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| NCT ID | NCT06948448 |
| Title | A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase II |
| Variant Requirements | Yes |
| Sponsors | Ono Pharmaceutical Co. Ltd |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | CAN |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Mayo Clinic Arizona | RECRUITING | Phoenix | Arizona | 85054 | United States | Details |
| USC Norris Comprehensive Cancer Center | RECRUITING | Los Angeles | California | 90033 | United States | Details |
| Rocky Mountain Cancer Centers, LLP | RECRUITING | Lone Tree | Colorado | 80124 | United States | Details |
| Mayo Clinic Florida | RECRUITING | Jacksonville | Florida | 32224 | United States | Details |
| The Ohio State University Comprehensive Cancer Center | RECRUITING | Columbus | Ohio | 43221 | United States | Details |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19107 | United States | Details |
| Baylor Scott & White Medical Center | RECRUITING | Temple | Texas | 76508 | United States | Details |
| Virginia Oncology Associates | RECRUITING | Norfolk | Virginia | 23502 | United States | Details |
| Blue Ridge Cancer Care | RECRUITING | Salem | Virginia | 24153 | United States | Details |
| Princess Margaret Cancer Centre- University Health Network | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| CHU Besançon - Hôpital Jean Minjoz | RECRUITING | Besançon | Doubs | France | Details | |
| CHU Bordeaux - Hôpital Haut-Lévêque | RECRUITING | Pessac | Gironde | France | Details | |
| Chru De Nantes Hotel-Dieu | RECRUITING | Nantes | Loire Atlantique | France | Details | |
| Hôpital de la Timone | RECRUITING | Marseille | Marseille | France | Details | |
| Hôpital Européen Georges Pompidou | RECRUITING | Paris | Paris | France | Details | |
| Hôpital Saint-Antoine | RECRUITING | Paris | Paris | France | Details | |
| Centre Leon Berard | RECRUITING | Lyon | Rhone | France | Details | |
| CHU Poitiers - Hôpital la Milétrie | RECRUITING | Poitiers | Vienne | France | Details | |
| Istituto Clinico Humanitas | RECRUITING | Milan | Italy | Italy | Details | |
| Istituto Europeo di Oncologia | RECRUITING | Milan | Italy | Italy | Details | |
| Kobe City Medical Center General Hospital | RECRUITING | Hyōgo | Kobe-shi | Japan | Details | |
| National Hospital Organization Osaka National Hospital | RECRUITING | Osaka | Osaka-shi | Japan | Details | |
| Osaka General Medical Center | RECRUITING | Osaka | Osaka-shi | Japan | Details | |
| Osaka International Cancer Institute | RECRUITING | Osaka | Osaka-shi | Japan | Details | |
| Hospital Universitario Reina Sofia | RECRUITING | Córdoba | Córdoba | Spain | Details | |
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | Madrid | Spain | Details | |
| Hospital Universitario Virgen del Rocio | RECRUITING | Seville | Sevilla | Spain | Details | |
| Hospital General Universitario de Valencia | RECRUITING | Valencia | Valencia | Spain | Details |