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| NCT ID | NCT05458297 |
| Title | A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination With Nemtabrutinib (MK-1026) in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | No |
| Sponsors | Merck Sharp & Dohme LLC |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | SWE | POL | ITA | ISR | IRL | GBR | EST | ESP | DEU | CZE | CAN | BRA |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alaska Oncology and Hematology ( Site 0037) | RECRUITING | Anchorage | Alaska | 99508 | United States | Details |
| Banner MD Anderson Cancer Center ( Site 0040) | RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| Banner MD Anderson Cancer Center - University Medical Center Phoenix-Medical Oncology ( Site 0036) | RECRUITING | Phoenix | Arizona | 85006 | United States | Details |
| University of Colorado Anschutz Medical Campus-The Center for Cancer and Blood Disorders ( Site 0008 | RECRUITING | Aurora | Colorado | 80045 | United States | Details |
| Cancer Care Specialists of Illinois ( Site 0031) | RECRUITING | Decatur | Illinois | 62526 | United States | Details |
| University of Kansas Medical Center-Division of Hematologic Malignancies and Cellular Therapeutics ( | RECRUITING | Fairway | Kansas | 66205 | United States | Details |
| Norton Women's and Children's Hospital-Norton Cancer Institute - St. Matthews ( Site 0007) | RECRUITING | Saint Matthews | Kentucky | 40207 | United States | Details |
| Greenebaum Comprehensive Cancer Center-Hematology & Multiple Myeloma ( Site 0010) | RECRUITING | Baltimore | Maryland | 21201 | United States | Details |
| Tufts Medical Center ( Site 0024) | RECRUITING | Boston | Massachusetts | 02111 | United States | Details |
| Massachusetts General Hospital ( Site 0018) | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Dana-Farber Cancer Institute-Lymphoma ( Site 0026) | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| University of Michigan ( Site 0009) | RECRUITING | Ann Arbor | Michigan | 48109 | United States | Details |
| Henry Ford Hospital ( Site 0035) | RECRUITING | Detroit | Michigan | 48202 | United States | Details |
| Icahn School of Medicine at Mount Sinai ( Site 0023) | RECRUITING | New York | New York | 10029 | United States | Details |
| Sanford Fargo Medical Center-Roger Maris Cancer Center ( Site 0014) | COMPLETED | Fargo | North Dakota | 58122 | United States | Details |
| The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C | RECRUITING | Columbus | Ohio | 43210 | United States | Details |
| Avera Cancer Institute- Research ( Site 0011) | RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Medical Oncology Associates, PS ( Site 0005) | RECRUITING | Spokane | Washington | 99208 | United States | Details |
| University of Wisconsin Hospitals and Clinics-Carbone Cancer Center ( Site 0030) | RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| MEDICAL COLLEGE OF WISCONSIN ( Site 0021) | RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 1807) | RECRUITING | Natal | Rio Grande Do Norte | 59075-740 | Brazil | Details |
| Instituto Nacional de Câncer - INCA-Divisão de Pesquisa Clínica e Desenvolvimento Tecnológico HC1 ( | RECRUITING | Rio de Janeiro | 20231-050 | Brazil | Details | |
| ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 1808) | RECRUITING | Sao Paulo | 01246-000 | Brazil | Details | |
