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| NCT ID | NCT06140836 |
| Title | A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | Yes |
| Sponsors | Bristol-Myers Squibb |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | TUR | ROU | POL | NLD | ITA | HUN | GRC | FRA | ESP | DEU | CHE | CAN | BRA | AUT | ARG |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Local Institution - 0136 | WITHDRAWN | Augusta | Georgia | 30912 | United States | Details |
| Local Institution - 0221 | NOT_YET_RECRUITING | Des Moines | Iowa | 50309 | United States | Details |
| Massachusetts General Hospital | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Beth Israel Deaconess Medical Center | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Local Institution - 0217 | NOT_YET_RECRUITING | Brooklyn | New York | 11220 | United States | Details |
| Perlmutter Cancer Center at NYU Langone Hospital - Long Island | RECRUITING | Mineola | New York | 11501 | United States | Details |
| Laura and Isaac Perlmutter Cancer Center | RECRUITING | New York | New York | 10016 | United States | Details |
| SUNY Upstate Medical University | RECRUITING | Syracuse | New York | 13210 | United States | Details |
| Local Institution - 0214 | NOT_YET_RECRUITING | Tacoma | Washington | 98405 | United States | Details |
| Local Institution - 0061 | WITHDRAWN | Milwaukee | Wisconsin | 53226 | United States | Details |
| Hospital Británico de Buenos Aires | RECRUITING | Ciudad autónoma de Buenos Aires | Buenos Aires | 1280 | Argentina | Details |
| Instituto Alexander Fleming | RECRUITING | Ciudad Autónoma de Buenos Aires | Buenos Aires | C1426ANZ | Argentina | Details |
| Hospital Italiano de Buenos Aires | RECRUITING | ABB | Ciudad Autónoma De Buenos Aires | C1199ABB | Argentina | Details |
| Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) | RECRUITING | Buenos Aires | 1431 | Argentina | Details | |
| Instituto de Oncología Angel H. Roffo | RECRUITING | Buenos Aires | C1417DTB | Argentina | Details | |
| Instituto Oncológico de Córdoba | RECRUITING | Córdoba | 5000 | Argentina | Details | |
| Klinik Floridsdorf | RECRUITING | Wien | 1210 | Austria | Details | |
| Hospital Luxemburgo | RECRUITING | Belo Horizonte | Minas Gerais | 30380-490 | Brazil | Details |
| Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa | RECRUITING | Porto Alegre | Rio Grande Do Sul | 90110-270 | Brazil | Details |
| Hospital São Lucas da PUCRS | RECRUITING | Porto Alegre | Rio Grande Do Sul | 90610-000 | Brazil | Details |
| Fundação Pio XII - Hospital de Câncer de Barretos | RECRUITING | Barretos | São Paulo | 14784400 | Brazil | Details |
| Hospital Sírio Libanês | RECRUITING | Sao Paulo | São Paulo | 01308-060 | Brazil | Details |
| Hospital Paulistano | RECRUITING | Sao Paulo | São Paulo | 01321-001 | Brazil | Details |
| Fundação Faculdade Regional de Medicina de São José do Rio Preto | RECRUITING | São José do Rio Preto | São Paulo | 15090000 | Brazil | Details |
| Hospital São Lucas de Copacabana | RECRUITING | Rio de Janeiro | 22061-080 | Brazil | Details | |
| Grupo Oncoclinicas Botafogo | RECRUITING | Rio de Janeiro | 22250-905 | Brazil | Details | |
| Instituto D'Or de Pesquisa e Ensino (IDOR) | RECRUITING | São Paulo | 01401-002 | Brazil | Details | |
| Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein | RECRUITING | São Paulo | 05652-900 | Brazil | Details | |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Centre integre universitaire de sante et de services sociaux de la Mauricie-et-du-centre-du-quebec | RECRUITING | Trois-Rivières | Quebec | G8Z 3R9 | Canada | Details |
| FALP | RECRUITING | Santiago | Región Metropolitana De Santiago | 7500921 | Chile | Details |
