thymoma
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ID DOID:3275
Name thymoma
Definition A thymus cancer that derives_from epithelial cells located_in the thymus. The tumor cells in a thymoma look similar to the normal cells of the thymus, grow slowly, and rarely spread beyond the thymus.
Source DiseaseOntology.org
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Path disease disease of cellular proliferation cancer organ system cancer immune system cancer thymus cancer thymoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
TP53 loss Selinexor thymoma predicted - resistant detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01011439 Phase II Milciclib Phase II Study Of Oral PHA-848125AC In Patients With Thymic Carcinoma Terminated USA | ITA | FRA 0
NCT01025089 Phase II Cetuximab Cisplatin + Cyclophosphamide + Doxorubicin Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma Active, not recruiting USA 0
NCT01301391 Phase II Milciclib Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of Chemotherapy Terminated USA | ITA 0
NCT01621568 Phase II Sunitinib Sunitinib for Advanced Thymus Cancer Following Earlier Treatment Completed USA 0
NCT02220855 Phase II Buparlisib A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas Completed USA 0
NCT02721732 Phase II Pembrolizumab Study for the Evaluation of Efficacy of Pembrolizumab (MK-3475) in Patients With Rare Tumors Active, not recruiting USA 0
NCT03023319 Phase I Bosutinib + Pemetrexed Disodium Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors Completed USA 0
NCT03076554 Phase II Avelumab A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy Recruiting USA 0
NCT03134118 Phase II Nivolumab Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM) (NIVOTHYM) Unknown status NLD | GBR | FRA | ESP | CHE | BEL 0
NCT03193437 Phase II Selinexor Selinexor in Patients With Advanced Thymic Epithelial Tumor Progressing After Primary Chemotherapy Terminated USA 0
NCT03295227 Phase I Pembrolizumab Feasibility Trial of Pembrolizumab in Unresectable Thymoma and Thymic Carcinoma Recruiting USA 0
NCT03449173 Phase II Sunitinib Trial of Sunitinib in Patients With Type B3 Thymoma or Thymic Carcinoma in Second and Further Lines (Style Trial) (Style) Unknown status ITA 0
NCT03517488 Phase I XmAb20717 A Study of XmAb20717 in Subjects With Selected Advanced Solid Tumors (DUET-2) Completed USA 0
NCT03556228 Phase I VMD-928 Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma Recruiting USA 1
NCT04417660 Phase II Bintrafusp alfa Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma Recruiting USA 0
NCT04710628 Phase II Lenvatinib + Pembrolizumab Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIents (PECATI) Active, not recruiting ITA | FRA | ESP 0
NCT05228015 Phase I IK-930 Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors Terminated USA | GBR | AUS 0
NCT06248515 Phase II Sacituzumab govitecan-hziy A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors Recruiting USA 0
NCT06444815 Phase I VET3-TGI Pembrolizumab + VET3-TGI A Study of VET3-TGI in Patients With Solid Tumors (STEALTH-001) Recruiting USA 0
NCT06790706 Phase II AB154 + Zimberelimab AB154 + Fluorouracil + Leucovorin + Oxaliplatin + Zimberelimab IMMUNORARE5: A National Platform of 5 Academic Phase II Trials Coordinated by Lyon University Hospital to Assess the Safety and the Efficacy of the IMMUNOtherapy With Domvanalimab + Zimberelimab Combination in Patients With Advanced RARE Cancers (IMMUNORARE5) Not yet recruiting FRA 0