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NCT ID NCT04923893
Title A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5)
Acronym CARTITUDE-5
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Janssen Research & Development, LLC
Indications
Therapies
Age Groups: senior | adult
Covered Countries USA | SWE | POL | NOR | NLD | ISR | IRL | HUN | GRC | GBR | FRA | FIN | ESP | DNK | DEU | CZE | CHE | CAN | BRA | BEL | AUT | AUS | ARG

Facility Status City State Zip Country Details
UCSF San Francisco California 94143 United States Details
Yale Cancer Center New Haven Connecticut 06510 United States Details
University of Miami Health System Miami Florida 33136 United States Details
AdventHealth Cancer Institute Orlando Florida 32832 United States Details
University of Iowa Hospitals and Clinics Iowa City Iowa 52242 United States Details
University of Kentucky Lexington Kentucky 40536-0293 United States Details
Norton Cancer Institute Louisville Kentucky 40207 United States Details
University Of Maryland Medical Center Baltimore Maryland 21201-1595 United States Details
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 United States Details
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 United States Details
Henry Ford Cancer Institute Detroit Michigan 48202-2608 United States Details
Columbia University Medical Center New York New York 10032 United States Details
Memorial Sloan-Kettering Cancer Center New York New York 10065 United States Details
New York Presbyterian-Weill Cornell Medical College New York New York 10065 United States Details
Levine Cancer Institute Charlotte North Carolina 28204 United States Details
Thomas Jefferson University Philadelphia Pennsylvania 19107 United States Details
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15232 United States Details
University of Virginia Charlottesville Virginia 22903 United States Details
Medical College Of Wisconsin Milwaukee Wisconsin 53226 United States Details
Hospital Aleman Buenos Aires C1118AAT Argentina Details
Hospital Italiano de Buenos Aires Buenos Aires C1199ABD Argentina Details
Hospital Privado Centro Medico de Cordoba Cordoba X5016KEH Argentina Details
Royal Prince Alfred Hospital Camperdown 2050 Australia Details
St Vincents Hospital Melbourne Fitzroy 3065 Australia Details
Austin Health Heidelberg 3084 Australia Details
Royal Brisbane and Womens Hospital Herston 4029 Australia Details
Alfred Health Melbourne 3004 Australia Details
Peter MacCallum Cancer Centre Melbourne 8006 Australia Details
Fiona Stanley Hospital Murdoch 6150 Australia Details
Calvary Mater Newcastle Hospital Waratah 2298 Australia Details
Western Sydney Local Health District Westmead 2145 Australia Details
Medizinische Universität Graz, LKH-Univ.Klinikum Graz, Klinische Abteilung für Hämatologie Graz 8036 Austria Details
Krankenhaus der Elisabethinen Linz Linz 4020 Austria Details
LKH - Universitätsklinikum der PMU Salzburg Salzburg 5020 Austria Details
Medical University of Vienna Universitatsklinik fur Innere Medizin I Vienna 1090 Austria Details
Universitair Ziekenhuis - Antwerpen Antwerp 2650 Belgium Details
AZ St.-Jan Brugge-Oostende AV Brugge 8000 Belgium Details
UZ Gent Gent 9000 Belgium Details
UZ Leuven Leuven 3000 Belgium Details
Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman Liege B-4000 Belgium Details
Hospital Sao Rafael Salvador 41253-190 Brazil Details
Fundacao Antonio Prudente A C Camargo Cancer Center Sao Paulo 01509 900 Brazil Details
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein Sao Paulo 05652 900 Brazil Details
Arthur J. E. Child Comprehensive Cancer Centre Calgary Alberta T2N 5G2 Canada Details
Vancouver General Hospital Vancouver British Columbia V5Z 1M9 Canada Details
Juravinski Cancer Centre Hamilton Ontario L8V5C2 Canada Details
Princess Margaret Cancer Centre University Health Network Toronto Ontario M5G2M9 Canada Details
Hopital Maisonneuve Rosemont Montreal Quebec H1T 2M4 Canada Details
Fakultni nemocnice Brno Brno 625 00 Czechia Details
Fakultni nemocnice Hradec Kralove Hradec Kralove 500 05 Czechia Details
Fakultni Nemocnice Ostrava Ostrava - Poruba 708 52 Czechia Details
Vseobecna fakultni nemocnice v Praze Praha 2 128 08 Czechia Details
Aarhus University Hospital Aarhus C 8000 Denmark Details
Rigshospitalet Copenhagen 2100 Denmark Details
Odense Universitetshospital Odense C 5000 Denmark Details
Helsinki University Hospital Helsinki 00029 HUS Finland Details
Oulu University Hospital Oulu 90220 Finland Details
Turku University Hospital Turku 20520 Finland Details
Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez Lille Cedex 59000 France Details
C.H.U. Hotel Dieu - France Nantes 44093 France Details
Hopital Saint Louis Paris cedex 10 75475 France Details
CHU Poitiers - Hopital la Miletrie Poitiers 86021 France Details
Institut Universitaire du cancer de Toulouse-Oncopole Toulouse cedex 9 31059 France Details
Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin Berlin 12203 Germany Details
