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ID | DOID:5690 |
Name | well-differentiated liposarcoma |
Definition | A liposarcoma that is characterized as a slow growing, painless tumor usually located in the retroperitoneum or the limbs and derives_from proliferating mature adipocytes. |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation cancer organ system cancer musculoskeletal system cancer connective tissue cancer liposarcoma well-differentiated liposarcoma |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
MDM2 amp TP53 wild-type | BI 907828 | well-differentiated liposarcoma | predicted - sensitive | detail... |
MDM2 amp | N/A | well-differentiated liposarcoma | not applicable | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT04438824 | Phase II | Palbociclib + Retifanlimab | Palbociclib and INCMGA00012 in People With Advanced Liposarcoma | Active, not recruiting | USA | 0 |
NCT04979442 | Phase III | Trabectedin Milademetan | Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma (MANTRA) (MANTRA) | Terminated | USA | POL | ITA | IRL | GBR | FRA | ESP | DEU | CAN | BEL | AUT | 4 |
NCT05580588 | Phase II | SPH4336 | Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas | Terminated | USA | 0 |
NCT06414434 | Phase I | BTX-A51 | BTX-A51 in Patients With Liposarcoma | Recruiting | USA | 0 |