| Oncocentro Apys | RECRUITING | Viña del Mar | Valparaíso | 2520598 | Chile | Details |
| Beijing Cancer hospital | RECRUITING | Beijing | Beijing | 100142 | China | Details |
| Army Medical Center of PLA | RECRUITING | Chongqing | Chongqing | 400042 | China | Details |
| Local Institution - 0192 | WITHDRAWN | Fuzhou | Fujian | 350000 | China | Details |
| The First Affiliated hospital of Xiamen University | RECRUITING | Xiamen | Fujian | 361003 | China | Details |
| The First Affiliated Hospital of Guangzhou Medical University | RECRUITING | Guangzhou | Guangdong | 510120 | China | Details |
| The First Affiliated Hospital of Guangxi Medical University | RECRUITING | Nanning | Guangxi | 530000 | China | Details |
| Affiliated Cancer Hospital of Harbin Medical University | RECRUITING | Harbin | Heilongjiang | 150000 | China | Details |
| Henan Cancer Hospital | RECRUITING | Zhengzhou | Henan | 450003 | China | Details |
| Hubei Cancer Hospital | RECRUITING | Wuhan Shi | Hubei | 430079 | China | Details |
| Local Institution - 0203 | WITHDRAWN | Wuhan | Hubei | 430022 | China | Details |
| Hunan Province People'S Hospital | RECRUITING | Changsha | Hunan | 410000 | China | Details |
| Local Institution - 0165 | WITHDRAWN | Changsha | Hunan | 410013 | China | Details |
| Jiangsu Province Hospital Of Chinese Medicine | RECRUITING | Nanjing | Jiangsu | 210029 | China | Details |
| The First Affiliated Hospital of Nanchang University | RECRUITING | Nanchang | Jiangxi | 330006 | China | Details |
| Jilin Cancer Hospital | RECRUITING | Changchun | Jilin | 130012 | China | Details |
| The First Affiliated Hospital of Xi'an Jiaotong University | RECRUITING | Xi'an | Shaanxi | 710061 | China | Details |
| Shandong Cancer Hospital | RECRUITING | Jinan | Shandong | 250000 | China | Details |
| Local Institution - 0205 | WITHDRAWN | Linyi | Shandong | 276027 | China | Details |
| Shanghai Chest Hospital | RECRUITING | Shanghai | Shanghai | 200030 | China | Details |
| Fudan University Shanghai Cancer Center | RECRUITING | Shanghai | Shanghai | 200032 | China | Details |
| Local Institution - 0170 | WITHDRAWN | Chengdu | Sichuan | 610041 | China | Details |
| West China Hospital, Sichuan University | RECRUITING | Chengdu | Sichuan | 610044 | China | Details |
| Local Institution - 0204 | WITHDRAWN | Kunming | Yunnan | 650106 | China | Details |
| Local Institution - 0206 | WITHDRAWN | Hangzhou | Zhejiang | 310003 | China | Details |
| Zhejiang Cancer Hospital | RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Nouvel Hôpital Civil (NHC) | RECRUITING | Strasbourg | Alsace | 67091 | France | Details |
| CHU Bordeaux Haut-Leveque | RECRUITING | Pessac | Aquitaine | 33600 | France | Details |
| Centre Georges François Leclerc | RECRUITING | Dijon | Côte-d'Or | 21079 | France | Details |
| Hopital Charles Nicolle C H U Rouen | RECRUITING | Rouen | Haute-Normandie | 76031 | France | Details |
| Chu Grenoble Alpes | RECRUITING | La Tronche | Isère | 38700 | France | Details |
| Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes | RECRUITING | Saint-Herblain | Loire-Atlantique | 44800 | France | Details |
| Centre Hospitalier Lyon Sud | RECRUITING | Pierre-Bénite | Rhône | 69310 | France | Details |
| Hopitaux Universitaires Paris Centre-Hopital Cochin | RECRUITING | Paris | 75014 | France | Details | |
| Klinikum Esslingen | RECRUITING | Esslingen | Baden-Württemberg | 73730 | Germany | Details |
| Klinikum Würzburg Mitte | RECRUITING | Wuerzburg | Bayern | 97074 | Germany | Details |
| Pius Hospital Oldenburg | RECRUITING | Oldenburg | Niedersachsen | 26121 | Germany | Details |
| Evangelische Lungenklinik Berlin | RECRUITING | Berlin | 13125 | Germany | Details | |
| Universitaetsklinikum Carl Gustav Carus Dresden | RECRUITING | Dresden | 01307 | Germany | Details | |
