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| ID | DOID:0080830 |
| Name | childhood low-grade glioma |
| Definition | A low-grade glioma that occurs in children and encompasses tumors of astrocytic, oligodendroglial, and mixed glial-neuronal histology. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Path | disease disease of cellular proliferation benign neoplasm cell type benign neoplasm low grade glioma childhood low-grade glioma |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|---|---|---|---|
| BRAF fusion | Tovorafenib | childhood low-grade glioma | sensitive | detail... |
| BRAF V600X | Tovorafenib | childhood low-grade glioma | sensitive | detail... |
| BRAF rearrange | Tovorafenib | childhood low-grade glioma | sensitive | detail... |
| BRAF V600E | Vemurafenib | childhood low-grade glioma | sensitive | detail... |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06712875 | Phase Ib/II | Dabrafenib + Nivolumab + Trametinib Nivolumab + Trametinib | MAPK Inhibition Combined with Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas | Recruiting | USA | 0 |