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ID | DOID:81277 |
Name | diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype |
Definition | A high grade glioma that is characterized by the absence of histone H3, IDH1, and IDH2 mutations. |
Source | DiseaseOntology.org |
Alt Ids | |
Path | disease disease of cellular proliferation cancer cell type cancer high grade glioma diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype |
Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT06413706 | Phase II | Abemaciclib + Temozolomide Temozolomide | A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy | Not yet recruiting | USA | ROU | ITA | FRA | ESP | DNK | BEL | 1 |