| Asklepios Klinik Gauting GmbH | RECRUITING | Gauting | 82131 | Germany | Details | |
| Lungenfachklinik Immenhausen | RECRUITING | Immenhausen | 34376 | Germany | Details | |
| Universitaetsklinikum Koeln | RECRUITING | Köln | 50937 | Germany | Details | |
| Marienhaus Klinikum Mainz | RECRUITING | Mainz | 55131 | Germany | Details | |
| University Hospital of Patras | RECRUITING | Patras | Achaḯa | 26504 | Greece | Details |
| Thoracic General Hospital of Athens "I Sotiria" | RECRUITING | Athens | Attikí | 115 27 | Greece | Details |
| Attikon General University Hospital | RECRUITING | Chaidari | Attikí | 124 62 | Greece | Details |
| Theagenio Hospital | RECRUITING | Thessaloniki | Kentrikí Makedonía | 540 07 | Greece | Details |
| Országos Korányi Pulmonológiai Intézet | RECRUITING | Budapest | 1121 | Hungary | Details | |
| Local Institution - 0218 | NOT_YET_RECRUITING | New Delhi | Delhi | 110029 | India | Details |
| Local Institution - 0076 | NOT_YET_RECRUITING | New Delhi | Delhi | 110085 | India | Details |
| Local Institution - 0102 | NOT_YET_RECRUITING | Ahmedabad | Gujarat | 380054 | India | Details |
| Local Institution - 0118 | NOT_YET_RECRUITING | Ahmedabad | Gujarat | 380060 | India | Details |
| Local Institution - 0117 | NOT_YET_RECRUITING | Gurgaon | Haryana | 122002 | India | Details |
| Local Institution - 0044 | NOT_YET_RECRUITING | Gurugram | Haryana | 122001 | India | Details |
| Local Institution - 0082 | NOT_YET_RECRUITING | Bengaluru | Karnataka | 560017 | India | Details |
| Local Institution - 0219 | NOT_YET_RECRUITING | Thiruvananthapuram | Kerala | 695011 | India | Details |
| Local Institution - 0065 | NOT_YET_RECRUITING | Mumbai | Maharashtra | 400004 | India | Details |
| Local Institution - 0048 | NOT_YET_RECRUITING | Mumbai | Maharashtra | 400012 | India | Details |
| Local Institution - 0045 | NOT_YET_RECRUITING | Pune | Maharashtra | 411001 | India | Details |
| Local Institution - 0049 | NOT_YET_RECRUITING | Pune | Maharashtra | 411004 | India | Details |
| Local Institution - 0220 | NOT_YET_RECRUITING | Hyderabad | Telangana | 500082 | India | Details |
| Fondazione IRCCS Istituto Nazionale dei Tumori | RECRUITING | Milan | Lombardia | 20133 | Italy | Details |
| Fondazione IRCCS San Gerardo dei Tintori | RECRUITING | Monza | Lombardia | 20900 | Italy | Details |
| A.O.R.N. Ospedale dei Colli - Monaldi V. | RECRUITING | Naples | Napoli | 80131 | Italy | Details |
| Istituto Nazionale Tumori Regina Elena | RECRUITING | Rome | Roma | 00144 | Italy | Details |
| Cro-Irccs | RECRUITING | Aviano | 33081 | Italy | Details | |
| Nagoya University Hospital | RECRUITING | Nagoya | Aichi | 466-8560 | Japan | Details |
| National Cancer Center Hospital East | RECRUITING | Kashiwa | Chiba | 277-8577 | Japan | Details |
| National Hospital Organization Shikoku Cancer Center | RECRUITING | Matsuyama | Ehime | 791-0280 | Japan | Details |
| Hokkaido University Hospital | RECRUITING | Sapporo | Hokkaido | 060-8648 | Japan | Details |
| Kanagawa cancer center | RECRUITING | Yokohama | Kanagawa | 2418515 | Japan | Details |
| Sendai Kosei Hospital | RECRUITING | Sendai | Miyagi | 9800873 | Japan | Details |
| Tokyo Metropolitan Komagome Hospital | RECRUITING | Bunkyo ku | Tokyo | 113-8677 | Japan | Details |
| Tottori University Hospital | RECRUITING | Yonago | Tottori | 683-8504 | Japan | Details |
| National Hospital Organization Kyushu Cancer Center | RECRUITING | Fukuoka | 811-1395 | Japan | Details | |
| Osaka City General Hospital | RECRUITING | Osaka | 534-0021 | Japan | Details | |
| Osaka International Cancer Institute | RECRUITING | Osaka | 541-8567 | Japan | Details | |
| Tokyo Metropolitan Police Hospital | RECRUITING | Tokyo | 164-8541 | Japan | Details | |
