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ID DOID:50922
Name gastrointestinal carcinoma
Definition A gastrointestinal system cancer that has_material_basis_in epithelial cells.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer gastrointestinal carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03724071 Phase Ib/II Flucytosine + TG6002 Study of TG6002 (VV TK-RR-FCU1) in Combination With 5-FC in Patients With Advanced Gastro-intestinal Tumors. Terminated FRA | ESP | BEL 0
NCT04426669 Phase Ib/II Aldesleukin + CISH-inactivated autologous TILs + Cyclophosphamide + Fludarabine A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering Active, not recruiting USA 0
NCT05848843 Phase I Adagrasib + Durvalumab A Phase I Study of Adagrasib and Durvalumab for Treatment of Advanced Non-small Cell Lung Cancers and Gastro-intestinal Cancers Harboring KRAS G12C Mutations Withdrawn USA 0
NCT06690281 Phase II Cyclophosphamide + Fludarabine Aldesleukin + Autologous KRAS mutant TCR-transduced PBLs A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies Not yet recruiting USA 0
NCT06859762 Phase I YL217 A First-in-Human Study of YL217 in Patients with Advanced Solid Tumors Not yet recruiting USA 0