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| NCT ID | NCT05480306 |
| Title | Phase 2 Study of DKN-01 in Colorectal Cancer (DeFianCe) |
| Acronym | DeFianCe |
| Recruitment | Active, not recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Leap Therapeutics, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | DEU |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| The University of Arizona Cancer Center | Tucson | Arizona | 85719 | United States | Details | |
| UCLA | Los Angeles | California | 90404 | United States | Details | |
| Florida Cancer Specialists & Research Institute (FCS) | Cape Coral | Florida | 33909 | United States | Details | |
| Florida Cancer Specialists & Research Institute | Fleming Island | Florida | 32003 | United States | Details | |
| Florida Cancer Specialists & Research Institute | Gainesville | Florida | 32605 | United States | Details | |
| Miami Cancer Institute | Miami | Florida | 33176 | United States | Details | |
| Florida Cancer Specialists & Research Institute | Wellington | Florida | 33414 | United States | Details | |
| Hematology Oncology Clinic | Baton Rouge | Louisiana | 70809 | United States | Details | |
| Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | United States | Details | |
| Oncology Hematology Associates - Springfield | Springfield | Missouri | 65807 | United States | Details | |
| Northwell Health | Lake Success | New York | 11020 | United States | Details | |
| New York University | New York | New York | 10016 | United States | Details | |
| Cornell University | New York | New York | 10021 | United States | Details | |
| Mount Sinai Medical Center - New York | New York | New York | 10029 | United States | Details | |
| White Plains Hospital | White Plains | New York | 10601 | United States | Details | |
| Messino Cancer Centers | Asheville | North Carolina | 28806 | United States | Details | |
| Duke University Medical Center | Durham | North Carolina | 27710 | United States | Details | |
| Wake Forest University | Winston-Salem | North Carolina | 27157 | United States | Details | |
| Prisma Health Cancer Institute - Faris | Greenville | South Carolina | 29605 | United States | Details | |
| Sanford Cancer Center | Sioux Falls | South Dakota | 57104 | United States | Details | |
| Tennessee Oncology | Chattanooga | Tennessee | 37404 | United States | Details | |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | United States | Details | |
| Tennessee Oncology | Nashville | Tennessee | 37203 | United States | Details | |
| MultiCare Tacoma General Hospital | Tacoma | Washington | 98405 | United States | Details | |
| University of Wisconsin Hospital and Clinics | Madison | Wisconsin | 53792 | United States | Details | |
| Universitaetsklinikum Hamburg-Eppendorf (UKE) - Universitaeres Cancer Center Hamburg (UCCH) | Hamburg | Germany | Details | |||
| Universitaetsklinikum Heidelberg (UKHD) - Nationales Centrum fuer Tumorerkrankungen Heidelberg (NCT) | Heidelberg | Germany | Details | |||
| SLK-Kliniken Heilbronn GmbH - Klinikum am Gesundbrunnen - Klinik fuer Innere Medizin III | Heilbronn | Germany | Details | |||
| Gemeinschaftspraxis fuer Haematologie und Onkologie - Magdeburg | Magdeburg | Germany | Details | |||
| Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz | Mainz | Germany | Details | |||
| Dong-A University Medical Center | Busan | Korea, Republic of | Details | |||
| Kyungpook National University Chilgok Hospital | Daegu | Korea, Republic of | Details | |||
| Gachon University Gil Medical Center | Incheon | Korea, Republic of | Details | |||
| Inha University Hospital | Incheon | Korea, Republic of | Details | |||
| CHA University - Bundang CHA General Hospital | Seongnam-si | Korea, Republic of | Details | |||
| Seoul National University Bundang Hospital | Seongnam-si | Korea, Republic of | Details | |||
| Asan Medical Center | Seoul | Korea, Republic of | Details | |||
| Samsung Medical Center | Seoul | Korea, Republic of | Details | |||
| Seoul National University Hospital | Seoul | Korea, Republic of | Details | |||
| The Catholic University of Korea - St. Vincent's Hospital | Suwon | Korea, Republic of | Details |