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NCT ID | NCT04923893 |
Title | A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5) |
Acronym | CARTITUDE-5 |
Recruitment | Active, not recruiting |
Gender | both |
Phase | Phase III |
Variant Requirements | No |
Sponsors | Janssen Research & Development, LLC |
Indications | |
Therapies | |
Age Groups: | senior | adult |
Covered Countries | USA | SWE | POL | NOR | NLD | ISR | IRL | HUN | GRC | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CHE | CAN | BRA | BEL | AUT | AUS | ARG |
Facility | Status | City | State | Zip | Country | Details |
---|---|---|---|---|---|---|
UCSF | San Francisco | California | 94143 | United States | Details | |
Yale Cancer Center | New Haven | Connecticut | 06510 | United States | Details | |
University of Miami Health System | Miami | Florida | 33136 | United States | Details | |
AdventHealth Cancer Institute | Orlando | Florida | 32832 | United States | Details | |
University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | United States | Details | |
University of Kentucky | Lexington | Kentucky | 40536-0293 | United States | Details | |
Norton Cancer Institute | Louisville | Kentucky | 40207 | United States | Details | |
University Of Maryland Medical Center | Baltimore | Maryland | 21201-1595 | United States | Details | |
Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | United States | Details | |
Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | United States | Details | |
Henry Ford Cancer Institute | Detroit | Michigan | 48202-2608 | United States | Details | |
Columbia University Medical Center | New York | New York | 10032 | United States | Details | |
Memorial Sloan-Kettering Cancer Center | New York | New York | 10065 | United States | Details | |
New York Presbyterian-Weill Cornell Medical College | New York | New York | 10065 | United States | Details | |
Levine Cancer Institute | Charlotte | North Carolina | 28204 | United States | Details | |
Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | United States | Details | |
University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | United States | Details | |
University of Virginia | Charlottesville | Virginia | 22903 | United States | Details | |
Medical College Of Wisconsin | Milwaukee | Wisconsin | 53226 | United States | Details | |
Hospital Aleman | Buenos Aires | C1118AAT | Argentina | Details | ||
Hospital Italiano de Buenos Aires | Buenos Aires | C1199ABD | Argentina | Details | ||
Hospital Privado Centro Medico de Cordoba | Cordoba | X5016KEH | Argentina | Details | ||
Royal Prince Alfred Hospital | Camperdown | 2050 | Australia | Details | ||
St Vincents Hospital Melbourne | Fitzroy | 3065 | Australia | Details | ||
Austin Health | Heidelberg | 3084 | Australia | Details | ||
Royal Brisbane and Womens Hospital | Herston | 4029 | Australia | Details | ||
Alfred Health | Melbourne | 3004 | Australia | Details | ||
Peter MacCallum Cancer Centre | Melbourne | 8006 | Australia | Details | ||
Fiona Stanley Hospital | Murdoch | 6150 | Australia | Details | ||
Calvary Mater Newcastle Hospital | Waratah | 2298 | Australia | Details | ||
Western Sydney Local Health District | Westmead | 2145 | Australia | Details | ||
Medizinische Universität Graz, LKH-Univ.Klinikum Graz, Klinische Abteilung für Hämatologie | Graz | 8036 | Austria | Details | ||
Krankenhaus der Elisabethinen Linz | Linz | 4020 | Austria | Details | ||
LKH - Universitätsklinikum der PMU Salzburg | Salzburg | 5020 | Austria | Details | ||
Medical University of Vienna Universitatsklinik fur Innere Medizin I | Vienna | 1090 | Austria | Details | ||
Universitair Ziekenhuis - Antwerpen | Antwerp | 2650 | Belgium | Details | ||
AZ St.-Jan Brugge-Oostende AV | Brugge | 8000 | Belgium | Details | ||
UZ Gent | Gent | 9000 | Belgium | Details | ||
UZ Leuven | Leuven | 3000 | Belgium | Details | ||
Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman | Liege | B-4000 | Belgium | Details | ||
Hospital Sao Rafael | Salvador | 41253-190 | Brazil | Details | ||
Fundacao Antonio Prudente A C Camargo Cancer Center | Sao Paulo | 01509 900 | Brazil | Details | ||
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein | Sao Paulo | 05652 900 | Brazil | Details | ||
Arthur J. E. Child Comprehensive Cancer Centre | Calgary | Alberta | T2N 5G2 | Canada | Details | |
Vancouver General Hospital | Vancouver | British Columbia | V5Z 1M9 | Canada | Details | |
Juravinski Cancer Centre | Hamilton | Ontario | L8V5C2 | Canada | Details | |
Princess Margaret Cancer Centre University Health Network | Toronto | Ontario | M5G2M9 | Canada | Details | |
Hopital Maisonneuve Rosemont | Montreal | Quebec | H1T 2M4 | Canada | Details | |
Fakultni nemocnice Brno | Brno | 625 00 | Czechia | Details | ||
Fakultni nemocnice Hradec Kralove | Hradec Kralove | 500 05 | Czechia | Details | ||
Fakultni Nemocnice Ostrava | Ostrava - Poruba | 708 52 | Czechia | Details | ||
Vseobecna fakultni nemocnice v Praze | Praha 2 | 128 08 | Czechia | Details | ||
Aarhus University Hospital | Aarhus C | 8000 | Denmark | Details | ||
Rigshospitalet | Copenhagen | 2100 | Denmark | Details | ||
Odense Universitetshospital | Odense C | 5000 | Denmark | Details | ||
Helsinki University Hospital | Helsinki | 00029 HUS | Finland | Details | ||
Oulu University Hospital | Oulu | 90220 | Finland | Details | ||
Turku University Hospital | Turku | 20520 | Finland | Details | ||
Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez | Lille Cedex | 59000 | France | Details | ||
C.H.U. Hotel Dieu - France | Nantes | 44093 | France | Details | ||
Hopital Saint Louis | Paris cedex 10 | 75475 | France | Details | ||
CHU Poitiers - Hopital la Miletrie | Poitiers | 86021 | France | Details | ||
Institut Universitaire du cancer de Toulouse-Oncopole | Toulouse cedex 9 | 31059 | France | Details | ||
Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin | Berlin | 12203 | Germany | Details | ||
Universitaetsklinikum Carl Gustav Carus TU Dresden | Dresden | 01307 | Germany | Details | ||
Universitatsklinikum Freiburg | Freiburg | 79106 | Germany | Details | ||
Universitaetsklinikum Hamburg Eppendorf | Hamburg | 20246 | Germany | Details | ||
Universitaetsklinikum Heidelberg | Heidelberg | 69120 | Germany | Details | ||
Universitaetsklinikum Leipzig | Leipzig | 04103 | Germany | Details | ||
Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Mainz | 55131 | Germany | Details | ||
Klinikum Großhadern der Ludwig-Maximilians-Universität | München | 81377 | Germany | Details | ||
Universitaetsklinikum Regensburg | Regensburg | 93053 | Germany | Details | ||
Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany | Tubingen | 72076 | Germany | Details | ||
Universitatsklinikum Wurzburg | Wuerzburg | 97080 | Germany | Details | ||
Alexandra General Hospital of Athens | Athens | 11528 | Greece | Details | ||
Attikon University General Hospital of Attica | Athens | 12462 | Greece | Details | ||
G.Papanikolaou | Thessaloniki | 57010 | Greece | Details | ||
Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely | Budapest | 1097 | Hungary | Details | ||
Debreceni Egyetem Klinikai Kozpont | Debrecen | 4032 | Hungary | Details | ||
St James Hospital | Dublin | D08 NHY1 | Ireland | Details | ||
Hadassah University Hospita Ein Kerem | Jerusalem | P.O.B. 12000 | Israel | Details | ||
Sheba Medical Center Tel Hashomer | Ramat Gan | 52621 | Israel | Details | ||
Tel Aviv Sourasky Medical Center | Tel Aviv | 64239 | Israel | Details | ||
Juntendo University Hospital | Bunkyo Ku | 113 8431 | Japan | Details | ||
Kyushu University Hospital | Fukuoka | 812 8582 | Japan | Details | ||
Hyogo Medical University Hospital | Hyôgo | 663-8501 | Japan | Details | ||
Kanazawa University Hospital | Kanazawa | 920-8641 | Japan | Details | ||