| Chungbuk National University Hospital | RECRUITING | Cheongju-si | Chungcheongbuk-do [Chungbuk] | 28644 | Korea, Republic of | Details |
| Seoul National University Bundang Hospital | RECRUITING | Seongnam | Kyǒnggi-do | 13620 | Korea, Republic of | Details |
| Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 03722 | Korea, Republic of | Details |
| Asan Medical Center | RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 05505 | Korea, Republic of | Details |
| Samsung Medical Center | RECRUITING | Seoul | Seoul-teukbyeolsi [Seoul] | 06351 | Korea, Republic of | Details |
| Local Institution - 0223 | NOT_YET_RECRUITING | Kuala Lumpur | Wilayah Persekutuan Kuala Lumpur | 50586 | Malaysia | Details |
| Local Institution - 0237 | NOT_YET_RECRUITING | Kuala Lumpur | Wilayah Persekutuan Kuala Lumpur | 50586 | Malaysia | Details |
| Local Institution - 0222 | NOT_YET_RECRUITING | Lembah Pantai | Wilayah Persekutuan Kuala Lumpur | 59100 | Malaysia | Details |
| Local Institution - 0226 | WITHDRAWN | Lembah Pantai | Wilayah Persekutuan Kuala Lumpur | 59100 | Malaysia | Details |
| Local Institution - 0224 | NOT_YET_RECRUITING | Putrajaya | Wilayah Persekutuan Kuala Lumpur | 62250 | Malaysia | Details |
| Local Institution - 0216 | NOT_YET_RECRUITING | Amsterdam | Noord-Holland | 1081 HV | Netherlands | Details |
| Local Institution - 0215 | NOT_YET_RECRUITING | Groningen | 9713 GZ | Netherlands | Details | |
| Instytut Genetyki i Immunologii GENIM | RECRUITING | Lublin | Lubelskie | 20-609 | Poland | Details |
| Warmińsko - Mazurskie Centrum Chorób Płuc w Olsztynie | RECRUITING | Olsztyn | Warmińsko-mazurskie | 10-357 | Poland | Details |
| SC Memorial Healthcare International SRL | RECRUITING | Bucharest | București | 013812 | Romania | Details |
| Institutul Oncologic Bucuresti | RECRUITING | Bucharest | București | 022328 | Romania | Details |
| Centrul de Oncologie "Sfântul Nectarie" | RECRUITING | Craiova | Dolj | 200746 | Romania | Details |
| Institutul Oncologic Cluj | RECRUITING | Cluj | 400015 | Romania | Details | |
| S.C. Centrul de Oncologie Euroclinic S.R.L. | RECRUITING | Iași | 700106 | Romania | Details | |
| CHUAC-Hospital Teresa Herrera | RECRUITING | A Coruña | A Coruña [La Coruña] | 15006 | Spain | Details |
| CHUS - Hospital Clinico Universitario | RECRUITING | Santiago de Compostela | A Coruña [La Coruña] | 15706 | Spain | Details |
| Hospital Universitari Vall d'Hebron | RECRUITING | Barcelona | Barcelona [Barcelona] | 08035 | Spain | Details |
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | Madrid, Comunidad De | 28041 | Spain | Details |
| Hospital Universitario Puerta de Hierro Majadahonda | RECRUITING | Majadahonda | Madrid, Comunidad De | 28222 | Spain | Details |
| H.R.U Málaga - Hospital General | RECRUITING | Málaga | 29011 | Spain | Details | |
| Hospital Universitario Virgen Del Rocio | RECRUITING | Sevilla | 41013 | Spain | Details | |
| Hospital Universitari i Politecnic La Fe | RECRUITING | València | 46026 | Spain | Details | |
| Kantonspital Baden | RECRUITING | Baden | Aargau | 5404 | Switzerland | Details |
| Local Institution - 0086 | NOT_YET_RECRUITING | Yenimahalle | Ankara | 06200 | Turkey | Details |
| Adana Medical Park Seyhan Hastanesi | RECRUITING | Adana | 01140 | Turkey | Details | |
| Local Institution - 0084 | NOT_YET_RECRUITING | Ankara | 06010 | Turkey | Details | |
| Medipol Mega Universite Hastanesi | RECRUITING | Istanbul | 34214 | Turkey | Details | |
| Local Institution - 0097 | NOT_YET_RECRUITING | Istanbul | 34440 | Turkey | Details | |
| VM Medical Park Pendik Hospital | RECRUITING | Istanbul | 34899 | Turkey | Details | |
| Local Institution - 0085 | NOT_YET_RECRUITING | Sakarya | 0 | Turkey | Details |