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| NCT ID | NCT05633654 |
| Title | Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | Gilead Sciences |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ESP | DEU |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Alabama Oncology | RECRUITING | Birmingham | Alabama | 35243 | United States | Details |
| Alta Bates Summit Medical Center | RECRUITING | Berkeley | California | 94704 | United States | Details |
| Althaia Xarxa Assistencial de Manresa | RECRUITING | Manresa | 08242 | Spain | Details | |
| American Oncology Partners of Maryland, PA | WITHDRAWN | Bethesda | Maryland | 20817 | United States | Details |
| Anita Stewart Oncology Center | RECRUITING | Columbus | Ohio | 43221 | United States | Details |
| Arizona Oncology Associates | WITHDRAWN | Prescott Valley | Arizona | 86314 | United States | Details |
| Asante Rogue Regional Medical Center | RECRUITING | Medford | Oregon | 97504 | United States | Details |
| Ascension | RECRUITING | Grosse Pointe Woods | Michigan | 48236 | United States | Details |
| Ascension Providence Hospital Southfield Cancer Center | RECRUITING | Southfield | Michigan | 48075 | United States | Details |
| Ascension St. Francis Reiman Cancer Center | RECRUITING | Franklin | Wisconsin | 53132 | United States | Details |
| Atrium Health Wake Forest Baptist | RECRUITING | Winston-Salem | North Carolina | 27157 | United States | Details |
| Avera Cancer Institute | RECRUITING | Sioux Falls | South Dakota | 57105 | United States | Details |
| Ballad Health Cancer Care - Kingsport | RECRUITING | Kingsport | Tennessee | 37660 | United States | Details |
| Baptist Clinical Research Institute | RECRUITING | Saint Louis | Missouri | 63131 | United States | Details |
| Baystate Medical Center Inc. | RECRUITING | Springfield | Massachusetts | 01199 | United States | Details |
| Beth Israel Deaconess Medical Center | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Cancer and Hematology Centers of Western Michigan | RECRUITING | Grand Rapids | Michigan | 49503 | United States | Details |
| Cancer Care & Hematology Specialists | RECRUITING | Reno | Nevada | 89511 | United States | Details |
| Cancer Care Associates of York | RECRUITING | York | Pennsylvania | 17403 | United States | Details |
| Cancer Care Centers of Brevard, Inc | COMPLETED | Palm Bay | Florida | 32909 | United States | Details |
| Cancer Specialists of North Florida | RECRUITING | Jacksonville | Florida | 32256 | United States | Details |
| Carle Cancer Center | RECRUITING | Urbana | Illinois | 61801 | United States | Details |
| Cedars-Sinai Cancer at Beverly Hills | RECRUITING | Los Angeles | California | 90048 | United States | Details |
| Center for Biomedical Research, LLC | COMPLETED | Knoxville | Tennessee | 37909 | United States | Details |
| Clearview Cancer Institute | RECRUITING | Huntsville | Alabama | 35805 | United States | Details |
| Cleveland Clinic Florida, Martin North Hospital | RECRUITING | Stuart | Florida | 34994 | United States | Details |
| Clinical Research Alliance | WITHDRAWN | Westbury | New York | 11590 | United States | Details |
| Community Cancer Institute | RECRUITING | Clovis | California | 93611 | United States | Details |
| Compassionate Cancer Care Medical Group - Inc | RECRUITING | Fountain Valley | California | 92708 | United States | Details |
| Comprehensive Cancer Centers of Nevada | RECRUITING | Las Vegas | Nevada | 89169 | United States | Details |
| Cone Health Medical Group (Moses Cone Health System) | RECRUITING | Greensboro | North Carolina | 27403 | United States | Details |
| Consorcio Hospitalario Provincial de Castellón | RECRUITING | Castellón | 12002 | Spain | Details | |
| Dana Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Duke Cancer Institute | RECRUITING | Durham | North Carolina | 27710 | United States | Details |
| East Carolina University Health Medical Center | RECRUITING | Greenville | North Carolina | 27834 | United States | Details |
