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| NCT ID | NCT07720284 |
| Title | An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC (TU-04) |
| Acronym | TU-04 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase III |
| Variant Requirements | No |
| Sponsors | AstraZeneca |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | POL | ITA | GBR | FRA | ESP | DEU | CAN | BRA | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Research Site | NOT_YET_RECRUITING | Hot Springs | Arkansas | 71913 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Little Rock | Arkansas | 72205 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Little Rock | Arkansas | 72211 | United States | Details |
| Research Site | NOT_YET_RECRUITING | San Francisco | California | 94143 | United States | Details |
| Research Site | WITHDRAWN | Chicago | Illinois | 60637 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Kansas City | Missouri | 64132 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Lincoln | Nebraska | 68506 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Omaha | Nebraska | 68130 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Albany | New York | 12208 | United States | Details |
| Research Site | NOT_YET_RECRUITING | New York | New York | 10065 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Cleveland | Ohio | 44195 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Myrtle Beach | South Carolina | 29572 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Dallas | Texas | 75235 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Falls Church | Virginia | 22042 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Seattle | Washington | 98109 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Tacoma | Washington | 98405 | United States | Details |
| Research Site | NOT_YET_RECRUITING | Milwaukee | Wisconsin | 53226 | United States | Details |
| Research Site | WITHDRAWN | Auchenflower | 4066 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Ballarat | 3350 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Clayton | 3168 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Darlinghurst | 2010 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Elizabeth Vale | 5112 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | South Brisbane | 4101 | Australia | Details | |
| Research Site | WITHDRAWN | St Albans | 3021 | Australia | Details | |
| Research Site | NOT_YET_RECRUITING | Barretos | 14784-400 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | Curitiba | 81520-060 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | Salvador | 41950-640 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | São Paulo | 01323-903 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | São Paulo | 05652-900 | Brazil | Details | |
| Research Site | NOT_YET_RECRUITING | Calgary | Alberta | T2N 5G2 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Abbotsford British Columbia | British Columbia | V2S0C2 | Canada | Details |
| Research Site | RECRUITING | Barrie | Ontario | L4M 6M2 | Canada | Details |
| Research Site | RECRUITING | Hamilton | Ontario | L8V 5C2 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Kingston | Ontario | K7L 2V7 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | London | Ontario | N6C 2R5 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Mississauga | Ontario | L5M 2N1 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Montreal | Quebec | H2X 0A9 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Montreal | Quebec | H3A 1A1 | Canada | Details |
| Research Site | NOT_YET_RECRUITING | Beijing | 100034 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Beijing | 100050 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Beijing | 100191 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Changsha | 410013 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chengdu | 610000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chengdu | 610072 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chongqing | 400016 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Chongqing | 400030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Fuzhou | 350005 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Guangzhou | 510220 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Guangzhou | 510288 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Guiyang | 550044 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Hangzhou | 310003 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Hangzhou | 310009 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Harbin | 150049 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Jinan | 250012 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Jinan | 250021 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Kunming | 650101 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Kunming | 650118 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Lanzhou | 730030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Nanchang | 330006 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Nanjing | 210008 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Nanning | 530021 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Ningbo | 315010 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Qingdao | 266003 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Shanghai | 200040 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Shenyang | 110004 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Shenyang | 110042 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Suining Shi | 629000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Tianjin | 300211 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Wenzhou | 325000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Wuhan | 430022 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Wuhan | 430030 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Xuzhou | 221000 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Zhengzhou | 450008 | China | Details | |
| Research Site | NOT_YET_RECRUITING | Bordeaux | 33000 | France | Details | |
| Research Site | NOT_YET_RECRUITING | Montpellier | 34298 | France | Details | |
