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ID | DOID:80167 |
Name | myeloid and lymphoid neoplasms associated with FGFR1 abnormalities |
Definition | A myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 that is characterized by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation cancer organ system cancer hematologic cancer bone marrow cancer myeloid neoplasm myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 myeloid and lymphoid neoplasms associated with FGFR1 abnormalities |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
---|---|---|---|---|
FGFR1 rearrange | Pemigatinib | myeloid and lymphoid neoplasms associated with FGFR1 abnormalities | sensitive | detail... |
FGFR1 rearrange | Midostaurin | myeloid and lymphoid neoplasms associated with FGFR1 abnormalities | sensitive | detail... |
FGFR1 rearrange | Ponatinib | myeloid and lymphoid neoplasms associated with FGFR1 abnormalities | sensitive | detail... |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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