| Edward H. Kaplan MD & Associates - Hematology/Oncology of the North Shore | WITHDRAWN | Skokie | Illinois | 60076 | United States | Details |
| Edward Hospital | RECRUITING | Naperville | Illinois | 60540 | United States | Details |
| Elisabeth Krankenhaus Brustzentrum | RECRUITING | Kassel | 34117 | Germany | Details | |
| Emad Ibrahim, MD, INC | WITHDRAWN | Redlands | California | 92373 | United States | Details |
| FirstHealth Outpatient Cancer Center | COMPLETED | Pinehurst | North Carolina | 28374 | United States | Details |
| Franciscan Health Indianapolis | RECRUITING | Indianapolis | Indiana | 46237 | United States | Details |
| Franciscan Health Munster | RECRUITING | Munster | Indiana | 46321 | United States | Details |
| Good Samaritan Hospital | RECRUITING | Cincinnati | Ohio | 45220 | United States | Details |
| Greater Baltimore Medical Center | RECRUITING | Towson | Maryland | 21204 | United States | Details |
| Guthrie Clinical Research | RECRUITING | Sayre | Pennsylvania | 18840 | United States | Details |
| Hematology Oncology Associates of Central New York, PC | RECRUITING | East Syracuse | New York | 13057 | United States | Details |
| Hendrick Health System | RECRUITING | Abilene | Texas | 79601 | United States | Details |
| Henry Ford Health System | RECRUITING | Detroit | Michigan | 48202 | United States | Details |
| Hoag Memorial Hospital Presbyterian | RECRUITING | Newport Beach | California | 92663 | United States | Details |
| Hospital Clinic de Barcelona | RECRUITING | Barcelona | 08036 | Spain | Details | |
| Hospital Clinico Universitario de Valladolid | RECRUITING | Valladolid | 47003 | Spain | Details | |
| Hospital General Universitario De Elche | RECRUITING | Elche | 03203 | Spain | Details | |
| Hospital Universitario Morales Meseguer | RECRUITING | Murcia | 30008 | Spain | Details | |
| Hospital Universitary of Cruces | RECRUITING | Barakaldo | 48903 | Spain | Details | |
| HSHS Saint Mary's Hospital Medical Center - Green Bay | RECRUITING | Green Bay | Wisconsin | 54303 | United States | Details |
| HU Marqués de Valdecilla | RECRUITING | Santander | 39008 | Spain | Details | |
| Hunterdon Medical Center | RECRUITING | Flemington | New Jersey | 08822 | United States | Details |
| Huntsman Cancer Institute | RECRUITING | Salt Lake City | Utah | 84112 | United States | Details |
| Hämato-Onkologische Praxis im Medicum | RECRUITING | Bremen | 28209 | Germany | Details | |
| Hämatologie-Onkologie im Zentrum MVZ GmbH | RECRUITING | Augsburg | 86150 | Germany | Details | |
| Investigative Clinical Research of Indiana, LLC | RECRUITING | Indianapolis | Indiana | 46260 | United States | Details |
| InVO - Institut für Versorgungsforschung in der Onkologie GbR / Praxis für Hämatologie und Onkologie | RECRUITING | Koblenz | 56068 | Germany | Details | |
| Isabel la Catolica nº 1-3 | RECRUITING | Zaragoza | 50009 | Spain | Details | |
| IU Health Arnett Hospital | RECRUITING | Lafayette | Indiana | 47904 | United States | Details |
| James M Stockman Cancer Institute | RECRUITING | Frederick | Maryland | 21702 | United States | Details |
| Joe Arrington Cancer Research and Treatment Center | RECRUITING | Lubbock | Texas | 79410 | United States | Details |
| Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center | RECRUITING | Baltimore | Maryland | 21231 | United States | Details |
| Jupiter Medical Center | RECRUITING | Jupiter | Florida | 33458 | United States | Details |
| Klinikum Esslingen | RECRUITING | Esslingen | 73730 | Germany | Details | |
| Klinikum Worms Frauenklinik | RECRUITING | Worms | 67550 | Germany | Details | |
| Kootenai Health | RECRUITING | Coeur d'Alene | Idaho | 83814 | United States | Details |
| Lancaster General Health | RECRUITING | Lancaster | Pennsylvania | 17601 | United States | Details |
| Lankenau Medical Center | RECRUITING | Wynnewood | Pennsylvania | 19106 | United States | Details |
| Laura and Isaac Perlmutter Cancer Canter | RECRUITING | New York | New York | 10016 | United States | Details |