Universitaetsklinikum Carl Gustav Carus TU Dresden Dresden 01307 Germany Details
Universitatsklinikum Freiburg Freiburg 79106 Germany Details
Universitaetsklinikum Hamburg Eppendorf Hamburg 20246 Germany Details
Universitaetsklinikum Heidelberg Heidelberg 69120 Germany Details
Universitaetsklinikum Leipzig Leipzig 04103 Germany Details
Universitätsmedizin der Johannes Gutenberg-Universität Mainz Mainz 55131 Germany Details
Klinikum Großhadern der Ludwig-Maximilians-Universität München 81377 Germany Details
Universitaetsklinikum Regensburg Regensburg 93053 Germany Details
Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany Tubingen 72076 Germany Details
Universitatsklinikum Wurzburg Wuerzburg 97080 Germany Details
Alexandra General Hospital of Athens Athens 11528 Greece Details
Attikon University General Hospital of Attica Athens 12462 Greece Details
G.Papanikolaou Thessaloniki 57010 Greece Details
Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely Budapest 1097 Hungary Details
Debreceni Egyetem Klinikai Kozpont Debrecen 4032 Hungary Details
St James Hospital Dublin D08 NHY1 Ireland Details
Hadassah University Hospita Ein Kerem Jerusalem P.O.B. 12000 Israel Details
Sheba Medical Center Tel Hashomer Ramat Gan 52621 Israel Details
Tel Aviv Sourasky Medical Center Tel Aviv 64239 Israel Details
Juntendo University Hospital Bunkyo Ku 113 8431 Japan Details
Kyushu University Hospital Fukuoka 812 8582 Japan Details
Hyogo Medical University Hospital Hyôgo 663-8501 Japan Details
Kanazawa University Hospital Kanazawa 920-8641 Japan Details
University Hospital Kyoto Prefectural University of Medicine Kyoto 602-8566 Japan Details
Nagoya City University Hospital Nagoya 467 8602 Japan Details
Okayama University Hospital Okayama 700-8558 Japan Details
Hokkaido University Hospital Sapporo 060-8648 Japan Details
Tohoku University Hospital Sendai 980 8574 Japan Details
Japanese Red Cross Medical Center Shibuya 150-8935 Japan Details
Chonnam National University Hwasun Hospital Jeollanam-do 58128 Korea, Republic of Details
Seoul National University Hospital Seoul 03080 Korea, Republic of Details
Severance Hospital Yonsei University Health System Seoul 03722 Korea, Republic of Details
Asan Medical Center Seoul 05505 Korea, Republic of Details
Samsung Medical Center Seoul 06351 Korea, Republic of Details
The Catholic University of Korea Seoul St Marys Hospital Seoul 06591 Korea, Republic of Details
VU Medisch Centrum Amsterdam 1081 HV Netherlands Details
University Medical Center Groningen Groningen 9713 GZ Netherlands Details
UMC Radboud Nijmegen 6500 HB Netherlands Details
Erasmus MC Rotterdam 3075 EA Netherlands Details
Oslo universitetssykehus HF, Rikshospitalet Oslo 0372 Norway Details
Uniwersyteckie Centrum Kliniczne Gdansk 80-214 Poland Details
Narodowy Instytut Onkologii im.Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz. w Gliwicach Gliwice 44102 Poland Details
Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli Lublin 20-090 Poland Details
Uniwersytecki Szpital Kliniczny w Poznaniu Poznan 60-569 Poland Details
Instytut Hematologii i Transfuzjologii Warszawa 02-776 Poland Details
Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu Wroclaw 50-367 Poland Details
Instituto Portugues de Oncologia Lisboa 1099-023 Portugal Details
Instituto Portugues de Oncologia Porto 4200072 Portugal Details
Hosp. de La Santa Creu I Sant Pau Barcelona 08025 Spain Details
Hosp Univ Vall D Hebron Barcelona 8035 Spain Details
Instituto Catalan Deoncologia Hospital Duran I Reynals L'Hospitalet de Llobregat 08908 Spain Details
Hosp. Gral. Univ. Gregorio Maranon Madrid 28007 Spain Details
Hosp. Univ. 12 de Octubre Madrid 28041 Spain Details
Hosp. Univ. Virgen de La Arrixaca Murcia 30120 Spain Details
Clinica Univ. de Navarra Pamplona 31008 Spain Details
Hosp Clinico Univ de Salamanca Salamanca 37007 Spain Details
Hosp. Univ. Marques de Valdecilla Santander 39008 Spain Details
Hosp. Virgen Del Rocio Sevilla 41013 Spain Details
Hosp. Univ. I Politecni La Fe Valencia 46026 Spain Details
Sahlgrenska University Hospital Goteborg 413 45 Sweden Details
Universitetssjukhuset Linköping 58185 Sweden Details
Skane University Hospital Lund 221 85 Sweden Details
Universitatsspital Basel Basel 4031 Switzerland Details
INSELSPITAL Universitatsspital Bern Bern 3010 Switzerland Details
Kantonsspital St Gallen St. Gallen 9007 Switzerland Details
University Hospitals Birmingham NHS Trust, Birmingham B15 2TH United Kingdom Details
Bristol Royal Infirmary Bristol BS2 8BJ United Kingdom Details
Leeds Teaching Hospitals NHS Trust Leeds, LS9 7TF United Kingdom Details
University College Hospital London NW1 2BU United Kingdom Details
Kings College Hospital London SE5 9RS United Kingdom Details
Manchester Royal Infirmary Manchester M13 9WL United Kingdom Details
The Royal Marsden NHS Trust Sutton Surrey SM2 5PT United Kingdom Details
*Shaded cells indicate that there was no data available from clinicaltrials.gov for the field