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| NCT ID | NCT04987203 |
| Title | Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AVEO Pharmaceuticals, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | ITA | GBR | FRA | ESP | DEU | CZE | CAN | BRA | BEL | AUS | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | United States | Details | |
| Chao Family Comprehensive Cancer Center, UC Irvine | Irvine | California | 92868 | United States | Details | |
| University of California San Diego | La Jolla | California | 92037 | United States | Details | |
| Leland Stanford Junior University | Redwood City | California | 94063 | United States | Details | |
| Kaiser Permanente Riverside Medical Center | Riverside | California | 92505 | United States | Details | |
| US Oncology - Rocky Mountain Cancer Centers - Midtown | Denver | Colorado | 80218-1237 | United States | Details | |
| Florida Cancer Specialists & Res Inst | Fort Myers | Florida | 33901 | United States | Details | |
| Florida Cancer Specialists & Research Institute (FCS) - Tampa Cancer Center Location | Saint Petersburg | Florida | 33705 | United States | Details | |
| The University of Kansas Cancer Center | Westwood | Kansas | 66205-2005 | United States | Details | |
| University of Kentucky UK Markey Cancer Center | Lexington | Kentucky | 40536 | United States | Details | |
| Tulane Cancer Center Clinic - Oncology | New Orleans | Louisiana | 70112 | United States | Details | |
| University of Maryland Medical Center-Greenebaum Cancer Ctr | Baltimore | Maryland | 21201 | United States | Details | |
| John Hopkins Medicine - Hematology/oncology | Baltimore | Maryland | 21287 | United States | Details | |
| Maryland Oncology Hematology | Clinton | Maryland | 20735 | United States | Details | |
| Dana-Farber Cancer Institute - Medicine | Boston | Massachusetts | 02215 | United States | Details | |
| Henry Ford Hospital | Detroit | Michigan | 48202 | United States | Details | |
| St. Vincent Frontier Cancer Center | Billings | Montana | 59102-6746 | United States | Details | |
| Oncology Hematology West PC dba Nebraska Cancer Specialists | Omaha | Nebraska | 68130 | United States | Details | |
| Memorial Sloan Kettering Cancer Center - Monmouth - Oncology | Middletown | New Jersey | 07748-3052 | United States | Details | |
| University of New Mexico - Comprehensive Cancer Center | Albuquerque | New Mexico | 87131-0001 | United States | Details | |
| Roswell - Roswell Park Cancer Institute - Medical Oncology | Buffalo | New York | 14263 | United States | Details | |
| Memorial Sloan Kettering Cancer Center - Westchester | Harrison | New York | 10604 | United States | Details | |
| Memorial Sloan Kettering Cancer Center (MSKCC) - Memorial Hospital | New York | New York | 10065 | United States | Details | |
| Memorial Sloan Kettering Cancer Center - Nassau | Uniondale | New York | 11553 | United States | Details | |
| Cleveland Clinic | Cleveland | Ohio | 44195-0001 | United States | Details | |
| Lehigh Valley Physician Group | Allentown | Pennsylvania | 18103-6218 | United States | Details | |
| Allegheny General Hospital (AGH) | Pittsburgh | Pennsylvania | 15212-4756 | United States | Details | |
| UH Cleveland Medical Center | Columbia | South Carolina | 29210 | United States | Details | |
