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ID | DOID:4451 |
Name | renal carcinoma |
Definition | A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products). |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation cancer organ system cancer urinary system cancer kidney cancer renal carcinoma |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
PTEN loss | Gedatolisib | renal carcinoma | decreased response | detail... |
PTEN loss VHL loss | Gedatolisib | renal carcinoma | decreased response | detail... |
PTEN loss | Capivasertib | renal carcinoma | sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT03050060 | Phase II | Nelfinavir + Nivolumab | Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, and Nivolumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer | Terminated | USA | 0 |
NCT03685448 | Phase II | Cabozantinib | ANZUP - Non-clear Cell Post Immunotherapy CABozantinib (UNICAB) (UNICAB) | Unknown status | AUS | 0 |
NCT04095273 | Phase I | Elimusertib + Pembrolizumab | Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the ATR Inhibitor BAY1895344 in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug | Completed | USA | GBR | ESP | DEU | CHE | 0 |