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| ID | DOID:4992 |
| Name | optic nerve glioma |
| Definition | |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Path | disease disease of cellular proliferation cancer organ system cancer nervous system cancer central nervous system cancer cranial nerve malignant neoplasm optic nerve neoplasm optic nerve glioma |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT01089101 | Phase Ib/II | Selumetinib | Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma | Active, not recruiting | USA | 0 |
| NCT02095132 | Phase Ib/II | Adavosertib + Irinotecan | Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors | Completed | USA | CAN | 0 |
| NCT02390843 | Phase I | Cyclophosphamide + Filgrastim + Simvastatin + Topotecan | Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors (AflacST1402) | Completed | USA | 0 |
| NCT02698254 | Phase 0 | Bevacizumab | Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy | Active, not recruiting | USA | 0 |
| NCT03326388 | Phase Ib/II | Selumetinib | Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (INSPECT) | Completed | GBR | 0 |
| NCT03871257 | Phase III | Carboplatin + Vincristine Sulfate Selumetinib | A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma | Active, not recruiting | USA | CAN | 1 |
| NCT04465643 | Phase I | Ipilimumab + Nivolumab | Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor | Completed | USA | 0 |
| NCT06104488 | Phase I | RO5126766 | A Study of Avutometinib for People With Solid Tumor Cancers | Recruiting | USA | 0 |