| Hospital Paulistano-Americas Oncologia ( Site 1805) | RECRUITING | Sao Paulo | 01321-001 | Brazil | Details | |
| BC Cancer Vancouver-Clinical Trials Unit ( Site 0201) | RECRUITING | Vancouver | British Columbia | V5Z 4E6 | Canada | Details |
| The Moncton Hospital-Oncology ( Site 0211) | RECRUITING | Moncton | New Brunswick | E1C 6Z8 | Canada | Details |
| QEII Health Sciences Centre - Victoria General Site ( Site 0213) | RECRUITING | Halifax | Nova Scotia | B3H 2Y9 | Canada | Details |
| Lawson Health Research Institute - London Health Sciences Ce-London Regional Cancer Program ( Site 0 | RECRUITING | London | Ontario | N6A 5W9 | Canada | Details |
| Princess Margaret Cancer Centre-Division of Medical Oncology and Hematology ( Site 0200) | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Jewish General Hospital ( Site 0202) | RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| Allan Blair Cancer Centre-Care Services ( Site 0208) | RECRUITING | Regina | Saskatchewan | S4T 7T1 | Canada | Details |
| IC La Serena Research ( Site 1909) | RECRUITING | La Serena. | Coquimbo | 1720430 | Chile | Details |
| Centro de Estudios Clínicos SAGA-CECSAGA ( Site 1907) | RECRUITING | Santiago | Region M. De Santiago | 7500653 | Chile | Details |
| Clínica Inmunocel ( Site 1910) | RECRUITING | Santiago | Region M. De Santiago | 7580206 | Chile | Details |
| Clínica Alemana de Santiago ( Site 1903) | RECRUITING | Santiago | Region M. De Santiago | 7650568 | Chile | Details |
| Beijing Cancer hospital ( Site 1200) | RECRUITING | Beijing | Beijing | 100142 | China | Details |
| Zhujiang Hospital ( Site 1207) | RECRUITING | Guangzhou | Guangdong | 510280 | China | Details |
| Southern Medical University Nanfang Hospital ( Site 1202) | RECRUITING | Guangzhou | Guangdong | 510515 | China | Details |
| Sun Yat-sen University Cancer Center ( Site 1201) | RECRUITING | Guangzhou | Guangdong | 510700 | China | Details |
| Henan Cancer Hospital-hematology department ( Site 1212) | RECRUITING | Zhengzhou | Henan | 450003 | China | Details |
| Union Hospital Tongji Medical College Huazhong University of Science and Technology ( Site 1210) | RECRUITING | Wuhan | Hubei | 430010 | China | Details |
| Tongji Hospital Tongji Medical,Science & Technology ( Site 1221) | RECRUITING | Wuhan | Hubei | 430030 | China | Details |
| The First Affiliated Hospital of Soochow University-hematology department ( Site 1218) | RECRUITING | Suzhou | Jiangsu | 215006 | China | Details |
| The Affiliated Hospital of Xuzhou Medical College ( Site 1223) | RECRUITING | Xuzhou | Jiangsu | 221000 | China | Details |
| The First Affiliated Hospital of Nanchang University ( Site 1204) | RECRUITING | Nanchang | Jiangxi | 330006 | China | Details |
| Jiangxi Provincial Cancer Hospital ( Site 1213) | RECRUITING | Nanchang | Jiangxi | 330029 | China | Details |
| Jilin Province Tumor Hospital-oncology department ( Site 1220) | RECRUITING | Changchun | Jilin | 132000 | China | Details |
| Fudan University Shanghai Cancer Center ( Site 1208) | RECRUITING | Shanghai | Shanghai | 200032 | China | Details |
| West China Hospital of Sichuan University-Head and Neck Oncology ( Site 1206) | RECRUITING | Cheng Du | Sichuan | 610041 | China | Details |
| The First Affiliated Hospital, Zhejiang University ( Site 1211) | RECRUITING | Hangzhou | Zhejiang | 310003 | China | Details |
