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ID | DOID:4866 |
Name | salivary gland adenoid cystic carcinoma |
Definition | A salivary gland carcinoma that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures within the affected organ. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes. |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer oral cavity cancer salivary gland cancer salivary gland carcinoma salivary gland adenoid cystic carcinoma |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
TP53 wild-type | SAR405838 | salivary gland adenoid cystic carcinoma | predicted - sensitive | detail... |
FGFR1 positive | Rogaratinib | salivary gland adenoid cystic carcinoma | predicted - sensitive | detail... |
TP53 wild-type | Cisplatin + SAR405838 | salivary gland adenoid cystic carcinoma | predicted - sensitive | detail... |
ATM P1069fs ATM LOH | Ceralasertib + Olaparib | salivary gland adenoid cystic carcinoma | predicted - sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT01678105 | Phase II | Dovitinib | A Phase II Study of Dovitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands (DOVE) | Completed | CAN | 0 |
NCT03146650 | Phase II | Ipilimumab + Nivolumab | Nivolumab and Ipilimumab in Treating Patients With Metastatic Recurrent Major or Minor Salivary Gland Cancer | Active, not recruiting | USA | 0 |
NCT05010629 | Phase II | Carboplatin + Elraglusib | 9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma | Active, not recruiting | USA | 0 |