| Lineberger Comprehensive Cancer Center | RECRUITING | Chapel Hill | North Carolina | 27514 | United States | Details |
| Lipson Cancer Institute - Linden Oaks | RECRUITING | Rochester | New York | 14618 | United States | Details |
| Los Angeles Cancer Network | RECRUITING | Los Angeles | California | 90017 | United States | Details |
| Mary Bird Perkins Cancer Center | RECRUITING | Baton Rouge | Louisiana | 70809 | United States | Details |
| Mary Lanning Healthcare - Morrison Cancer Center | RECRUITING | Hastings | Nebraska | 68901 | United States | Details |
| Mayo Clinic Florida | RECRUITING | Jacksonville | Florida | 32224 | United States | Details |
| Mayo Clinic Hospital | RECRUITING | Phoenix | Arizona | 85054 | United States | Details |
| Mayo Clinic Rochester | RECRUITING | Rochester | Minnesota | 55905 | United States | Details |
| MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Medical Oncology Associates | WITHDRAWN | Spokane | Washington | 99208 | United States | Details |
| Medical Oncology Unit. A Coruña University Hospital | RECRUITING | A Coruña | 15006 | Spain | Details | |
| Medical University of South Carolina | RECRUITING | Charleston | South Carolina | 29425 | United States | Details |
| Medstar Franklin Square Medical Center | RECRUITING | Baltimore | Maryland | 21237 | United States | Details |
| Memorial Healthcare System | RECRUITING | Pembroke Pines | Florida | 33028 | United States | Details |
| Mercy Health | RECRUITING | Paducah | Kentucky | 42003 | United States | Details |
| Mercy Hospital | RECRUITING | Saint Louis | Missouri | 63141 | United States | Details |
| Mercy Medical Center | RECRUITING | Cedar Rapids | Iowa | 52403 | United States | Details |
| Metro Minnesota Community Oncology | RECRUITING | Saint Louis Park | Minnesota | 55426 | United States | Details |
| Midland Florida Clinical Research Center, L | WITHDRAWN | Orange City | Florida | 32763 | United States | Details |
| Minnesota Oncology Hematology, PA | RECRUITING | Maplewood | Minnesota | 55109 | United States | Details |
| Mission Cancer & Blood - John Stoddard Cancer Center | RECRUITING | Des Moines | Iowa | 50309 | United States | Details |
| Montefiore Medical Center | COMPLETED | Bronx | New York | 10467 | United States | Details |
| Monument Health Cancer Care Institute | RECRUITING | Rapid City | South Dakota | 57701 | United States | Details |
| Morton Plant Hospital - Bay Care | WITHDRAWN | Clearwater | Florida | 00337 | United States | Details |
| Mount Sinai Comprehensive Cancer Center | RECRUITING | Miami Beach | Florida | 33140 | United States | Details |
| MultiCare Regional Cancer Center - Tacoma | RECRUITING | Puyallup | Washington | 98372 | United States | Details |
| MVZ II der Niels Stensen Kliniken | RECRUITING | Georgsmarienhütte | 49124 | Germany | Details | |
| Nebraska Methodist Hospital (change from Chi Health Bergan Mercy) | RECRUITING | Omaha | Nebraska | 68124 | United States | Details |
| New England Cancer Specialists | RECRUITING | Scarborough | Maine | 04074 | United States | Details |
| New York Cancer and Blood Specialists | RECRUITING | Shirley | New York | 11967 | United States | Details |
| New York Oncology Hematology (NYOH) | WITHDRAWN | Amsterdam | New York | 12010 | United States | Details |
| NorthShore University Healthsystem | RECRUITING | Evanston | Illinois | 60201 | United States | Details |
| Northside Hospital | RECRUITING | Atlanta | Georgia | 30342 | United States | Details |
| Northwell Health | RECRUITING | Lake Success | New York | 11042 | United States | Details |
| Northwest Georgia Oncology Centers, PC | RECRUITING | Marietta | Georgia | 30060 | United States | Details |
| Northwest Medical Specialties, PLLC | RECRUITING | Puyallup | Washington | 98373 | United States | Details |
| Northwestern Medicine | RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| Norton Healthcare, Inc. | RECRUITING | Louisville | Kentucky | 40207 | United States | Details |
| Norwalk Hospital | RECRUITING | Danbury | Connecticut | 06810 | United States | Details |