| Research Site | NOT_YET_RECRUITING | Paris | 75014 | France | Details | |
| Research Site | NOT_YET_RECRUITING | Pierre-Bénite | 69310 | France | Details | |
| Research Site | NOT_YET_RECRUITING | Poitiers | 86000 | France | Details | |
| Research Site | NOT_YET_RECRUITING | Strasbourg | 67098 | France | Details | |
| Research Site | NOT_YET_RECRUITING | Bochum | 44791 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Bonn | 53127 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Dresden | 01307 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Duisburg | 47169 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Frankfurt am Main | 60431 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Hamburg | 20246 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Hanover | 30625 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Herne | 44625 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Magdeburg | 39120 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Mannheim | 68167 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Marburg | 35043 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Mettmann | 40822 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Münster | 48149 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Nuremberg | 90419 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Nürtingen | 72622 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Regensburg | 93053 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Rostock | 18057 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Stuttgart | 70174 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Tübingen | 72076 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Ulm | 89081 | Germany | Details | |
| Research Site | NOT_YET_RECRUITING | Kolkata | 700160 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Kottayam | 686008 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Nashik | 422011 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Navi Mumbai | 410210 | India | Details | |
| Research Site | NOT_YET_RECRUITING | New Delhi | 110076 | India | Details | |
| Research Site | NOT_YET_RECRUITING | New Delhi | 110085 | India | Details | |
| Research Site | NOT_YET_RECRUITING | New Delhi | 11029 | India | Details | |
| Research Site | NOT_YET_RECRUITING | Bari | 70120 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Florence | 50134 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Padova | 35128 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Roma | 00168 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Rozzano | 20089 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Tricase | 73039 | Italy | Details | |
| Research Site | NOT_YET_RECRUITING | Fukuoka | 811-1347 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Fukuoka | 812-8582 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Hamamatsu | 431-3192 | Japan | Details | |
| Research Site | WITHDRAWN | Hirosaki-shi | 036-8563 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kanazawa | 920-8641 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kashihara-shi | 634-8522 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kawasaki-shi | 216-8511 | Japan | Details | |
| Research Site | WITHDRAWN | Kita-gun | 761-0793 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kobe | 650-0017 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kōtoku | 135-8550 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Kumamoto | 860-0008 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Nagasaki | 852-8501 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Nagoya | 466-8560 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Osaka | 541-8567 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Osaka | 545-8586 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Toyama | 930-0194 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Tsukuba | 305-8576 | Japan | Details | |
| Research Site | NOT_YET_RECRUITING | Gdansk | 80-952 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Koszalin | 75-581 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Poznan | 61-731 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Siedlce | 08-110 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Skórzewo | 60-185 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Wroclaw | 50-556 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Wroclaw | 53-413 | Poland | Details | |
| Research Site | NOT_YET_RECRUITING | Seoul | 03080 | South Korea | Details | |
| Research Site | NOT_YET_RECRUITING | Seoul | 06591 | South Korea | Details | |
| Research Site | NOT_YET_RECRUITING | Seoul | 3722 | South Korea | Details | |
| Research Site | NOT_YET_RECRUITING | Seoul | 5505 | South Korea | Details | |
| Research Site | NOT_YET_RECRUITING | Seoul | 6351 | South Korea | Details | |
| Research Site | NOT_YET_RECRUITING | L'Hospitalet de Llobregat | 08908 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Las Palmas de Gran Canaria | 35016 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Madrid | 28040 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Santander | 39008 | Spain | Details | |
| Research Site | NOT_YET_RECRUITING | Seville | 41013 | Spain | Details | |
| Research Site | RECRUITING | Kaohsiung City | 80756 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Kaohsiung City | 813 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Kaohsiung City | 83301 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Tainan | 704 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Taipei | 11217 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Taoyuan | 333 | Taiwan | Details | |
| Research Site | NOT_YET_RECRUITING | Bangkok | 10700 | Thailand | Details | |
| Research Site | NOT_YET_RECRUITING | Hat Yai | 90110 | Thailand | Details | |
| Research Site | NOT_YET_RECRUITING | Bristol | BS2 8ED | United Kingdom | Details | |
| Research Site | NOT_YET_RECRUITING | Cambridge | CB2 0QQ | United Kingdom | Details | |
| Research Site | NOT_YET_RECRUITING | Preston | PR2 9HT | United Kingdom | Details | |
| Research Site | NOT_YET_RECRUITING | Sheffield | S10 2SJ | United Kingdom | Details |