| Chattanooga Oncology and Hematology Associates | Chattanooga | Tennessee | 37404 | United States | Details | |
| Tennessee Oncology, PLLC | Nashville | Tennessee | 37203 | United States | Details | |
| Vanderbilt-Ingram Cancer Center | Nashville | Tennessee | 37232 | United States | Details | |
| Texas Oncology - Central Austin Cancer Center | Austin | Texas | 78731 | United States | Details | |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | United States | Details | |
| US Oncology Texas Oncology (CCC of South Texas) - San Antonio Medical Center | San Antonio | Texas | 78240 | United States | Details | |
| University Of Washington - Medical Center | Seattle | Washington | 98109 | United States | Details | |
| Northwest Medical Specialties PLLC | Tacoma | Washington | 98405-5016 | United States | Details | |
| Centro Oncológico Korben | Buenos Aires | Ciudad Autónoma De Buenos Aire | C1280AEB | Argentina | Details | |
| Clínica Viedma | Viedma | Río Negro | R8500JYJ | Argentina | Details | |
| Centro Oncologico de Rosario | Rosario | Santa Fe | S2000KZE | Argentina | Details | |
| Centro para la Atención Integral del paciente Oncológico | San Miguel de Tucumán | Tucumán | T4000GTB | Argentina | Details | |
| Liverpool Hospital Cancer Therapy Centre | Liverpool | New South Wales | 2170 | Australia | Details | |
| Mater Misericordiae Limited | Brisbane | Queensland | 4101 | Australia | Details | |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia | Details | |
| Sunshine Hospital | Geelong | Victoria | 3220 | Australia | Details | |
| ZNA Jan Palfijn | Merksen | Antwerpen | 2170 | Belgium | Details | |
| Institut Jules Bordet - Oncologie Médicale | Anderlecht | Brussels Capital Region | 1070 | Belgium | Details | |
| Jessa Ziekenhuis - Campus Virga Jesse - Medische Oncologie | Hasselt | Limburg | 3500 | Belgium | Details | |
| UZ Gent - Medische Oncologie | Gent | Oost-Vlaanderen | 9000 | Belgium | Details | |
| CHU Brugmann - Victor Horta | Bruxelles | 1020 | Belgium | Details | ||
| AZ Groeninge - Campus Kennedylaan | Kortrijk | 8500 | Belgium | Details | ||
| Centro Gaucho Integrado de Onc | Porto Alegre | Rio Grande Do Sul | 90110-270 | Brazil | Details | |
| Clinica de Neoplasias Litoral | Itajai | Santa Catarina | 88301-220 | Brazil | Details | |
| Universidade Estadual de Campi | Campinas | São Paulo | 13083-970 | Brazil | Details | |
| Hospital Nossa Senhora da Conc | Porto Alegre | 90610-000 | Brazil | Details | ||
| Pontificia Universidade | Porto Alegre | 90610-000 | Brazil | Details | ||
| Instituto Brasileiro de Controle do Cancer - ibcc | São Paulo | 03102-002 | Brazil | Details | ||
| Tom Baker Cancer Centre | Calgary | Alberta | T2N 4N2 | Canada | Details | |
| BC Cancer - Vancouver Centre | Vancouver | British Columbia | V5Z 4E6 | Canada | Details | |
| Sunnybrook Research Institute, sunnybrook Health Sciences Ct | Toronto | Ontario | M4N 3M5 | Canada | Details | |
| University Health Network - Princess Margaret Cancer Centre | Toronto | Ontario | M5G 2M9 | Canada | Details | |
| Meditek Ltda. | Santiago de Chile | Región Metropolitana De Santiago | 8420383 | Chile | Details | |
| Centro de Estudios Clinicos In | Santiago | Región Metropolitana De Santia | 8420383 | Chile | Details | |
| Centro de Estudios Clínicos SAGA SpA | Santiago | Región Metropolitana De Santia | Chile | Details | ||
