Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| ID | DOID:0080643 |
| Name | B-lymphoblastic leukemia/lymphoma with BCR-ABL1 |
| Definition | A B-lymphoblastic leukemia/lymphoma that derives_from B-lymphoblasts and carries a translocation between the BCR gene on chromosome 22 and the ABL1 gene on chromosome 9. It results in the production of the p190 kd or p210 kd fusion protein. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Xrefs |
ICDO:9812/3
|
| Path | disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia lymphoid leukemia acute leukemia acute lymphoblastic leukemia B-cell acute lymphoblastic leukemia B-lymphoblastic leukemia/lymphoma B-lymphoblastic leukemia/lymphoma with BCR-ABL1 |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07614022 | Phase I | Blinatumomab + Dexamethasone + LP-118 + Methotrexate + Ponatinib | A Phase I Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive ALL | Not yet recruiting | USA | 0 |