hypereosinophilic syndrome
Disease Detail

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ID DOID:999
Name hypereosinophilic syndrome
Definition A leukocyte disease that is characterized by high numbers of eosinophils which over time enter various tissues, eventually damaging organs.
Source DiseaseOntology.org
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SNOMEDCT_US_2023_03_01:418928000
Path disease disease of anatomical entity hematopoietic system disease leukocyte disease hypereosinophilic syndrome

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
JAK1 R629_S632delinsSA Ruxolitinib hypereosinophilic syndrome predicted - resistant detail...
JAK1 R629_S632delinsSA Tofacitinib hypereosinophilic syndrome predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03801434 Phase II Ruxolitinib Ruxolitinib in Treating Patients with Hypereosinophilic Syndrome or Primary Eosinophilic Disorders Recruiting USA 0