| ACEREY Centro de Investigación Clínica Oncológica | Viña del mar | Valparaíso | 2520612 | Chile | Details | |
| FN Hradec Kralove | Hradec Kralove | 500 05 | Czechia | Details | ||
| FN Kralovske Vinohrady | Praha 10 | 100 34 | Czechia | Details | ||
| Fakultni Thomayerova nemocnice | Praha 4 | 140 59 | Czechia | Details | ||
| Institut de cancérologie de Strasbourg Europe - ICANS | Strasbourg | Alsace | 67200 | France | Details | |
| Institut Paoli Calmettes - Hôpital de jour | Marseille | Bouches-du-Rhône | 13273 | France | Details | |
| Hopital Saint-Andre - Service d'Oncologie Medicale | Bordeaux | Gironde | 33075 | France | Details | |
| Hopital Foch | Suresnes | Hauts-de-Seine | 92151 | France | Details | |
| CHU Michallon - Hopital Nord - Cancérologie Et Hématologie | Grenoble | Isère | 38043 | France | Details | |
| Hôpital privé Le Bois | Lille | Nord | 59000 | France | Details | |
| Centre Hospitalier de Poitiers | Poitiers | Poitou-Charentes | 86021 | France | Details | |
| Hospices Civils de Lyon (HCL) - Centre Hospitalier Lyon-Sud | Pierre-Bénite | Rhône-Alpes | 69495 | France | Details | |
| Centre Leon Berard - departement d'oncologie medicale | Lyon | Rhône | 69373 | France | Details | |
| Clinique Victor Hugo - Hematologie | Le Mans | Sarthe | 72000 | France | Details | |
| CHD Vendee La Roche sur Yon - Gastro-Entérologie | La Roche-sur-Yon | 85925 | France | Details | ||
| Centre de Lutte Contre le Cancer (CLCC) | Nice | 06189 | France | Details | ||
| ICO - Site Rene Gauducheau - Oncologie Medicale | St Herblain | 44805 | France | Details | ||
| Hopital Trousseau - medical oncology | Tours | 37044 | France | Details | ||
| Institut de Cancérologie de Lorraine | Vandœuvre-lès-Nancy | 54511 | France | Details | ||
| Centre de Lutte Contre le Cancer (CLCC) - Gustave Roussy (Institut de Cancerologie Gustave-Roussy) | Villejuif | Île-de-France | 94805 | France | Details | |
| Universitätsklinikum Heidelberg | Heidelberg | Baden-Württemberg | 69120 | Germany | Details | |
| Medizinische Hochschule Hannover | Hannover | Niedersachsen | 30625 | Germany | Details | |
| P.O. Ss. Annunziata | Chieti Scalo | Chieti | 66013 | Italy | Details | |
| IRST | Meldola (Fc) | Forli | 47014 | Italy | Details | |
| Ospedale S.Donato, AUSL 8 di Arezzo | Arezzo | 52100 | Italy | Details | ||
| Azienda Mater Domini | Catanzaro | 88100 | Italy | Details | ||
| PO di Cremona, ASST di Cremona - Oncologia medica | Cremona | Italy | Details | |||
| AOUC Azienda Ospedaliero-Universitaria Careggi | Firenze | 50134 | Italy | Details | ||
| European Institute of Oncology | Milano | 20141 | Italy | Details | ||
| IRCCS Fondazione "Giovanni Pas | Napoli | 80131 | Italy | Details | ||
| IRCCS Policlinico San Matteo | Pavia | 27100 | Italy | Details | ||
| Fondazione Policlinico Universitario Agostino Gemelli | Roma | '00168 | Italy | Details | ||
| AO S.Camillo-Forlanini | Roma | 00152 | Italy | Details | ||
| Azienda Ospedaliera Santa Maria di Terni | Terni | 05100 | Italy | Details | ||
| Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán | Tlalpan | 14080 | Mexico | Details | ||
| Szpital Specjalistyczny im. L. Rydygiera w Krakowie | Kraków | Malopolskie | 31-826 | Poland | Details | |
| Europejskie Centrum Zdrowia Otwock, Szpital im. F. Chopina | Otwock | Mazowieckie | 05-400 | Poland | Details | |
| Szpital Specjalist. w Brzozowie,Podkarpacki Ośrodek Onkologi | Brzozow | Podkarpackie | 36-200 | Poland | Details | |
