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ID | DOID:350 |
Name | mastocytosis |
Definition | |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of anatomical entity hematopoietic system disease leukocyte disease mastocytosis |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
KIT D419del | Imatinib | mastocytosis | predicted - sensitive | detail... |
KIT K509I | Imatinib | mastocytosis | sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT00814073 | Phase III | Masitinib | A Phase 3 Study to Compare Efficacy and Safety of Masitinib to Placebo in the Treatment of Patients With Smouldering Systemic, Indolent Systemic or Cutaneous Mastocytosis With Handicap | Completed | USA | FRA | 0 |
NCT04333108 | Phase III | Masitinib | Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis Unresponsive to Optimal Symptomatic Treatment | Recruiting | ROU | POL | NLD | GBR | FRA | DEU | 2 |
NCT06327685 | Phase I | Avapritinib + Decitabine Avapritinib + Decitabine and Cedazuridine | Avapritinib With Decitabine in Patients With SM-AHN | Recruiting | USA | 0 |