| Ohio Health Research Institute | RECRUITING | Columbus | Ohio | 43214 | United States | Details |
| Ohio State University CRS | RECRUITING | Columbus | Ohio | 43212 | United States | Details |
| Oncology and Hematology Associates of Southwest Virginia, Inc | RECRUITING | Wytheville | Virginia | 24382 | United States | Details |
| Oncology Hematology Care, Inc. | RECRUITING | Cincinnati | Ohio | 45242 | United States | Details |
| Oncology Hematology West - Methodist | RECRUITING | Omaha | Nebraska | 68114 | United States | Details |
| Oregon Health & Science University | RECRUITING | Portland | Oregon | 97239 | United States | Details |
| Orlando Health | RECRUITING | Orlando | Florida | 32806 | United States | Details |
| Overlook Medical Center | RECRUITING | Summit | New Jersey | 07901 | United States | Details |
| Palo Verde Hematology Oncology | RECRUITING | Glendale | Arizona | 85304 | United States | Details |
| Pearlman Cancer Center | RECRUITING | Valdosta | Georgia | 31602 | United States | Details |
| Piedmont Cancer Institute | RECRUITING | Atlanta | Georgia | 30318 | United States | Details |
| PIH Health Whittier Hospital | RECRUITING | Downey | California | 90241 | United States | Details |
| Providence Cancer Institute - Oncology Clinical Trials | WITHDRAWN | Portland | Oregon | 97213 | United States | Details |
| Providence Health | RECRUITING | Providence | Rhode Island | 02905 | United States | Details |
| Providence Regional Cancer System | RECRUITING | Lacey | Washington | 98503 | United States | Details |
| Reading Hospital and Medical Center | WITHDRAWN | West Reading | Pennsylvania | 19611 | United States | Details |
| Regional Cancer Care Associates LLC | RECRUITING | East Brunswick | New Jersey | 08816 | United States | Details |
| Roswell Park Cancer Institute | RECRUITING | Buffalo | New York | 14263 | United States | Details |
| Rush University Medical Center | RECRUITING | Chicago | Illinois | 60612 | United States | Details |
| Rutgers Health | RECRUITING | New Brunswick | New Jersey | 08901 | United States | Details |
| Sacred Heart Medical Oncology Group | COMPLETED | Pensacola | Florida | 32504 | United States | Details |
| Saint Luke's University Hospital | RECRUITING | Bethlehem | Pennsylvania | 18015 | United States | Details |
| Samaritan Hospital | RECRUITING | Corvallis | Oregon | 97330 | United States | Details |
| San Juan Oncology Associates | RECRUITING | Farmington | New Mexico | 87401 | United States | Details |
| Sansum Clinic | RECRUITING | Santa Barbara | California | 93105 | United States | Details |
| Sinai Hospital of Baltimore, Inc. | RECRUITING | Baltimore | Maryland | 21215 | United States | Details |
| Spartanburg Medical Center | RECRUITING | Spartanburg | South Carolina | 29303 | United States | Details |
| Springfield Clinic LLP | COMPLETED | Springfield | Illinois | 62702 | United States | Details |
| St Lukes Mountain States Tumor Institute | COMPLETED | Boise | Idaho | 83712 | United States | Details |
| St. Agnes Hospital | RECRUITING | Baltimore | Maryland | 21229 | United States | Details |
| St. Charles Health System, Inc. DBA St. Charles Medical Center | RECRUITING | Bend | Oregon | 97701 | United States | Details |
| St. Elisabeth Krankenhaus GmbH | RECRUITING | Köln | 50935 | Germany | Details | |
| St. Johannes Hospital | RECRUITING | Dortmund | 44137 | Germany | Details | |
| St. Joseph's Hospital | WITHDRAWN | Tampa | Florida | 33614 | United States | Details |
| Stamford Hospital | RECRUITING | Stamford | Connecticut | 06902 | United States | Details |
| Stockton Hematology Oncology Medical Group | RECRUITING | Stockton | California | 95204 | United States | Details |
| Stony Brook Medicine | RECRUITING | Stony Brook | New York | 11794 | United States | Details |
| Studien GbR Braunschweig | RECRUITING | Braunschweig | 38100 | Germany | Details | |
| Summit Medical Group, P.A. | COMPLETED | Florham Park | New Jersey | 07932 | United States | Details |
| SUNY Upstate Medical University | RECRUITING | Syracuse | New York | 13210 | United States | Details |