| Zhejiang Cancer Hospital ( Site 1214) | RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Fakultní nemocnice Brno Bohunice-Interni hematologicka a onkologicka klinika ( Site 0300) | RECRUITING | Brno | Brno-mesto | 625 00 | Czechia | Details |
| Fakultni nemocnice Ostrava-Klinika Hematoonkologie ( Site 0301) | RECRUITING | Ostrava | Moravskoslezsky Kraj | 708 52 | Czechia | Details |
| Vseobecna fakultni nemocnice v Praze-I. Interní klinika - klinika hematologie ( Site 0302) | RECRUITING | Praha 2 | 128 08 | Czechia | Details | |
| North Estonia Medical Centre Foundation ( Site 0401) | RECRUITING | Tallinn | Harjumaa | 13419 | Estonia | Details |
| Universitaetsklinikum Ulm ( Site 0502) | RECRUITING | Ulm | Baden-Wurttemberg | 89081 | Germany | Details |
| Universitaetsklinikum Koeln ( Site 0506) | RECRUITING | Köln | Nordrhein-Westfalen | 50937 | Germany | Details |
| St. James's Hospital ( Site 0600) | RECRUITING | Dublin | D08 E9P6 | Ireland | Details | |
| Emek Medical Center-Hematology Unit ( Site 0705) | RECRUITING | Afula | 1834111 | Israel | Details | |
| Soroka Medical Center-Hematology Department ( Site 0707) | RECRUITING | Be'er Sheva | 8410101 | Israel | Details | |
| Rambam Health Care Campus-Hematology and Bone Marrow Transplantation ( Site 0706) | RECRUITING | Haifa | 3109601 | Israel | Details | |
| Carmel Hospital ( Site 0709) | RECRUITING | Haifa | 3436212 | Israel | Details | |
| Hadassah Medical Center ( Site 0701) | RECRUITING | Jerusalem | 9112001 | Israel | Details | |
| Galilee Medical Center ( Site 0710) | RECRUITING | Nahariya | 2210001 | Israel | Details | |
| Sheba Medical Center-Hemato Oncology ( Site 0700) | RECRUITING | Ramat Gan | 5265601 | Israel | Details | |
| IRCCS - AOU di Bologna-SSD: Diagnosi e terapie dei linfomi e delle sindromi linfoproliferative cron | RECRUITING | Bologna | Emilia-Romagna | 40138 | Italy | Details |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS -ISTITUTO DI EMATOLOGIA ( Site 0804) | RECRUITING | Roma | Lazio | 00168 | Italy | Details |
| Humanitas-U.O di Oncologia medica ed Ematologia ( Site 0802) | RECRUITING | Rozzano | Milano | 20089 | Italy | Details |
| Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare -Azienda Ospedaliera Nazionale SS. Ant | COMPLETED | Alessandria | 15121 | Italy | Details | |
| National Hospital Organization Nagoya Medical Center ( Site 1108) | RECRUITING | Nagoya | Aichi | 460-0001 | Japan | Details |
| Hokkaido University Hospital ( Site 1104) | RECRUITING | Sapporo | Hokkaido | 060-8648 | Japan | Details |
| Tokai University Hospital- Isehara Campus ( Site 1100) | RECRUITING | Isehara | Kanagawa | 259-1193 | Japan | Details |
| Tohoku University Hospital ( Site 1106) | RECRUITING | Sendai-shi | Miyagi | 980-8574 | Japan | Details |
| Kindai University Hospital- Osakasayama Campus ( Site 1102) | RECRUITING | Osaka-sayama | Osaka | 589-8511 | Japan | Details |
| National Cancer Center Hospital ( Site 1103) | RECRUITING | Chuo-ku | Tokyo | 104-0045 | Japan | Details |
| Japanese Foundation for Cancer Research ( Site 1101) | RECRUITING | Koto | Tokyo | 135-8550 | Japan | Details |
| Kyushu University Hospital ( Site 1105) | RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Okayama University Hospital ( Site 1107) | RECRUITING | Okayama | 700-8558 | Japan | Details | |
| Seoul National University Hospital ( Site 1300) | RECRUITING | Seoul | 03080 | Korea, Republic of | Details | |
| Samsung Medical Center ( Site 1301) | RECRUITING | Seoul | 06351 | Korea, Republic of | Details | |
