivska Oblast 61070 Ukraine Details
Municipal Non-profit Enterprise of Kharkiv Regional Council RCSDRPP ( Site 0965) Kharkiv Kharkivska Oblast 61166 Ukraine Details
Lviv Oncology Regional Treatment and Diagnostic Center ( Site 0960) Lviv Lvivska Oblast 79031 Ukraine Details
Zhytomyr Regional Oncology Center ( Site 0961) Zhytomyr Zhytomyrska Oblast 10002 Ukraine Details
Torbay Hospital ( Site 1804) Torquay Devon TQ2 7AA United Kingdom Details
St Bartholomew's Hospital-Centre for Experimental Cancer Medicine ( Site 1801) London London, City Of EC1A 7BE United Kingdom Details
Imperial College Healthcare NHS Foundation Trust - St Mary's Hospital ( Site 1802) London London, City Of W2 1NY United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field