| Nzoz Mrukmed Lekarz Beata Madej-Mruk I Partner Sp. P. | Rzeszow | Podkarpackie | 35-021 | Poland | Details | |
| COPERNICUS Podmiot Leczn. Sp z o.o.,Wojew. Centrum Onkologii | Gdańsk | Pomorskie | 80-219 | Poland | Details | |
| Szpital Kliniczny Przemienienia Panskiego UM w Poznaniu | Poznan | Wielkopolskie | 60-569 | Poland | Details | |
| Wojewodzki Szpital Specjalistyczny | Biala Podlaska | 21-500 | Poland | Details | ||
| Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych | Warszawa | 02-507 | Poland | Details | ||
| Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie - Państwowy Instytut Badawczy | Warszawa | 02-781 | Poland | Details | ||
| H. Prof. Doutor Fernando Fonseca | Amadora | Lisboa | 2720-276 | Portugal | Details | |
| Hospital Particular do Algarve - Gambelas-Faro | Faro | 8005-226 | Portugal | Details | ||
| H. de Santa Maria. Centro Hospitalar Lisboa Norte - Oncologia | Lisboa | 1649-035 | Portugal | Details | ||
| H. Santo Antonio. Centro Hospitalar do Porto | Porto | 4099-001 | Portugal | Details | ||
| Instituto Português Oncologia Francisco Gentil do Porto | Porto | 4200-072 | Portugal | Details | ||
| H.G.U. de Elche | Elche | Alicante | 03203 | Spain | Details | |
| Hospital Universitario Son Espases | Palma de Mallorca | Baleares | 07010 | Spain | Details | |
| Hospital Universitari Parc Tau | Sabadell | Barcelona | 8208 | Spain | Details | |
| Hospital Universitario Y Politécnico La Fe | Valencia | Valenciana, Comunidad | 46026 | Spain | Details | |
| Hospital de La Santa Creu i Sant Pau | Barcelona | 08025 | Spain | Details | ||
| Hospital Universitario Vall d' | Barcelona | 08035 | Spain | Details | ||
| Institut Catalá d´Oncología (I.C.O.) | Barcelona | 08908 | Spain | Details | ||
| Hospital Del Mar | Barcelona | 8003 | Spain | Details | ||
| ICO-Hospital Universitari de G | Girona | 17007 | Spain | Details | ||
| Hospital Universitario Ramón y Cajal | Madrid | 28034 | Spain | Details | ||
| Hospital Clínico San Carlos | Madrid | 28040 | Spain | Details | ||
| Hospital U. 12 Octubre | Madrid | 28041 | Spain | Details | ||
| Hospital Universitario La Paz | Madrid | 28046 | Spain | Details | ||
| C.H.U. de Orense | Orense | 32005 | Spain | Details | ||
| Hospital Universitario Virgen | Sevilla | 41009 | Spain | Details | ||
| Fundación Instituto Valenciano | Valencia | 46009 | Spain | Details | ||
| Addenbrooke's Hospital - Oncology | Cambridge | Cambridgeshire | CB2 0QQ | United Kingdom | Details | |
| Mount Vernon Cancer Centre | Northwood | England | HA6 2JW | United Kingdom | Details | |
| Royal Blackburn Hospital - Oncology | Preston | Lancashire | PR2 9HT | United Kingdom | Details | |
| Imperial College Healthcare NHS Trust - Hammersmith Hospital | London | London, City Of | W6 8RF | United Kingdom | Details | |
| Royal Marsden - Sutton | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Royal Marsden Hospital | Sutton | Surrey | SM2 5PT | United Kingdom | Details | |
| Royal Derby Hospital | Derby | DE22 3NE | United Kingdom | Details | ||
| Leeds Teaching Hospitals NHS Trust | Leeds | LS9 7TF | United Kingdom | Details | ||
| The Christie NHS Foundation Trust - Medical Oncology | Manchester | M20 4BX | United Kingdom | Details | ||
| New Cross Hospital | Wolverhampton | WV10 0QP | United Kingdom | Details |