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ID DOID:4992
Name optic nerve glioma
Definition
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer nervous system cancer central nervous system cancer cranial nerve malignant neoplasm optic nerve neoplasm optic nerve glioma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01089101 Phase Ib/II Selumetinib Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma Active, not recruiting USA 0
NCT02095132 Phase Ib/II Adavosertib + Irinotecan Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors Completed USA | CAN 0
NCT02390843 Phase I Cyclophosphamide + Filgrastim + Simvastatin + Topotecan Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors (AflacST1402) Completed USA 0
NCT02698254 Phase 0 Bevacizumab Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy Active, not recruiting USA 0
NCT03326388 Phase Ib/II Selumetinib Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (INSPECT) Completed GBR 0
NCT03871257 Phase III Carboplatin + Vincristine Sulfate Selumetinib A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma Recruiting USA | CAN 1
NCT04465643 Phase I Ipilimumab + Nivolumab Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor Recruiting USA 0
NCT06104488 Phase I RO5126766 A Study of Avutometinib for People With Solid Tumor Cancers Recruiting USA 0