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| NCT ID | NCT07100106 |
| Title | A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer (MoonROSE) |
| Acronym | MoonROSE |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase Ib/II |
| Variant Requirements | No |
| Sponsors | Genentech, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | ITA | FRA | ESP | DEU | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| City of Hope | RECRUITING | Duarte | California | 91010 | United States | Details |
| City of Hope - Orange County Lennar Foundation Cancer Center | RECRUITING | Irvine | California | 92618 | United States | Details |
| UC San Diego Moores Cancer Center | RECRUITING | La Jolla | California | 92093-1503 | United States | Details |
| UCSF Helen Diller Family CCC | RECRUITING | San Francisco | California | 94158 | United States | Details |
| Moffitt Cancer Center | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| Winship Cancer Institute of Emory University | RECRUITING | Atlanta | Georgia | 30322-1013 | United States | Details |
| City of Hope® Cancer Center Chicago | RECRUITING | Zion | Illinois | 60099 | United States | Details |
| Barbara Ann Karmanos Cancer Institute | RECRUITING | Detroit | Maine | 48201-2013 | United States | Details |
| Washington University Siteman Cancer Center | RECRUITING | St Louis | Missouri | 63110-1010 | United States | Details |
| Rutgers Cancer Institute of New Jersey | RECRUITING | New Brunswick | New Jersey | 08901-1914 | United States | Details |
| New York Cancer & Blood Specialists | RECRUITING | East Patchogue | New York | 11772 | United States | Details |
| Levine Cancer Institute | RECRUITING | Charlotte | North Carolina | 28204 | United States | Details |
| University of Pennsylvania - Abramson Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19104 | United States | Details |
| UPMC - Hillman Cancer Center | RECRUITING | Pittsburgh | Pennsylvania | 15213-3108 | United States | Details |
| Vanderbilt Breast Center at One Hundred Oaks | RECRUITING | Nashville | Tennessee | 37204-3609 | United States | Details |
| Texas Oncology (Worth) - USOR | RECRUITING | Dallas | Texas | 75246-2003 | United States | Details |
| Virginia Oncology Associates (Norfolk) - USOR | RECRUITING | Norfolk | Virginia | 23502-2800 | United States | Details |
| St Vincent's Hospital Sydney | RECRUITING | Darlinghurst | New South Wales | 2010 | Australia | Details |
| Cancer Research SA | RECRUITING | Adelaide | South Australia | 5000 | Australia | Details |
| Hospital do Cancer de Pernambuco - HCP | RECRUITING | Recife | Pernambuco | 50040-000 | Brazil | Details |
| ONCOSITE Centro de Pesquisa Clínica Em Oncologia | RECRUITING | Ijuí | Rio Grande do Sul | 98700-000 | Brazil | Details |
| Irmandade Da Santa Casa de Misericordia de Porto Alegre | RECRUITING | Porto Alegre | Rio Grande do Sul | 90035-074 | Brazil | Details |
| Hospital de Clinicas de Porto Alegre (HCPA) - PPDS | RECRUITING | Porto Alegre | Rio Grande do Sul | 90560-030 | Brazil | Details |
| Instituto Do Câncer Do Estado de São Paulo Octávio Frias de Oliveira - ICESP | RECRUITING | São Paulo | 01246-000 | Brazil | Details | |
| Princess Margaret Hospital | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Fudan University Shanghai Cancer Center - Pudong Campus | RECRUITING | Shanghai | Shanghai Municipality | 201321 | China | Details |
| Institut Jean Godinot | RECRUITING | Reims | Champagne-Ardenne | 51100 | France | Details |
| Gustave Roussy | RECRUITING | Villejuif | Val-de-Marne | 94805 | France | Details |
| Centre Francois Baclesse | RECRUITING | Caen | 14076 | France | Details | |
| Centre Oscar Lambret | RECRUITING | Lille | 59020 | France | Details | |
| Centre Eugene Marquis | RECRUITING | Rennes | 35042 | France | Details | |
| KEM - Evang. Huyssens-Stiftung Essen-Huttrop | RECRUITING | Essen | North Rhine-Westphalia | 45136 | Germany | Details |
| Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST S.r.l - PPDS | RECRUITING | Meldola | Emilia-Romagna | 47014 | Italy | Details |
| ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia | RECRUITING | Brescia | Lombardy | 25123 | Italy | Details |
| Gangnam Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | Seoul Teugbyeolsi | 6273 | South Korea | Details |
| Seoul National University Bundang Hospital | RECRUITING | Seongnam-si | 13620 | South Korea | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 03080 | South Korea | Details | |
| Asan Medical Center. | RECRUITING | Seoul | 05505 | South Korea | Details | |
| The Catholic University of Korea, Seoul St. Mary's Hospital | RECRUITING | Seoul | 06591 | South Korea | Details | |
| Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | 3722 | South Korea | Details | |
| Instituto de Investigacion Oncologica Vall dHebron (VHIO) - EPON | RECRUITING | Barcelona | 08035 | Spain | Details | |
| Hospital Beata Maria Ana | RECRUITING | Madrid | 28007 | Spain | Details | |
| Hospital General Universitario Gregorio Maranon | RECRUITING | Madrid | 28007 | Spain | Details | |
| Hospital Universitario 12 de Octubre | RECRUITING | Madrid | 28041 | Spain | Details | |
| Hospital Clinico Universitario de Valencia | RECRUITING | Valencia | 46010 | Spain | Details |