University Hospital Kyoto Prefectural University of Medicine | Kyoto | 602-8566 | Japan | Details | ||
Nagoya City University Hospital | Nagoya | 467 8602 | Japan | Details | ||
Okayama University Hospital | Okayama | 700-8558 | Japan | Details | ||
Hokkaido University Hospital | Sapporo | 060-8648 | Japan | Details | ||
Tohoku University Hospital | Sendai | 980 8574 | Japan | Details | ||
Japanese Red Cross Medical Center | Shibuya | 150-8935 | Japan | Details | ||
Chonnam National University Hwasun Hospital | Jeollanam-do | 58128 | Korea, Republic of | Details | ||
Seoul National University Hospital | Seoul | 03080 | Korea, Republic of | Details | ||
Severance Hospital Yonsei University Health System | Seoul | 03722 | Korea, Republic of | Details | ||
Asan Medical Center | Seoul | 05505 | Korea, Republic of | Details | ||
Samsung Medical Center | Seoul | 06351 | Korea, Republic of | Details | ||
The Catholic University of Korea Seoul St Marys Hospital | Seoul | 06591 | Korea, Republic of | Details | ||
VU Medisch Centrum | Amsterdam | 1081 HV | Netherlands | Details | ||
University Medical Center Groningen | Groningen | 9713 GZ | Netherlands | Details | ||
UMC Radboud | Nijmegen | 6500 HB | Netherlands | Details | ||
Erasmus MC | Rotterdam | 3075 EA | Netherlands | Details | ||
Oslo universitetssykehus HF, Rikshospitalet | Oslo | 0372 | Norway | Details | ||
Uniwersyteckie Centrum Kliniczne | Gdansk | 80-214 | Poland | Details | ||
Narodowy Instytut Onkologii im.Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz. w Gliwicach | Gliwice | 44102 | Poland | Details | ||
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli | Lublin | 20-090 | Poland | Details | ||
Uniwersytecki Szpital Kliniczny w Poznaniu | Poznan | 60-569 | Poland | Details | ||
Instytut Hematologii i Transfuzjologii | Warszawa | 02-776 | Poland | Details | ||
Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu | Wroclaw | 50-367 | Poland | Details | ||
Instituto Portugues de Oncologia | Lisboa | 1099-023 | Portugal | Details | ||
Instituto Portugues de Oncologia | Porto | 4200072 | Portugal | Details | ||
Hosp. de La Santa Creu I Sant Pau | Barcelona | 08025 | Spain | Details | ||
Hosp Univ Vall D Hebron | Barcelona | 8035 | Spain | Details | ||
Instituto Catalan Deoncologia Hospital Duran I Reynals | L'Hospitalet de Llobregat | 08908 | Spain | Details | ||
Hosp. Gral. Univ. Gregorio Maranon | Madrid | 28007 | Spain | Details | ||
Hosp. Univ. 12 de Octubre | Madrid | 28041 | Spain | Details | ||
Hosp. Univ. Virgen de La Arrixaca | Murcia | 30120 | Spain | Details | ||
Clinica Univ. de Navarra | Pamplona | 31008 | Spain | Details | ||
Hosp Clinico Univ de Salamanca | Salamanca | 37007 | Spain | Details | ||
Hosp. Univ. Marques de Valdecilla | Santander | 39008 | Spain | Details | ||
Hosp. Virgen Del Rocio | Sevilla | 41013 | Spain | Details | ||
Hosp. Univ. I Politecni La Fe | Valencia | 46026 | Spain | Details | ||
Sahlgrenska University Hospital | Goteborg | 413 45 | Sweden | Details | ||
Universitetssjukhuset | Linköping | 58185 | Sweden | Details | ||
Skane University Hospital | Lund | 221 85 | Sweden | Details | ||
Universitatsspital Basel | Basel | 4031 | Switzerland | Details | ||
INSELSPITAL Universitatsspital Bern | Bern | 3010 | Switzerland | Details | ||
Kantonsspital St Gallen | St. Gallen | 9007 | Switzerland | Details | ||
University Hospitals Birmingham NHS Trust, | Birmingham | B15 2TH | United Kingdom | Details | ||
Bristol Royal Infirmary | Bristol | BS2 8BJ | United Kingdom | Details | ||
Leeds Teaching Hospitals NHS Trust | Leeds, | LS9 7TF | United Kingdom | Details | ||
University College Hospital | London | NW1 2BU | United Kingdom | Details | ||
Kings College Hospital | London | SE5 9RS | United Kingdom | Details | ||
Manchester Royal Infirmary | Manchester | M13 9WL | United Kingdom | Details | ||
The Royal Marsden NHS Trust Sutton | Surrey | SM2 5PT | United Kingdom | Details |