| Sutter Institute for Medical Research | RECRUITING | Sacramento | California | 95816 | United States | Details |
| Sylvester Comprehensive Cancer Center | RECRUITING | Plantation | Florida | 33324 | United States | Details |
| Texas Oncology | RECRUITING | Austin | Texas | 78731 | United States | Details |
| Texas Oncology | RECRUITING | El Paso | Texas | 79902 | United States | Details |
| Texas Oncology | RECRUITING | San Antonio | Texas | 78240 | United States | Details |
| ThedaCare Regional Cancer Center | RECRUITING | Appleton | Wisconsin | 54911 | United States | Details |
| Toledo Clinic Cancer Center | NOT_YET_RECRUITING | Toledo | Ohio | 43623 | United States | Details |
| Trinity Health St. Joseph Mercy Ann Arbor | RECRUITING | Ypsilanti | Michigan | 48197 | United States | Details |
| Tufts Medical Center | RECRUITING | Boston | Massachusetts | 02111 | United States | Details |
| UCSF Medical Center | RECRUITING | San Francisco | California | 94143 | United States | Details |
| UNC Nash Cancer Center | WITHDRAWN | Rocky Mount | North Carolina | 27804 | United States | Details |
| UNC Rex Cancer Center | RECRUITING | Raleigh | North Carolina | 27607 | United States | Details |
| University Cancer & Blood Center, LLC. | RECRUITING | Athens | Georgia | 30607 | United States | Details |
| University Medical Center New Orleans | COMPLETED | New Orleans | Louisiana | 70112 | United States | Details |
| University of Colorado Cancer Center | RECRUITING | Aurora | Colorado | 80045 | United States | Details |
| University of Florida | WITHDRAWN | Gainesville | Florida | 32610 | United States | Details |
| University of Illinois | WITHDRAWN | Chicago | Illinois | 60612 | United States | Details |
| University of Iowa Hospitals and Clinics | RECRUITING | Fairfield | Iowa | 52556 | United States | Details |
| University of Kentucky | COMPLETED | Lexington | Kentucky | 40536 | United States | Details |
| University of Massachusetts Worcester | RECRUITING | Worcester | Massachusetts | 01655 | United States | Details |
| University of Minnesota Medical Center, Fairview | RECRUITING | Minneapolis | Minnesota | 55455 | United States | Details |
| University of New Mexico | RECRUITING | Albuquerque | New Mexico | 87131 | United States | Details |
| University of Oklahoma Health Sciences Center | RECRUITING | Oklahoma City | Oklahoma | 73104 | United States | Details |
| University of Pennsylvania Abramson Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| University of Tennessee | RECRUITING | Knoxville | Tennessee | 37920 | United States | Details |
| University of Virginia | RECRUITING | Charlottesville | Virginia | 22908 | United States | Details |
| University of Washington | COMPLETED | Renton | Washington | 98055 | United States | Details |
| University of Wisconsin | RECRUITING | Madison | Wisconsin | 53792 | United States | Details |
| Universitätsklinikum Mannheim | RECRUITING | Mannheim | 68167 | Germany | Details | |
| USC Norris Comprehensive Cancer Center | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| Virginia Commonwealth University Medical Center | COMPLETED | Richmond | Virginia | 23298 | United States | Details |
| Virginia Piper Cancer Center (Allina Health) | RECRUITING | Minneapolis | Minnesota | 55407 | United States | Details |
| West Suburban Medical Center- River Forest | RECRUITING | River Forest | Illinois | 60305 | United States | Details |
| West Virginia University Hospital | RECRUITING | Morgantown | West Virginia | 26505 | United States | Details |
| Weston Hospital | RECRUITING | Weston | Florida | 33331 | United States | Details |
| White Plains Hospital Physician Associates | RECRUITING | White Plains | New York | 10601 | United States | Details |
| Willamette Valley Cancer Institute and Research Center | RECRUITING | Eugene | Oregon | 97401 | United States | Details |
| William Beaumont Hospital | RECRUITING | Royal Oak | Michigan | 48073 | United States | Details |
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