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| ID | DOID:2156 |
| Name | ovarian germ cell cancer |
| Definition | An ovarian cancer that originates in the germ (egg) cells of the ovary. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Path | disease disease of cellular proliferation cancer organ system cancer reproductive organ cancer female reproductive organ cancer ovarian cancer ovarian germ cell cancer |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|---|---|---|---|
| MLH1 negative | Pembrolizumab | ovarian germ cell cancer | sensitive | detail... |
| MSH6 negative | Pembrolizumab | ovarian germ cell cancer | sensitive | detail... |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02834013 | Phase II | Ipilimumab + Nivolumab | Nivolumab and Ipilimumab in Treating Patients With Rare Tumors | Active, not recruiting | USA | 1 |
| NCT04876456 | Phase II | Cabozantinib | A Phase II Trial Evaluating the Efficacy of Cabozantinib With Patients With Refractory GCTs | Active, not recruiting | USA | 0 |
| NCT06937866 | Phase Ib/II | Etoposide + XL092 | Maintenance Zanzalintinib With Etoposide After HDCT in GCT | Recruiting | USA | 0 |