Clinical Trial Detail

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NCT ID	NCT05564377
Title	Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Recruitment	Recruiting
Gender	both
Phase	Phase II
Variant Requirements	Yes
Sponsors	National Cancer Institute (NCI)
Indications	ovarian carcinoma peritoneal carcinoma Her2-receptor negative breast cancer fallopian tube carcinoma breast cancer Advanced Solid Tumor endometrial carcinoma female reproductive organ cancer
Therapies	Selumetinib Binimetinib + Fulvestrant Binimetinib + Palbociclib Nilotinib + Paclitaxel Binimetinib + Fluorouracil + Leucovorin + Oxaliplatin Panitumumab + Sotorasib Binimetinib Fulvestrant Olaparib Olaparib + Selumetinib Alpelisib + Olaparib Neratinib Neratinib + Palbociclib Fluorouracil + Leucovorin + Oxaliplatin Ipatasertib + Paclitaxel
Age Groups:	senior \| adult \| child
Covered Countries	USA