| Centro Medico Monte Carmelo ( Site 1702) | RECRUITING | Arequipa | Ariqipa | 04001 | Peru | Details |
| INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 1700) | RECRUITING | Lima | 15038 | Peru | Details | |
| Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumat-Oddiał Hematologii Ogólnej ( Site 1008) | COMPLETED | Łódź | Lodzkie | 93-513 | Poland | Details |
| Centrum Onkologii Ziemi Lubelskiej-Oddzial Hematologiczny ( Site 1006) | RECRUITING | Lublin | Lubelskie | 20-090 | Poland | Details |
| Pratia MCM Krakow ( Site 1001) | RECRUITING | Krakow | Malopolskie | 30-727 | Poland | Details |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - P-Klinika Nowotworów Układu Chłonnego ( S | RECRUITING | Warszawa | Mazowieckie | 02-781 | Poland | Details |
| Samodzielny Publiczny Zakład Opieki Zdrowotnej MSWiA w Olsztynie-Oddzial Kliniczny Hematologii ( Sit | RECRUITING | Olsztyn | Warminsko-mazurskie | 10-228 | Poland | Details |
| Champalimaud Foundation ( Site 2002) | RECRUITING | Lisbon | Lisboa | 1400-038 | Portugal | Details |
| Unidade Local de Saude de Braga - Hospital de Braga ( Site 2001) | RECRUITING | Braga | 4710-243 | Portugal | Details | |
| Instituto Português de Oncologia do Porto Francisco Gentil, EPE ( Site 2000) | RECRUITING | Porto | 4200-072 | Portugal | Details | |
| National Cancer Centre Singapore ( Site 1500) | RECRUITING | Singapore | Central Singapore | 168583 | Singapore | Details |
| Instituto Catalan de Oncologia - Hospital Duran i Reynals-Haematology Department ( Site 4003) | COMPLETED | L'Hospitalet Del Llobregat | Barcelona | 08908 | Spain | Details |
| Hospital Universitari Vall d'Hebron ( Site 4004) | RECRUITING | Barcelona | Cataluna | 08035 | Spain | Details |
| MD Anderson Cancer Center ( Site 4006) | RECRUITING | Madrid | Madrid, Comunidad De | 28033 | Spain | Details |
| Clinica Universidad de Navarra ( Site 4005) | RECRUITING | Pamplona | Navarra | 31008 | Spain | Details |
| Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca-Hematology ( S | RECRUITING | Salamanca | 37007 | Spain | Details | |
| Skånes Universitetssjukhus Lund ( Site 5000) | RECRUITING | Lund | Skane Lan | 22185 | Sweden | Details |
| Akademiska sjukhuset-Blod- och tumörsjukdomar ( Site 5002) | RECRUITING | Uppsala | Uppsala Lan | 751 85 | Sweden | Details |
| Sahlgrenska Universitetssjukhuset ( Site 5003) | RECRUITING | Gothenburg | Vastra Gotalands Lan | 413 45 | Sweden | Details |
| Mega Medipol-Hematology ( Site 6009) | RECRUITING | Stanbul | Istanbul | 34214 | Turkey | Details |
| Ankara Universitesi Tip Fakultesi Hastanesi-hematology ( Site 6001) | RECRUITING | Ankara | 06100 | Turkey | Details | |
| Trakya University ( Site 6005) | RECRUITING | Edirne | 22030 | Turkey | Details | |
| Ege Universitesi Hastanesi ( Site 6002) | RECRUITING | İzmir | 35100 | Turkey | Details | |
| Ondokuz Mayıs Universitesi-Oncology department ( Site 6004) | RECRUITING | Samsun | 55139 | Turkey | Details | |
| The Royal Cornwall Hospital-Haematology ( Site 7006) | RECRUITING | Truro | Cornwall | TR1 3LJ | United Kingdom | Details |
| University College London Hospital ( Site 7001) | RECRUITING | London | London, City Of | NW1 2PG | United Kingdom | Details |
| The Churchill Hospital ( Site 7002) | RECRUITING | Oxford | Oxfordshire | OX3 7LE | United Kingdom | Details |
| The Christie NHS Foundation Trust ( Site 7007) | RECRUITING | Manchester | m20 4bx | United Kingdom | Details |